CAS 62780-89-6

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Description:

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one is a chemical compound characterized by its unique structure, which includes a benzimidazole core substituted with a 3-chloropropyl group. This compound typically exhibits properties associated with both the benzimidazole and alkyl halide functional groups. Benzimidazoles are known for their diverse biological activities, including antimicrobial and anti-inflammatory properties, while the presence of the chloropropyl group may enhance lipophilicity and influence the compound's reactivity. The molecular structure suggests potential applications in pharmaceuticals or agrochemicals, as compounds with similar frameworks often serve as intermediates or active ingredients in various therapeutic agents. Additionally, the compound's stability, solubility, and reactivity can be influenced by the presence of the chlorine atom, which may participate in nucleophilic substitution reactions. Overall, this compound represents a class of substances that could be of interest in medicinal chemistry and material science due to its structural features and potential biological activities.

Formula: C₁₀H₁₁ClN₂O

InChI: InChI=1S/C10H11ClN2O/c11-6-3-7-13-9-5-2-1-4-8(9)12-10(13)14/h1-2,4-5H,3,6-7H2,(H,12,14)

InChI key: InChIKey=GUMPYDGUYXOYML-UHFFFAOYSA-N

SMILES: C(CCCl)N1C=2C(NC1=O)=CC=CC2

Synonyms:

• 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
• 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one
• 1-(3-Chloropropyl)-2,3-dihydro-1H-1,3-benzodiazol-2-one
• 2H-Benzimidazol-2-one, 1-(3-chloropropyl)-1,3-dihydro-

1-(3-Chloropropyl)-1,3-Dihydro-2H-Benzimidazol-2-One

CAS: 62780-89-6

Formula: C₁₀H₁₁ClN₂O

Purity: 90%

Color and Shape: Solid

Molecular weight: 210.6601

Ref: IN-DA00374Y

Domperidone Impurity 1

CAS: 62780-89-6

Formula: C₁₀H₁₁ClN₂O

Color and Shape: Off-White Solid

Molecular weight: 210.66

Ref: 4Z-D-499

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

CAS: 62780-89-6

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Purity: 90%

Molecular weight: 210.66014g/mol

Ref: 54-OR5507

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

CAS: 62780-89-6

Color and Shape: Neat

Ref: 86-MM0107.10

1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one (>85%)

Controlled Product

CAS: 62780-89-6

Applications 1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one is a benzimidazole derivative used in the preparation of neuroleptic and antiallergic agents.
References Strupczewski, J. et al.: J. Med. Chem., 28, 761 (1985); Freter, K. et al.: Arzneim.-Forsch., 35, 272 (1985);

Formula: C₁₀H₁₁ClN₂O

Purity: ~90%

Color and Shape: White To Beige

Molecular weight: 210.66

Ref: TR-C379825

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one

CAS: 62780-89-6

Phenylmethyl (PM) is a drug that belongs to the class of phenylmethanesulfonamides. It is used in the treatment of diarrhea, specifically in cases where there are no other suitable anti-diarrheal drugs available. The active form of PM is 1-(3-chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one (PCP). This drug inhibits bacterial growth by binding to the 50S ribosomal subunit and inhibiting protein synthesis. PCP has been shown to have a narrow spectrum of activity against most enteric bacteria and some protozoa. The drug is poorly absorbed from the gastrointestinal tract and does not cross the blood–brain barrier, which limits its use for systemic infections.

Formula: C₁₀H₁₁ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 210.66 g/mol

Ref: 3D-FC36775

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

CAS: 62780-89-6

Formula: C₁₀H₁₁ClN₂O

Purity: 90%

Color and Shape: Solid

Molecular weight: 210.66

Ref: 10-F068821

Domperidone Impurity 1

CAS: 62780-89-6

Formula: C₁₀H₁₁ClN₂O

Molecular weight: 210.66

Ref: ST-EA-CP-D4008