CAS 634-03-7

Phendimetrazine

Description:

Phendimetrazine is a sympathomimetic amine that is primarily used as an appetite suppressant in the treatment of obesity. It acts as a central nervous system stimulant, similar to amphetamines, and works by increasing the release of norepinephrine in the brain, which helps to reduce hunger. The chemical formula for phendimetrazine is C12H17N, and it features a phenyl group attached to a dimethylated piperidine structure. This compound is typically administered in its salt form, often as phendimetrazine tartrate. It is classified as a controlled substance in many jurisdictions due to its potential for abuse and dependence. Common side effects may include increased heart rate, elevated blood pressure, insomnia, and anxiety. Phendimetrazine is usually prescribed as part of a comprehensive weight management program that includes dietary changes and physical activity. Due to its stimulant properties, caution is advised in patients with a history of cardiovascular issues or substance use disorders.

Formula: C₁₂H₁₇NO

InChI: InChI=1/C12H17NO/c1-10-12(14-9-8-13(10)2)11-6-4-3-5-7-11/h3-7,10,12H,8-9H2,1-2H3/t10-,12+/m0/s1

InChI key: InChIKey=MFOCDFTXLCYLKU-CMPLNLGQSA-N

SMILES: C[C@H]1[C@@H](OCCN1C)C2=CC=CC=C2

Synonyms:

• (+)-3,4-Dimethyl-2-phenylmorpholine
• (+)-Phendimetrazine
• (2S,3S)-3,4-Dimethyl-2-phenylmorpholine
• Antapentan
• Bontril
• Fendimetrazina
• Mephenmetrazine
• Morpholine, 3,4-dimethyl-2-phenyl-, (+)-
• Morpholine, 3,4-dimethyl-2-phenyl-, (2S-trans)-
• Nsc 169187
• Phendimetrazin
• Sedafamen
• d-2-Phenyl-3,4-dimethylmorpholine
• Morpholine, 3,4-dimethyl-2-phenyl-, (2S,3S)-
• PHENDIMETRAZINE USP/EP/BP
• Adphen (base)

Phendimetrazine

Controlled Product

CAS: 634-03-7

Applications An Amphetamine derivative. Anorexic.Controlled substance (stimulant).
References Fernandez-Lopez, J., et al.: Drugs, 62, 915 (2002); Padwal, R., et al.: Lancet, 369, 71 (2007); Fernstrom, J., et al.: Pharmacol. Therap., 117, 105 (2008)

Formula: C₁₂H₁₇NO

Color and Shape: Neat

Molecular weight: 191.27

Ref: TR-P295800

Phendimetrazine-13C-D3 hydrochloride

Controlled Product

CAS: 634-03-7

Applications Phendimetrazine-13C-D3 hydrochloride is a labelled analogue of Phendimetrazine, an Amphetamine derivative that is a stimulant drug and used as a appetite suppressant.
References Fernandez-Lopez, J., et al.: Drugs, 62, 915 (2002), Padwal, R., et al.: Lancet, 369, 71 (2007), Fernstrom, J., et al.: Pharmacol. Therap., 117, 105 (2008),

Formula: C₁₁CH₁₄D₃NO·(HCl)

Color and Shape: Neat

Molecular weight: 231.74

Ref: TR-P295804

Phendimetrazine (1.0mg/ml in Methanol)

Controlled Product

CAS: 634-03-7

Formula: C₁₂H₁₇NO

Color and Shape: Single Solution

Molecular weight: 191.27

Ref: TR-KIT2320