CAS 6341-92-0

6-Chloroisatin

Description:

6-Chloroisatin is an organic compound characterized by its structure, which includes a chloro substituent at the 6-position of the isatin framework. Isatin itself is a bicyclic compound derived from indole, featuring a carbonyl group and an amine group, making it a versatile building block in organic synthesis. The presence of the chlorine atom enhances its reactivity and can influence its biological activity, making it of interest in medicinal chemistry. 6-Chloroisatin typically appears as a solid at room temperature and is soluble in various organic solvents. Its chemical properties include the ability to undergo various reactions such as nucleophilic substitutions and cycloadditions, which are valuable in the synthesis of more complex molecules. Additionally, compounds like 6-Chloroisatin have been studied for their potential pharmacological properties, including antimicrobial and anticancer activities. As with many halogenated compounds, safety precautions should be taken when handling 6-Chloroisatin due to its potential toxicity and environmental impact.

Formula: C₈H₄ClNO₂

InChI: InChI=1S/C8H4ClNO2/c9-4-1-2-5-6(3-4)10-8(12)7(5)11/h1-3H,(H,10,11,12)

SMILES: c1cc2c(cc1Cl)NC(=O)C2=O

Synonyms:

• Buttpark 50\07-92
• 6-Chloro-1H-Indole-2,3-Dione
• 3-(5-{(E)-[1-(3-bromophenyl)-2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene]methyl}furan-2-yl)-4-methylbenzoic acid

6-Chloroisatin

CAS: 6341-92-0

Formula: C₈H₄ClNO₂

Purity: >98.0%(GC)(T)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 181.58

Ref: 3B-C1871

6-Chloroisatin

CAS: 6341-92-0

Formula: C₈H₄ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 181.5759

Ref: IN-DA003N6J

6-Chloroisatin

CAS: 6341-92-0

6-Chloroisatin

Formula: C₈H₄ClNO₂

Purity: 98%

Color and Shape: orange solid

Molecular weight: 181.58g/mol

Ref: 54-OR40689

6-Chloroisatin

CAS: 6341-92-0

Formula: C₈H₄ClNO₂

Molecular weight: 181.58

Ref: 4Z-I-128003

6-Chloroisatin

Controlled Product

CAS: 6341-92-0

Applications 6-Chloroisatin (cas# 6341-92-0) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₈H₄NO₂Cl

Color and Shape: Neat

Molecular weight: 181.58

Ref: TR-C428808

6-Chloroisatin

CAS: 6341-92-0

6-Chloroisatin is a potent inhibitor of bacterial growth that binds to the 50S ribosomal subunit. It has been shown to have strong inhibitory activity against tuberculosis and sulphamethoxazole-resistant strains of Mycobacterium tuberculosis. 6-Chloroisatin inhibits bacterial growth by binding to the 50S ribosomal subunit, thereby preventing protein synthesis and cell division. The electron deficient form of 6-chloroisatin reacts with the electron rich sulphamethoxazole by displacement of chloride ion from the sulphonamide ring, forming a regiospecific product that inhibits bacterial respiration. This reaction system is inhibited by activated carbon, which may be a potential therapeutic strategy for patients with drug resistant tuberculosis.

Formula: C₈H₄ClNO₂

Purity: Min. 95%

Molecular weight: 181.58 g/mol

Ref: 3D-FC32700

6-Chloroisatin

CAS: 6341-92-0

Formula: C₈H₄ClNO₂

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 181.58

Ref: 10-F040367