CAS 635318-11-5

(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide

Description:

(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide, with CAS number 635318-11-5, is a bicyclic compound characterized by its unique structural features, including a thiabicyclic framework and multiple functional groups. The presence of amino and carboxylic acid groups suggests that it may exhibit both basic and acidic properties, making it potentially useful in various biochemical applications. The stereochemistry indicated by the (1R,4S,5S,6S) configuration implies that the compound has specific spatial arrangements that can influence its reactivity and interactions with biological systems. Additionally, the dioxo group contributes to its chemical stability and reactivity. This compound may be of interest in medicinal chemistry and drug development due to its potential biological activity, although specific biological properties and applications would require further investigation. Overall, its unique structure and functional groups suggest a versatile compound with potential utility in various chemical and pharmaceutical contexts.

Formula: C₇H₉NO₆S

InChI: InChI=1S/C7H9NO6S/c8-7(6(11)12)1-15(13,14)4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1

InChI key: InChIKey=AVDUGNCTZRCAHH-MDASVERJSA-N

SMILES: C(O)(=O)[C@@]1(N)[C@]2([C@]([C@@H]2C(O)=O)(S(=O)(=O)C1)[H])[H]

Synonyms:

• (1R,4S,5S,6S)-4-Amino-2-Thiabicyclo[3.1.0]Hexane-4,6-Dicarboxylic Acid 2,2-Dioxide (Ly 404039)
• (1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide
• 2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, 4-amino-, 2,2-dioxide, (1R,4S,5S,6S)-
• Ly 404039
• Ly 404040
• Pomaglumetad

LY-404039

CAS: 635318-11-5

Formula: C₇H₉NO₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.2145

Ref: IN-DA00ECE0

LY404039

CAS: 635318-11-5

LY404039

Purity: ≥98%

Molecular weight: 235.22g/mol

Ref: 54-BUP11251

LY404039

CAS: 635318-11-5

LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).

Formula: C₇H₉NO₆S

Purity: 99% - 99.92%

Color and Shape: Solid

Molecular weight: 235.22

Ref: TM-T6022

LY 404039

CAS: 635318-11-5

LY-404039 is a potent metabotropic glutamate receptor agonist with nanomolar affinity for group II receptors mGluR2 (Ki = 149 nM) and mGluR3 (Ki = 92 nM). It modulates glutamatergic activity in limbic and forebrain areas and has antipsychotic properties in animal studies. LY-404039 represents a potential new therapy for neurophysiatric disorders including schizophrenia, psychosis and anxiety.

Formula: C₇H₉NO₆S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 235.01506

Ref: 3D-FL65070