CAS 635318-11-5

(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide

Formula: C₇H₉NO₆S

InChI: InChI=1S/C7H9NO6S/c8-7(6(11)12)1-15(13,14)4-2(3(4)7)5(9)10/h2-4H,1,8H2,(H,9,10)(H,11,12)/t2-,3-,4+,7+/m1/s1

InChI key: InChIKey=AVDUGNCTZRCAHH-MDASVERJSA-N

SMILES: C(O)(=O)[C@@]1(N)[C@]2([C@]([C@@H]2C(O)=O)(S(=O)(=O)C1)[H])[H]

Synonyms:

• (1R,4S,5S,6S)-4-Amino-2-Thiabicyclo[3.1.0]Hexane-4,6-Dicarboxylic Acid 2,2-Dioxide (Ly 404039)
• (1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide
• 2-Thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid, 4-amino-, 2,2-dioxide, (1R,4S,5S,6S)-
• Ly 404039
• Ly 404040
• Pomaglumetad

LY404039

CAS: 635318-11-5

LY404039

Formula: C₇H₉NO₆S

Purity: 99.5%

Molecular weight: 235.22

Ref: 54-BUP11251

LY404039

CAS: 635318-11-5

LY404039 (pomaglumetad) is an effective agonist of recombinant human mGlu2(Ki =149 nM)/mGlu3(Ki =92 nM).

Formula: C₇H₉NO₆S

Purity: 99% - 99.92%

Color and Shape: Solid

Molecular weight: 235.214

Ref: TM-T6022

LY 404039

CAS: 635318-11-5

LY-404039 is a potent metabotropic glutamate receptor agonist with nanomolar affinity for group II receptors mGluR2 (Ki = 149 nM) and mGluR3 (Ki = 92 nM). It modulates glutamatergic activity in limbic and forebrain areas and has antipsychotic properties in animal studies. LY-404039 represents a potential new therapy for neurophysiatric disorders including schizophrenia, psychosis and anxiety.

Formula: C₇H₉NO₆S

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 235.01506

Ref: 3D-FL65070

LY404039

CAS: 635318-11-5

(1R,4S,5S,6S)-4-Amino-2-thiabicyclo[3.1.0]hexane-4,6-dicarboxylic acid 2,2-dioxide

Formula: C₇H₉NO₆S

Purity: 98%

Molecular weight: 235.21

Ref: IN-DG167188

LY-404039

CAS: 635318-11-5

Formula: C₇H₉NO₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.2145

Ref: IN-DA00ECE0