CAS 63610-08-2

Indobufen

Description:

Indobufen is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, thereby reducing pain and inflammation. Indobufen is often utilized in the treatment of various conditions, including arthritis and other inflammatory disorders. The compound is typically administered orally and is known for its relatively rapid onset of action. Its chemical structure includes a phenyl group and a butyric acid moiety, contributing to its pharmacological effects. Indobufen is also noted for its potential side effects, which may include gastrointestinal disturbances and cardiovascular risks, similar to other NSAIDs. As with any medication, it is essential to use Indobufen under medical supervision to manage dosage and monitor for adverse reactions. Overall, Indobufen represents a valuable option in the management of pain and inflammation, with a specific profile that distinguishes it from other NSAIDs.

Formula: C₁₈H₁₇NO₃

InChI: InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)

InChI key: InChIKey=AYDXAULLCROVIT-UHFFFAOYSA-N

SMILES: O=C1N(CC=2C1=CC=CC2)C3=CC=C(C(C(O)=O)CC)C=C3

Synonyms:

• (2R)-2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid
• 1-Oxo-2-[p-[(α-ethyl)carboxymethyl]phenyl]isoindoline
• 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid
• 2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid
• 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric acid
• 4-(1,3-Dihydro-1-oxo-(2H)-isoindol-2-yl)-alpha-ethylbenzeneacetic acid
• 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid
• Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-
• Ibustrin
• K 2930
• K 3920

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 295.34

Ref: 3B-I1178

(2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 295.3325

Ref: IN-DA01CBW2

Indobufen

CAS: 63610-08-2

Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor.

Formula: C₁₈H₁₇NO₃

Purity: 99.27% - 99.44%

Color and Shape: White Solid

Molecular weight: 295.33

Ref: TM-T15577

Indobufen

CAS: 63610-08-2

Indobufen

Formula: C₁₈H₁₇NO₃

Purity: ≥98%

Molecular weight: 295.33

Ref: 54-BUP13709

2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid

CAS: 63610-08-2

2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid

Formula: C₁₈H₁₇NO₃

Purity: >99%

Molecular weight: 295.33

Ref: 54-OR1029819

Indobufen-d5

CAS: 63610-08-2

Formula: C₁₈H₁₂D₅NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 300.37

Ref: 4Z-I-5110

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 295.34

Ref: 4Z-I-511

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Molecular weight: 295.33

Ref: 7W-GP5189

Indobufen

CAS: 63610-08-2

Indobufen is a drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to be effective in treating infectious diseases, including malaria and bacterial infections. Indobufen has been shown to inhibit the production of prostaglandin E2 (PGE2) in an experimental model at low doses. This inhibition leads to reduced levels of PGE2 receptor activity and decreased enzyme activities such as cyclooxygenase and lipoxygenase, which are involved in inflammation. This drug also inhibits platelet aggregation and increases bleeding time. The effects of indobufen on human pharmacokinetics have been studied using human serum and platelet samples from healthy volunteers. Indobufen is rapidly absorbed, with a half-life of 1 hour, and it is metabolized by cytochrome P450 (CYP450). Indobufen has also been shown to increase cardiac contractility without affecting heart rate or blood pressure levels.

Formula: C₁₈H₁₇NO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 295.33 g/mol

Ref: 3D-FI37690

Indobufen

CAS: 63610-08-2

Ref: BE-RMCI058000

Indobufen D5

CAS: 63610-08-2

Ref: BE-RMCI52017

Indobufen

CAS: 63610-08-2

2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid

Formula: C₁₈H₁₇NO₃

Purity: 99%

Molecular weight: 295.33

Ref: IN-DG41901

Indobufen

Controlled Product

CAS: 63610-08-2

Applications Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.
References Diener, H., et al.: J. Neurol. Sci., 143, 1 (1996), Brainin, M., et al.: Eur. J. Neurol., 7, 5 (2005), Culebras, A., et al.: Neurology, 62, 1073 (2004), Lopez, A., et al.: Lancet, 367, 1747 (2006),

Formula: C₁₈H₁₇NO₃

Color and Shape: Neat

Molecular weight: 295.33

Ref: TR-I576500

Indobufen

CAS: 63610-08-2

Formula: C₁₈H₁₇NO₃

Molecular weight: 295.34

Ref: ST-EA-CP-I87000