CAS 637-07-0: Clofibrate

Description:Clofibrate is a synthetic compound classified as a fibrate, primarily used as a lipid-lowering agent in the treatment of hyperlipidemia. Its chemical formula is C12H15ClO3, and it features a chlorinated aromatic ring structure, which contributes to its pharmacological properties. Clofibrate functions by activating peroxisome proliferator-activated receptors (PPARs), leading to increased fatty acid oxidation and reduced triglyceride levels in the bloodstream. It is typically administered orally and is known for its ability to lower cholesterol levels, particularly low-density lipoprotein (LDL) and triglycerides, while potentially raising high-density lipoprotein (HDL) levels. However, its use has declined due to concerns about side effects, including gastrointestinal disturbances and potential liver toxicity. Clofibrate is also associated with an increased risk of gallstones. As a result, it is often replaced by newer agents with improved safety profiles. Despite its reduced clinical use, it remains a significant compound in the study of lipid metabolism and cardiovascular health.

Formula:C₁₂H₁₅ClO₃

InChI:InChI=1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3

InChI key:InChIKey=KNHUKKLJHYUCFP-UHFFFAOYSA-N

SMILES:O=C(OCC)C(OC1=CC=C(Cl)C=C1)(C)C

Synonyms:
2-(4-Chlorophenoxy)isobutyric acid ethyl ester
2-(p-Chlorophenoxy)-2-methylpropionic acid ethyl ester
Abitrate
Amotril
Anparton
Apolan
Arteriosan
Artevil
Ateculon
Ateriosan
See more synonyms
Atheropront
Atromid S
Atromidin
Ay 61123
Azionyl
Bioscleran
Cartagyl
Cinnarizine
Claripex
Claripex CPIB
Clobren SF
Clofibrat
Clofibrato
Clofinit
Cpib
Ecpib
Epib
Ethyl (p-chlorophenoxy) isobutyrate
Ethyl 2-(4-Chlorophenoxy)-2-Methylpropanoate
Ethyl 2-(4-Chlorophenoxy)-2-Methylpropionate
Ethyl 2-(4-chlorophenoxy)isobutyrate
Ethyl 2-(p-chlorophenoxy)-2-methylpropionate
Ethyl 2-(p-chlorophenoxy)isobutyrate
Ethyl clofibrate
Ethyl p-chlorophenoxyisobutyrate
Ethyl α-(4-chlorophenoxy)-α-methylpropionate
Ethyl α-(4-chlorophenoxy)isobutyrate
Ethyl α-(p-chlorophenoxy)-α-methylpropionate
Ethyl α-(p-chlorophenoxy)isobutyrate
Hyclorate
Ici 28257
Lipavil
Lipavlon
Lipomid
Liprinal
Miscleron
Misclerone
Neo-Atromid
Normet
Normolipol
Nsc 79389
Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, ethyl ester
Propionic acid, 2-(p-chlorophenoxy)-2-methyl-, ethyl ester
Recolip
Regelan
Serotinex
Sklerepmexe
Sklero-Tablinene
Sklerolip
Skleromexe
Ticlobran
Xyduril
p-Chlorophenoxyisobutyric acid ethyl ester

Found 15 products.

Product data	Purity	Price range	Estimated delivery
Clofibrate, 95+% REF: 02-J60342CAS: 637-07-0	95+%	To inquire	Tue 22 Apr 25
Clofibrate CRS REF: 41-C2300000CAS: 637-07-0	- - -	115.00 €	Thu 24 Apr 25
Clofibrate liquid REF: 7W-GL9707CAS: 637-07-0	- - -	To inquire	Tue 29 Apr 25
Ethyl 2-(4-chlorophenoxy)-2-methylpropanoate REF: 54-OR26850CAS: 637-07-0	98+%	177.00 €~662.00 €	Tue 29 Apr 25
Clofibrate-d4 REF: 4Z-C-242CAS: 637-07-0	- - -	To inquire	Tue 29 Apr 25
Clofibrate REF: 54-BUP17771CAS: 637-07-0	99%	52.00 €~119.00 €	Tue 29 Apr 25
Clofibrate REF: 3B-C0941CAS: 637-07-0	>98.0%(GC)	76.00 €~597.00 €	Tue 29 Apr 25
Clofibrate 100 µg/mL in Acetonitrile REF: 04-A11682000AL-100CAS: 637-07-0	- - -	To inquire	Tue 29 Apr 25
Clofibrate REF: 86-MM1934.00CAS: 637-07-0	- - -	339.00 €	Tue 29 Apr 25
Clofibrate REF: 04-C11682000CAS: 637-07-0	- - -	64.00 €	Tue 29 Apr 25
Clofibrate REF: TM-T1298CAS: 637-07-0	98.77%	35.00 €~81.00 €	Mon 05 May 25
Clofibrate RS REF: 2K-1049000021CAS: 637-07-0	- - -	To inquire	Tue 06 May 25
Clofibrate REF: TR-C586910CAS: 637-07-0	- - -	94.00 €~162.00 €	Tue 06 May 25
Clofibrate REF: 10-M01536CAS: 637-07-0	>98%	To inquire	Tue 06 May 25
Clofibrate REF: 3D-FC20499CAS: 637-07-0	Min. 95%	147.00 €~991.00 €	Wed 07 May 25