CAS 63725-49-5

1H-Pyrazolo[3,4-b]pyridin-6-aMine

Description:

1H-Pyrazolo[3,4-b]pyridin-6-amine, with the CAS number 63725-49-5, is a heterocyclic organic compound characterized by its pyrazolo and pyridine ring structures. This compound features a pyrazole ring fused to a pyridine ring, with an amino group (-NH2) located at the 6-position of the pyridine moiety. It is typically a solid at room temperature and may exhibit properties such as moderate solubility in polar solvents due to the presence of the amino group, which can engage in hydrogen bonding. The compound is of interest in medicinal chemistry and drug development, as derivatives of pyrazolo-pyridines have been studied for their potential biological activities, including anti-inflammatory and anticancer properties. Its reactivity can be influenced by the functional groups present, making it a versatile building block in organic synthesis. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper laboratory practices.

Formula: C6H6N4

InChI: InChI=1S/C6H6N4/c7-5-2-1-4-3-8-10-6(4)9-5/h1-3H,(H3,7,8,9,10)

InChI key: XOXOWZFVBMJORH-UHFFFAOYSA-N

SMILES: C1=CC(=NC2=C1C=NN2)N

1H-Pyrazolo[3,4-b]pyridin-6-amine

CAS: 63725-49-5

Formula: C₆H₆N₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 134.1386

Ref: IN-DA00EG1W

6-Amino-1H-pyrazolo[3,4-b]pyridine

CAS: 63725-49-5

6-Amino-1H-pyrazolo[3,4-b]pyridine

Color and Shape: Yellow Solid

Molecular weight: 134.14g/mol

Ref: 54-OR305401

1H-Pyrazolo[3,4-b]pyridin-6-amine

CAS: 63725-49-5

1H-Pyrazolo[3,4-b]pyridin-6-amine

Formula: C₆H₆N₄

Purity: 96%

Molecular weight: 134.14

Ref: IN-DG235515

1H-Pyrazolo[3,4-b]pyridin-6-amine

CAS: 63725-49-5

Formula: C₆H₆N₄

Purity: 97%

Molecular weight: 134.142

Ref: 10-F230264

6-Amino-1H-pyrazolo[3,4-b]pyridine

CAS: 63725-49-5

6-Amino-1H-pyrazolo[3,4-b]pyridine is a cholesterol inhibitor that belongs to the pyridine derivative class. It has been shown to decrease the level of total cholesterol and low density lipoprotein (LDL) cholesterol in rats with atherosclerosis. This drug inhibits protein synthesis by binding to the active site of HMG-CoA reductase and preventing it from forming an enzyme-substrate complex with cholesteryl ester. 6-Amino-1H-pyrazolo[3,4-b]pyridine is an enantiomeric mixture of two stereoisomers, R and S. The R isomer has been shown to be more potent than the S isomer in inhibiting HMG CoA reductase activity.

Formula: C₆H₆N₄

Purity: Min. 95%

Molecular weight: 134.14 g/mol

Ref: 3D-NCA72549