CAS 63968-64-9: Artemisinin

Description:Artemisinin is a sesquiterpene lactone with the chemical formula C15H22O5, primarily derived from the sweet wormwood plant, Artemisia annua. It is renowned for its potent antimalarial properties and is a key component in artemisinin-based combination therapies (ACTs) used to treat malaria. The compound features a unique endoperoxide bridge, which is crucial for its biological activity. Artemisinin exhibits moderate solubility in organic solvents like ethanol and chloroform but has limited solubility in water. Its mechanism of action involves the generation of reactive oxygen species upon activation by heme, leading to the destruction of malaria parasites. Artemisinin is generally well-tolerated, though it can cause side effects such as nausea and dizziness in some patients. Due to its natural origin and efficacy, research continues into optimizing its derivatives and enhancing its pharmacological properties. Additionally, ongoing studies are exploring its potential applications beyond malaria, including its effects on various cancers and other diseases.

Formula:C₁₅H₂₂O₅

InChI:InChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1

InChI key:InChIKey=BLUAFEHZUWYNDE-NNWCWBAJSA-N

SMILES:O=C1OC2OC3(OOC24C(CCC(C)C4CC3)C1C)C

Synonyms:
(+)-Arteannuin
(3R,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
(3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one
(3S,5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
(5aS,6R,8aS,9R,12S)-3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,12S,12aR)-
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one, octahydro-3,6,9-trimethyl-, [3R-(3α,5aβ,6β,8aβ,9α,12β,12aR*)]-
3,6,9-trimethyloctahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(3H)-one
ARTIVeda
Artemef
See more synonyms
Artemisine
Artemisinine
Hc 101A
Huanghuahaosu
NSC 369397
PulmoHeal
Qing Hau Sau
Qing Hau Su
Qinghaosu
Qinghosu
[3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-one
Artemisinin

Found 16 products.

Product data	Purity	Price range	Estimated delivery
Artemisinin REF: 3B-A2118CAS: 63968-64-9	>97.0%(HPLC)	46.00 €~138.00 €	Fri 25 Apr 25
Artemisinin, 98% REF: 02-J65406CAS: 63968-64-9	98%	134.00 €~381.00 €	Mon 28 Apr 25
Artemisinin RS REF: 41-ICRS43857CAS: 63968-64-9	- - -	102.00 €	Wed 30 Apr 25
Artemisinin ((3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one) REF: 45-1042747CAS: 63968-64-9	- - -	1,333.00 €	Fri 02 May 25
Artemisinin REF: IN-DA00IBB0CAS: 63968-64-9	97%	21.00 €~681.00 €	Fri 02 May 25
Artemisinin REF: TM-T0392CAS: 63968-64-9	100% - 99.87%	35.00 €~92.00 €	Fri 02 May 25
Artemisinin REF: 4Z-A-309CAS: 63968-64-9	- - -	To inquire	Mon 05 May 25
Artemisinin REF: 54-BUP16845CAS: 63968-64-9	≥98%	52.00 €~435.00 €	Mon 05 May 25
Artemisinin REF: 7W-GP0718CAS: 63968-64-9	(HPLC) ≥ 98.0%	108.00 €~309.00 €	Mon 05 May 25
Artemisinin REF: BP-BP0197CAS: 63968-64-9	95%~99%	48.00 €~88.00 €	Mon 05 May 25
Artemisinin REF: 54-BIA4320CAS: 63968-64-9	>99% (Typical Value in Batch COA)	32.00 €~862.00 €	Fri 09 May 25
Artemisinin REF: 5G-89484CAS: 63968-64-9	≥ 95.0 % (HPLC)	177.00 €~4,808.00 €	Tue 13 May 25
Artemisinin REF: 3D-FA09640CAS: 63968-64-9	Min. 95%	167.00 €~2,047.00 €	Tue 13 May 25
Artemisinin-13C-D3 REF: TR-A777504CAS: 63968-64-9	- - -	11,848.00 €	Thu 12 Jun 25
Artemisinin-d4 REF: TR-A777503CAS: 63968-64-9	- - -	5,796.00 €	Thu 12 Jun 25
Artemisinin REF: TR-A777500CAS: 63968-64-9	- - -	- - -	Discontinued product