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CAS 641-77-0

:

4-pregnene-11-B-17-A-diol-3-20-dione

Description:
4-Pregnene-11β,17α-diol-3,20-dione, commonly known as 17α-hydroxyprogesterone, is a steroid hormone that plays a crucial role in the regulation of various physiological processes. It is a derivative of progesterone and is characterized by its specific structural features, including a pregnene backbone with hydroxyl groups at the 11 and 17 positions and a ketone at the 3 and 20 positions. This compound is primarily involved in the biosynthesis of other steroid hormones and is significant in reproductive health, particularly in pregnancy. It is synthesized in the adrenal glands and gonads and is known for its role in maintaining pregnancy and regulating menstrual cycles. In clinical settings, 17α-hydroxyprogesterone is used therapeutically to prevent preterm birth in at-risk pregnancies. The substance is typically administered in various forms, including injections or oral formulations. Its pharmacological effects are mediated through interactions with specific steroid hormone receptors, influencing gene expression and cellular activity. As with many steroid hormones, its levels in the body are tightly regulated and can be affected by various physiological and pathological conditions.
Formula:C21H30O4
InChI:InChI=1/C21H30O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3
InChI key:InChIKey=LCZBQMKVFQNSJR-UJPCIWJBSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]
Synonyms:
  • (11Alpha)-11,17-Dihydroxypregn-4-Ene-3,20-Dione
  • (11Beta)-11,17-Dihydroxypregn-4-Ene-3,20-Dione
  • (11β)-11,17-Dihydroxypregn-4-ene-3,20-dione
  • 11,17-Dihydroxypregn-4-Ene-3,20-Dione
  • 11-Beta,17-Alpha-Dihydroxypregn-4-Ene-3,20-Dione
  • 11β,17α-Dihydroxypregn-4-ene-3,20-dione
  • 11β,17α-Dihydroxyprogesterone
  • 21-Dehydrohydrocortisone
  • 21-Deoxycortisol
  • 21-Deoxyhydrocortisone
  • See more synonyms
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Found 14 products.