CAS: 641571-10-0 - Nilotinib & its intermediates

Formula: C₂₈H₂₂F₃N₇O

InChI: InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)

InChI key: InChIKey=HHZIURLSWUIHRB-UHFFFAOYSA-N

SMILES: O=C(NC=1C=C(C=C(C1)C(F)(F)F)N2C=NC(=C2)C)C3=CC=C(C(=C3)NC=4N=CC=C(N4)C5=CN=CC=C5)C

Synonyms:

• 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-N-[5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl]benzamide
• 4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide
• 4-Methyl-N-[3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl]-3-[[4-(pyridin-3-yl)pyrimidin-2-yl]amino]benzamide
• 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}benzamide
• 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4 -pyridin-3-ylpyrimidin-2-yl)amino]benzamide Nilotinib(TINIBS )
• Amn 107
• Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-
• Nilotinib
• Nilotinib & its intermediates (Developing)
• Nilotinib for research
• Nilotinib, AMN107, Tasigna
• Tasigna

Nilotinib

CAS: 641571-10-0

Nilotinib (AMN107) is a second-generation Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.

• Formula: C₂₈H₂₂F₃N₇O
• Purity: 99.83%
• Color and Shape: Off-White Solid
• Molecular weight: 529.52

Nilotinib

CAS: 641571-10-0923288-90-8

• Formula: C₂₈H₃₃F₃N₇O
• Color and Shape: Pale Yellow Solid
• Molecular weight: 529.53

Nilotinib

CAS: 641571-10-0

• Formula: C₂₈H₂₂F₃N₇O
• Purity: ≥ 99.0% (dried basis)
• Color and Shape: White to off-white or pale yellow powder
• Molecular weight: 529.52

Nilotinib

CAS: 641571-10-0

• Formula: C₂₈H₂₂F₃N₇O
• Purity: >95.0%(T)(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 529.53

4-Methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamide

CAS: 641571-10-0

• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 529.5269775390625

Nilotinib

CAS: 641571-10-0

Applications Nilotinib (AMN1O7) might be useful in treatment of chronic myelogenous leukemia. It is a …

• Formula: C₂₈H₂₂F₃N₇O
• Color and Shape: Light Yellow To Beige
• Molecular weight: 529.52

Nilotinib - Bio-X â„¢

CAS: 641571-10-0

Nilotinib is tyrosine kinase inhibitor drug that is used to treat chronic myeloid leukemia (CML). …

• Formula: C₂₈H₂₂F₃N₇O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 529.52 g/mol

Nilotinib

CAS: 641571-10-0

ABL1/BCR and KIT tyrosine kinase inhibitor; PDGFRs and DDR receptor inhibitor

• Formula: C₂₈H₂₂F₃N₇O
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 529.52 g/mol