CAS 64350-24-9
:N-(2-methylpropanoyl)guanosine
Description:
N-(2-methylpropanoyl)guanosine is a modified nucleoside that features a guanosine base linked to a 2-methylpropanoyl group. This compound is characterized by its structural components, which include a purine base (guanine), a ribose sugar, and an acyl group derived from 2-methylpropanoic acid. The presence of the acyl group can influence the compound's solubility, stability, and biological activity, potentially affecting its interactions with enzymes and other biomolecules. N-(2-methylpropanoyl)guanosine may exhibit unique properties compared to unmodified guanosine, such as altered binding affinities or enhanced stability in biological systems. This modification can be of interest in biochemical research, particularly in studies involving nucleic acid interactions, signaling pathways, or drug design. As with many nucleoside derivatives, its characteristics may include specific melting points, solubility in various solvents, and reactivity under certain conditions, which are essential for understanding its potential applications in medicinal chemistry and molecular biology.
Formula:C14H19N5O6
InChI:InChI=1/C14H19N5O6/c1-5(2)11(23)17-14-16-10-7(12(24)18-14)15-4-19(10)13-9(22)8(21)6(3-20)25-13/h4-6,8-9,13,20-22H,3H2,1-2H3,(H2,16,17,18,23,24)/t6-,8-,9-,13-/m1/s1
InChI key:OXTYJSXVUGJSGM-HTVVRFAVSA-N
SMILES:CC(C)C(=Nc1nc2c(c(n1)O)ncn2[C@H]1[C@@H]([C@@H]([C@@H](CO)O1)O)O)O
Synonyms:- Guanosine, N-(2-methyl-1-oxopropyl)-
- N-(2-Methyl-1-oxopropyl)guanosine
- N2-Isobutyrylguanosine
- N-Isobutyrylguanosine
- N2-Isobutyryl-guanosine
- N2-(2-Methylpropanoyl)-Guanosine
- N2-Isobutyryl-D-guanosine
- ibu-rG
- N2-(2-METHYLPROPANOYL)-GUANOSINE USP/EP/BP
- N-{9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-6,9-dihydro-1H-purin-2-yl}-2-methylpropanamide
- N-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
- N2-ISOBUTYRYLGUANOSINE MONOHYDRATE
- N2-Isobutyrylguanosine Hydrate
- N2-iBu-Gr
- N-Isobutyryl guanosine
- N
- N2-iBu-rG
- 2
- -Isobutyrylguanosine
- See more synonyms
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
N2-Isobutyrylguanosine
CAS:Formula:C14H19N5O6Color and Shape:White to Almost white powder to crystalMolecular weight:353.34Ref: IN-DA003SNU
1g24.00€5g28.00€10g28.00€25g56.00€50g65.00€100g108.00€250g191.00€500g301.00€1kg650.00€5kg1,223.00€10kg2,306.00€N2-Iso-Butyryl Guanosine
CAS:N2-Iso-Butyryl Guanosine is a nucleoside derivative suitable for biochemical experiments and drug synthesis research.Formula:C14H19N5O6Purity:99.26%Color and Shape:White SolidMolecular weight:353.3306N2-(2-Methylpropanoyl)guanosine
CAS:N2-(2-Methylpropanoyl)guanosineFormula:C14H19N5O6Purity:97%Color and Shape:Solid-PowderMolecular weight:353.33056N2-Isobutyrylguanosine
CAS:N2-Isobutyrylguanosine is a synthetic nucleoside analog. It is activated by the enzyme thymidine kinase and inhibits the synthesis of RNA and DNA, which leads to cell death. N2-Isobutyrylguanosine has been shown to be an effective inhibitor of epidermal growth factor receptor (EGFR) in mammalian cells. This drug has also been shown to inhibit insulin-like growth factor I and phosphorothioate monomers. N2-Isobutyrylguanosine inhibits the synthesis of fatty acids, leading to a decrease in lipid content in cells.Formula:C14H19N5O6Purity:Min. 95%Color and Shape:PowderMolecular weight:353.33 g/molN-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
CAS:N-(9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramideFormula:C14H19N5O6Purity:95%Molecular weight:353.33N-Isobutyrylguanosine
CAS:Controlled ProductApplications N-Isobutyrylguanosine is used in the syntehsis of 2'-O-(o-nitrobenzyl)-3'-thioguanosine phosphoramidite which is then used to form oligonucleotides, substrates for probing the mechanism of RNA catalysis.
References Li, N., et. al.: J. Org. Chem., 79, 3647 (2014)Formula:C14H19N5O6Color and Shape:NeatMolecular weight:353.33
