CAS 64485-93-4

Cefotaxime sodium

Description:

Cefotaxime sodium is a broad-spectrum cephalosporin antibiotic used primarily for the treatment of bacterial infections. It is effective against a variety of Gram-positive and Gram-negative bacteria, making it a valuable option in clinical settings. The compound is typically administered via injection and is known for its good tissue penetration and ability to cross the blood-brain barrier, which is particularly beneficial in treating central nervous system infections. Cefotaxime sodium works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is generally well-tolerated, but potential side effects may include allergic reactions, gastrointestinal disturbances, and alterations in blood cell counts. The drug is often used in cases of pneumonia, urinary tract infections, and sepsis. Its stability in solution and compatibility with various intravenous fluids make it a practical choice for hospital use. As with all antibiotics, appropriate susceptibility testing is recommended to ensure effectiveness against specific pathogens.

Formula: C₁₆H₁₇N₅O₇S₂·Na

InChI: InChI=1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/b20-9-;/t10-,14-;/m1./s1

InChI key: InChIKey=UWNYOXHAYFLGIE-JUZDKLSSSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1COC(C)=O)[H].[Na]

Synonyms:

• (6R-(6Alpha,7Beta(Z)))-3-((Acetyloxy)Methyl)-(((2-Amine-4-Thiazolyl)(Methoxyimino)Acetyl)Amino)-8-Oxo-5-Thia-1-Azabicyclo(4,2,0)Oct-2-Ene-2-Carboxylic Acid Monosodium Salt
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, monosodium salt, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, sodium salt (1:1), (6R,7R)-
• 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-[[(2E)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-, sodium salt, (6R,7R)- (1:1)
• Baxim
• Biolog
• Biotax
• Bioxim
• Calcef
• Califrid
• CefSo
• Cefacron
• Cefantral
• Cefcan
• Cefomed
• Cefomerc
• Cefomerk
• Cefon
• Cefotam
• Cefotax
• Cefotaxim Sodium
• Cefotaxime sodium
• Cefotaxime sodium salt
• Cefoxim
• Cefronate
• Ceftim
• Ceftop
• Ceftoringe
• Chemcef
• Clafora
• Claforan
• Claftax
• Clavox
• Eaxiron
• Elkotak
• Epotazime
• Evotaxime
• Excef
• Forax
• Fortax
• Hr 756
• Novatax
• Oritaxim
• Pretor
• Ru 24756
• Sefagen
• Sodium cefotaxime
• Tolycar
• Zafixime
• sodium (6R,7R)-3-[(acetyloxy)methyl]-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cefotaxime Sodium Salt

CAS: 63527-52-6, 64485-93-4

Formula: C₁₆H₁₆N₅NaO₇S₂

Purity: >96.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 477.44

Ref: 3B-C2224

Cefotaxime sodium salt

CAS: 64485-93-4

Cefotaxime sodium salt, 64485-93-4, is a beta-lactamase-resistant, cephalosporin antibiotic which shows activity against gram-positive and gram-negative bacteria. Learn more.

Formula: C₁₆H₁₆N₅NaO₇S₂

Color and Shape: Powder

Molecular weight: 477.44

Ref: 02-J62690

Cefotaxime Sodium

CAS: 64485-93-4

Color and Shape: Neat

Ref: 61-FOR0414.00

CEFOTAXIME SODIUM CRS

CAS: 64485-93-4

CEFOTAXIME SODIUM CRS

Formula: C₁₆H₁₆N₅NaO₇S₂

Color and Shape: White. Yellow. Powder.

Molecular weight: 477.4473

Ref: 41-C0685000

CEFOTAXIME FOR PEAK IDENTIFICATION CRS

CAS: 64485-93-4

CEFOTAXIME FOR PEAK IDENTIFICATION CRS

Formula: C₁₆H₁₆N₅NaO₇S₂

Molecular weight: 477.4473

Ref: 41-Y0000506

Cefotaxime Sodium

CAS: 64485-93-4

Antibiotics nesoi

Formula: C₁₆H₁₆N₅NaO₇S₂

Color and Shape: Off-White Light Yellow Crystalline Powder

Molecular weight: 477.03888

Ref: 45-1097909

sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅NaO₇S₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 477.4473

Ref: IN-DA00IBDB

Cefotaxime sodium

CAS: 64485-93-4

Cefotaxime: 3rd-gen cephalosporin antibiotic, broad-spectrum, similar to ceftriaxone, sold as Claforan.

Formula: C₁₆H₁₆N₅NaO₇S₂

Purity: 99.52%

Color and Shape: White To Pale Yellow Crystalline Powder

Molecular weight: 477.44

Ref: TM-T0911

Cefotaxime sodium

CAS: 64485-93-4

Cefotaxime sodium

Purity: ≥98%

Molecular weight: 477.44g/mol

Ref: 54-BUP16891

Cefotaxime (100mg/ml)

CAS: 64485-93-4

Cefotaxime (100mg/ml)

Color and Shape: Solution

Molecular weight: 477.4473g/mol

Ref: 54-BIG1027

Cefotaxime Sodium Salt

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅O₇S₂·Na

Color and Shape: White To Off-White Solid

Molecular weight: 454.45 22.99

Ref: 4Z-C-106001

Cefotaxime sodium salt

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅NaO₇S₂

Purity: 916 - 964 μg/mg (C16H17N5O7S2, dried basis)

Color and Shape: White, off-white or pale yellow crystalline powder

Molecular weight: 477.40

Ref: 7W-GA3583

Cefotaxime sodium

CAS: 64485-93-4

Cefotaxime sodium

Formula: C₁₆H₁₆N₅O₇S₂·Na

Color and Shape: White To Yellow Powder

Molecular weight: 477.4473g/mol

Ref: 54-BIC0111

Cefotaxime sodium

Controlled Product

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅O₇S₂·Na

Color and Shape: Neat

Molecular weight: 477.45

Ref: 04-C11064400

Cefotaxime Sodium

Controlled Product

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅O₇S₂·Na

Color and Shape: Neat

Molecular weight: 477.45

Ref: 86-MM0414.00

Cefotaxime Sodium

Controlled Product

CAS: 64485-93-4

Applications Broad spectrum third generation cephalosporin antibiotic. The name Cefotaxime applies to the isomer having a syn-methoxy imino group.
References Wise, R., et al.: Antimicrob. Agents Chemother., 14, 807 (1978), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 11, 139 (1982),

Formula: C₁₆H₁₆N₅O₇S₂·Na

Color and Shape: White

Molecular weight: 477.45

Ref: TR-C242950

Cefotaxime-d3

Controlled Product

CAS: 64485-93-4

Applications Broad spectrum third generation cephalosporin antibiotic.
References Wise, R., et al.: Antimicrob. Agents Chemother., 14, 807 (1978), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 11, 139 (1982),

Formula: C₁₆H₁₄D₃N₅O₇S₂

Color and Shape: Neat

Molecular weight: 458.48

Ref: TR-C242952

Cefotaxime sodium

CAS: 64485-93-4

Cefotaxime sodium is a broad-spectrum cephalosporin antibiotic, which is a semisynthetic derivative of cephalosporin C obtained from the mold Acremonium. This compound functions by inhibiting bacterial cell wall synthesis, which it achieves through binding to and deactivating penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. This action prevents the cross-linking of peptidoglycan chains, leading to cell lysis and bacterial death, primarily affecting rapidly dividing cells.

Formula: C₁₆H₁₇N₅O₇S₂·Na

Color and Shape: White Powder

Molecular weight: 478.46 g/mol

Ref: 3D-AC11346

Cephotaxime Sodium Salt (CFT) for cell culture, 916-964ug/mg, Endotoxin (BET) 0.20EU/mg

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅NaO₇S₂

Purity: 916 - 964 µg/mg

Color and Shape: Off-white to pale yellow, Crystalline powder, Clear

Molecular weight: 477.45

Ref: SR-81642

Cephotaxime Sodium Salt (CFT), 916-964ug/mg

CAS: 64485-93-4

Formula: C₁₆H₁₆N₅NaO₇S₂

Purity: 916 - 964 µg/mg (on dry basis)

Color and Shape: Off-white to pale yellow, Crystalline powder, Clear

Molecular weight: 477.45

Ref: SR-19660