CAS 645-05-6

Altretamine

Description:

Altretamine, also known by its chemical name, hexamethylmelamine, is an organic compound primarily used as a chemotherapeutic agent in the treatment of certain types of cancer, particularly ovarian cancer. It is classified as an alkylating agent, which means it works by interfering with the DNA of cancer cells, ultimately leading to cell death. Altretamine is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Its chemical formula is C6H12N4, and it features a structure that includes a melamine core with methyl groups attached. The compound is administered orally and is known for its relatively mild side effect profile compared to other chemotherapy agents, although it can still cause nausea, vomiting, and hematological toxicity. Altretamine's mechanism of action involves the formation of reactive intermediates that bind to DNA, disrupting replication and transcription processes in rapidly dividing cancer cells. As with all chemotherapeutic agents, its use is carefully monitored in clinical settings to balance efficacy with potential adverse effects.

Formula: C₉H₁₈N₆

InChI: InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3

InChI key: InChIKey=UUVWYPNAQBNQJQ-UHFFFAOYSA-N

SMILES: N(C)(C)C=1N=C(N(C)C)N=C(N(C)C)N1

Synonyms:

• 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl-
• 1,3,5-Triazine-2,4,6-triamine, N2,N2,N4,N4,N6,N6-hexamethyl-
• 1,3,5-Triazine-2,4,6-triamine, N²,N²,N⁴,N⁴,N⁶,N⁶-hexamethyl-
• 1,3,5-Tris(Dimethylamino)-S-Triazine
• 2,4,6-Tris(Dimethylamino)-S-Triazin
• 2,4,6-Tris(Dimethylamino)-s-triazine
• 2,4,6-Tris(dimethylamino)-1,3,5-triazine
• 2,4,6-Tris-(Dimethylamino)-1,3,5-Triazin
• 2-N,2-N,4-N,4-N,6-N,6-N-Hexamethyl-1,3,5-triazine-2,4,6-triamine
• 5-Triazine-2,4,6-Triamine,N,N,N',N',N'',N''-Hexamethyl-3
• Aitretamine
• Altretamin
• Altretamina
• Ent 50852
• Ent050852
• HMM
• Hemel
• Hexalen
• Hexamethylmelamine
• Hexylen
• Melamine, hexamethyl-
• N²,N²,N⁴,N⁴,N⁶,N⁶-Hexamethyl-1,3,5-triazine-2,4,6-triamine
• Nsc 13875

Altretamine

CAS: 645-05-6

Compounds (excluding melamine) containing an unfused tr

Formula: C₉H₁₈N₆

Color and Shape: Powder

Molecular weight: 210.15929

Ref: 45-1017105

2,4,6-Tris(dimethylamino)-1,3,5-triazine

CAS: 645-05-6

Formula: C₉H₁₈N₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 210.2794

Ref: IN-DA0034G8

Altretamine

CAS: 645-05-6

Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.

Formula: C₉H₁₈N₆

Purity: 99.54%

Color and Shape: Less Crystalline Solid Insoluble In Water (Ntp 1992) Physical Description Colorless Crystalline Solid Insoluble In Water (Ntp 1992)

Molecular weight: 210.28

Ref: TM-T1241

Altretamine

CAS: 645-05-6

Altretamine

Purity: ≥98%

Molecular weight: 210.28g/mol

Ref: 54-BUP15919

Altretamine

CAS: 645-05-6

Formula: C₉H₁₈N₆

Molecular weight: 210.28

Ref: 7W-GP0509

N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-Triazine-2,4,6-Triamine

CAS: 645-05-6

N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-Triazine-2,4,6-Triamine

Purity: 98%

Molecular weight: 210.28g/mol

Ref: 54-OR1014208

Altretamine

CAS: 645-05-6

Formula: C₉H₁₈N₆

Color and Shape: Neat

Molecular weight: 210.28

Ref: 04-C10144200

Altretamine

CAS: 645-05-6

Formula: C₉H₁₈N₆

Molecular weight: 210.29

Ref: 4Z-A-293001

Altretamine

Controlled Product

CAS: 645-05-6

Applications An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic.
References Chang, S.C., et al.: Science, 144, 57 (1964), Ames, M.M., et al.: Cancer Res., 39, 5016 (1979), D’Incalci, M., et al.: Br. J. Cancer, 41, 630 (1980),

Formula: C₉H₁₈N₆

Color and Shape: White Crystalline Powder

Molecular weight: 210.28

Ref: TR-A575765

Altretamine

CAS: 645-05-6

Alkylating agent; cytotoxic; antineoplastic

Formula: C₉H₁₈N₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 210.28 g/mol

Ref: 3D-FA17334

ALTRETAMINE

CAS: 645-05-6

Purity: 97%

Molecular weight: 210.2850037

Ref: 10-F825791