CAS 645-05-6: Altretamine

Description: Altretamine, also known by its chemical name, hexamethylmelamine, is an organic compound primarily used as a chemotherapeutic agent in the treatment of certain types of cancer, particularly ovarian cancer. It is classified as an alkylating agent, which means it works by interfering with the DNA of cancer cells, ultimately leading to cell death. Altretamine is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Its chemical formula is C6H12N4, and it features a structure that includes a melamine core with methyl groups attached. The compound is administered orally and is known for its relatively mild side effect profile compared to other chemotherapy agents, although it can still cause nausea, vomiting, and hematological toxicity. Altretamine's mechanism of action involves the formation of reactive intermediates that bind to DNA, disrupting replication and transcription processes in rapidly dividing cancer cells. As with all chemotherapeutic agents, its use is carefully monitored in clinical settings to balance efficacy with potential adverse effects.

Formula: C₉H₁₈N₆

InChI: InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3

InChI key: InChIKey=UUVWYPNAQBNQJQ-UHFFFAOYSA-N

SMILES: N=1C(=NC(=NC1N(C)C)N(C)C)N(C)C

Synonyms:

• 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl-
• 1,3,5-Triazine-2,4,6-triamine, N2,N2,N4,N4,N6,N6-hexamethyl-
• 1,3,5-Triazine-2,4,6-triamine, N²,N²,N⁴,N⁴,N⁶,N⁶-hexamethyl-
• 1,3,5-Tris(Dimethylamino)-S-Triazine
• 2,4,6-Tris(Dimethylamino)-S-Triazin
• 2,4,6-Tris(Dimethylamino)-s-triazine
• 2,4,6-Tris(dimethylamino)-1,3,5-triazine
• 2,4,6-Tris-(Dimethylamino)-1,3,5-Triazin
• 2-N,2-N,4-N,4-N,6-N,6-N-Hexamethyl-1,3,5-triazine-2,4,6-triamine
• 5-Triazine-2,4,6-Triamine,N,N,N',N',N'',N''-Hexamethyl-3
• Aitretamine
• Altretamin
• Altretamina
• Ent 50852
• Ent050852
• HMM
• Hemel
• Hexalen
• Hexamethylmelamine
• Hexylen
• Melamine, hexamethyl-
• N²,N²,N⁴,N⁴,N⁶,N⁶-Hexamethyl-1,3,5-triazine-2,4,6-triamine
• Nsc 13875
• N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine

Altretamine

CAS: 645-05-6

Compounds (excluding melamine) containing an unfused tr

• Formula: C₉H₁₈N₆
• Color and Shape: Powder
• Molecular weight: 210.15929

2,4,6-Tris(dimethylamino)-1,3,5-triazine

CAS: 645-05-6

• Formula: C₉H₁₈N₆
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 210.2794

Altretamine

CAS: 645-05-6

Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.

• Formula: C₉H₁₈N₆
• Purity: 99.54%
• Color and Shape: Less Crystalline Solid Insoluble In Water (Ntp 1992) Physical Description Colorless Crystalline Solid Insoluble In Water (Ntp 1992)
• Molecular weight: 210.28

Altretamine

CAS: 645-05-6

• Purity: 99.83%
• Molecular weight: 210.28g/mol

Altretamine

CAS: 645-05-6

• Formula: C₉H₁₈N₆
• Molecular weight: 210.28

N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-Triazine-2,4,6-Triamine

CAS: 645-05-6

• Purity: 98%+
• Molecular weight: 210.28g/mol

Altretamine

CAS: 645-05-6

• Formula: C₉H₁₈N₆
• Color and Shape: Neat
• Molecular weight: 210.28

Altretamine

CAS: 645-05-6

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₉H₁₈N₆
• Color and Shape: White to almost white, Powder
• Molecular weight: 210.29

Altretamine

CAS: 645-05-6

• Formula: C₉H₁₈N₆
• Molecular weight: 210.29

Altretamine

CAS: 645-05-6

Applications An antitumor agent which also acts as a chemosterilant for male houseflies and other …

• Formula: C₉H₁₈N₆
• Color and Shape: White Crystalline Powder
• Molecular weight: 210.28

Altretamine

CAS: 645-05-6

Alkylating agent; cytotoxic; antineoplastic

• Formula: C₉H₁₈N₆
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 210.28 g/mol