CAS 645-05-6
:Altretamine
Description:
Altretamine, also known by its chemical name, hexamethylmelamine, is an organic compound primarily used as a chemotherapeutic agent in the treatment of certain types of cancer, particularly ovarian cancer. It is classified as an alkylating agent, which means it works by interfering with the DNA of cancer cells, ultimately leading to cell death. Altretamine is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Its chemical formula is C6H12N4, and it features a structure that includes a melamine core with methyl groups attached. The compound is administered orally and is known for its relatively mild side effect profile compared to other chemotherapy agents, although it can still cause nausea, vomiting, and hematological toxicity. Altretamine's mechanism of action involves the formation of reactive intermediates that bind to DNA, disrupting replication and transcription processes in rapidly dividing cancer cells. As with all chemotherapeutic agents, its use is carefully monitored in clinical settings to balance efficacy with potential adverse effects.
Formula:C9H18N6
InChI:InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3
InChI key:InChIKey=UUVWYPNAQBNQJQ-UHFFFAOYSA-N
SMILES:N(C)(C)C=1N=C(N(C)C)N=C(N(C)C)N1
Synonyms:- 1,3,5-Triazine-2,4,6-triamine, N,N,N',N',N'',N''-hexamethyl-
- 1,3,5-Triazine-2,4,6-triamine, N2,N2,N4,N4,N6,N6-hexamethyl-
- 1,3,5-Triazine-2,4,6-triamine, N<sup>2</sup>,N<sup>2</sup>,N<sup>4</sup>,N<sup>4</sup>,N<sup>6</sup>,N<sup>6</sup>-hexamethyl-
- 1,3,5-Tris(Dimethylamino)-S-Triazine
- 2,4,6-Tris(Dimethylamino)-S-Triazin
- 2,4,6-Tris(Dimethylamino)-s-triazine
- 2,4,6-Tris(dimethylamino)-1,3,5-triazine
- 2,4,6-Tris-(Dimethylamino)-1,3,5-Triazin
- 2-N,2-N,4-N,4-N,6-N,6-N-Hexamethyl-1,3,5-triazine-2,4,6-triamine
- 5-Triazine-2,4,6-Triamine,N,N,N',N',N'',N''-Hexamethyl-3
- Aitretamine
- Altretamin
- Altretamina
- Ent 50852
- Ent050852
- HMM
- Hemel
- Hexalen
- Hexamethylmelamine
- Hexylen
- Melamine, hexamethyl-
- N<sup>2</sup>,N<sup>2</sup>,N<sup>4</sup>,N<sup>4</sup>,N<sup>6</sup>,N<sup>6</sup>-Hexamethyl-1,3,5-triazine-2,4,6-triamine
- Nsc 13875
- See more synonyms
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Found 12 products.
Altretamine
CAS:Compounds (excluding melamine) containing an unfused trFormula:C9H18N6Color and Shape:PowderMolecular weight:210.15929N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-Triazine-2,4,6-Triamine
CAS:N2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-Triazine-2,4,6-TriamineFormula:C9H18N6Purity:98%Color and Shape:SolidMolecular weight:210.282,4,6-Tris(dimethylamino)-1,3,5-triazine
CAS:Formula:C9H18N6Purity:97%Color and Shape:SolidMolecular weight:210.2794Altretamine
CAS:Altretamine (ENT-50852) is an alkylating agent with antineoplastic activity.Formula:C9H18N6Purity:99.54%Color and Shape:Less Crystalline Solid Insoluble In Water (Ntp 1992) Physical Description Colorless Crystalline Solid Insoluble In Water (Ntp 1992)Molecular weight:210.28Altretamine
CAS:Controlled ProductApplications An antitumor agent which also acts as a chemosterilant for male houseflies and other insects. Antineoplastic.
References Chang, S.C., et al.: Science, 144, 57 (1964), Ames, M.M., et al.: Cancer Res., 39, 5016 (1979), D’Incalci, M., et al.: Br. J. Cancer, 41, 630 (1980),Formula:C9H18N6Color and Shape:NeatMolecular weight:210.28Altretamine
CAS:Alkylating agent; cytotoxic; antineoplastic
Formula:C9H18N6Purity:Min. 95%Color and Shape:PowderMolecular weight:210.28 g/mol
