CAS 64657-21-2

Isoforskolin

Description:

Isoforskolin, with the CAS number 64657-21-2, is a chemical compound derived from the plant Coleus forskohlii, which is known for its traditional use in herbal medicine. It is a labdane diterpenoid, characterized by its unique bicyclic structure that includes a fused cyclopentane and cyclohexane ring system. Isoforskolin exhibits various biological activities, including potential anti-inflammatory, anti-cancer, and cardiovascular effects, making it a subject of interest in pharmacological research. The compound is known to activate adenylate cyclase, leading to increased levels of cyclic AMP (cAMP) in cells, which plays a crucial role in various signaling pathways. Isoforskolin is typically studied for its therapeutic potential, particularly in metabolic disorders and weight management. Its solubility properties can vary, and it is often analyzed using techniques such as chromatography. As with many natural compounds, further research is necessary to fully understand its mechanisms of action and potential applications in medicine.

Formula: C₂₂H₃₄O₇

InChI: InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(28-12(2)23)17(26)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1

InChI key: InChIKey=CLOQVZCSBYBUPB-KGGHGJDLSA-N

SMILES: C[C@@]12[C@]3(O)[C@@](C)([C@@H](O)[C@@H](OC(C)=O)[C@]1(C(C)(C)CC[C@@H]2O)[H])O[C@](C=C)(C)CC3=O

Synonyms:

• (1α,5α,6β,7β)-6-(Acetyloxy)-8,13-epoxy-1,7,9-trihydroxylabd-14-en-11-one
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(Acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
• 1H-Naphtho[2,1-b]pyran-1-one, 6-(acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-
• 1H-Naphtho[2,1-b]pyran-1-one, 6-(acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, [3R-(3α,4aβ,5β,6β,6aα,10α,10aβ,10bα)]-
• 6β-ACETOXY-8,13-EPOXY-1α,7β,9α-TRIHYDROXY-LABD-14-EN-11-ONE
• 6β-Acetoxy-8,13-epoxy-1α,7β,9α-trihydroxylabd-14-en-11-one
• Coleonol B
• Excolabdone C
• Isoforskolin

(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6-(Acetyloxy)-3-ethenyldodecahydro-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one

CAS: 64657-21-2

Formula: C₂₂H₃₄O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 410.5012

Ref: IN-DA0039YI

Isoforskolin

CAS: 64657-21-2

Formula: C₂₂H₃₄O₇

Molecular weight: 410.51

Ref: 7W-GY7548

Isoforskolin

CAS: 64657-21-2

Isoforskolin

Purity: ≥98%

Molecular weight: 410.5g/mol

Ref: 54-BUP00563

Isoforskolin

CAS: 64657-21-2

Isoforskolin, from Coleus forskohlii, lowers TNF-α, IL-1β, IL-6, IL-8; studied for Lyme arthritis treatment.

Formula: C₂₂H₃₄O₇

Purity: 99.87%

Color and Shape: Solid

Molecular weight: 410.5

Ref: TM-TN1520

Isoforskolin

CAS: 64657-21-2

Formula: C₂₂H₃₄O₇

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 410.507

Ref: BP-BP1546

Isoforskolin

CAS: 64657-21-2

Formula: C₂₂H₃₄O₇

Molecular weight: 410.51

Ref: 4Z-F-238003

Isoforskolin

CAS: 64657-21-2

Oxygen-heterocyclic compound

Formula: C₂₂H₃₄O₇

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 410.51

Ref: 5G-82566

Isoforskolin

CAS: 64657-21-2

Isoforskolin is a forskolin derivative diterpenoid, which is extracted from the roots of *Coleus forskohlii*. This bioactive compound acts primarily by stimulating adenylate cyclase activity, leading to increased levels of cyclic adenosine monophosphate (cAMP) within cells. The elevated cAMP serves as a secondary messenger that can modulate various physiological responses, including lipolysis and vasodilation.

Formula: C₂₂H₃₄O₇

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 410.5 g/mol

Ref: 3D-FI74121