CAS 64887-14-5

Urapidil hydrochloride

Description:

Urapidil hydrochloride is a pharmaceutical compound primarily used as an antihypertensive agent. It functions by acting as an alpha-1 adrenergic receptor antagonist and a serotonin receptor agonist, which helps to lower blood pressure by promoting vasodilation and reducing peripheral resistance. The substance is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. Urapidil is known for its rapid onset of action and is often used in acute settings to manage hypertension. In terms of physical characteristics, it is usually presented as a white to off-white crystalline powder, which is soluble in water and has a specific melting point range. The compound is generally well-tolerated, though it may cause side effects such as dizziness, fatigue, or gastrointestinal disturbances in some patients. As with any medication, it is essential to use Urapidil hydrochloride under medical supervision to ensure safety and efficacy.

Formula: C₂₀H₃₀ClN₅O₃

InChI: InChI=1/C20H29N5O3.ClH/c1-22-18(15-19(26)23(2)20(22)27)21-9-6-10-24-11-13-25(14-12-24)16-7-4-5-8-17(16)28-3;/h4-5,7-8,15,21H,6,9-14H2,1-3H3;1H

SMILES: Cn1c(cc(=O)n(C)c1=O)NCCCN1CCN(CC1)c1ccccc1OC.Cl

Synonyms:

• 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil hydrochloride
• 6-({3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione hydrochloride (1:1)
• URAPIDIL HCL
• 6-[[3-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]PROPYL]AMINO]-1,3-DIMETHYL-2,4(1H,3H)-PYRIMIDINEDIONE HYDROCHLORIDE
• 6[[3-[4-(O-METHOXYPHENYL)-1-PIPERAZINYL]PROPYL]AMINO]-1,3-DIMETHYLURACIL HYDROCHLORIDE
• 6-[[3-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]PROPYL]AMINO]-1,3-DIMETHYL-2,4(1H,3H)-PYRIMIDINEDIONE
• 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethylpyrimidine-2,4-dione hydrochloride
• 6-[[3-[4-(2-methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione,hydrochloride (1:1)
• 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethyl-pyrimidine-2,4-dione hydrochloride
• URAPIDIL HYDROCHLORIDE A1 ADRENOCEPTOR A NTAG
• 6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propylamino]-1,3-dimethyl-pyrimidine-2,4-quinone hydrochloride

Urapidil hydrochloride

CAS: 64887-14-5

Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.

Formula: C₂₀H₂₉N₅O₃·HCl

Purity: 99.58%

Color and Shape: Solid

Molecular weight: 423.94

Ref: TM-T0088

Urapidil (hydrochloride)

CAS: 64887-14-5

Formula: C₂₀H₃₀ClN₅O₃

Purity: 99%

Color and Shape: Solid

Molecular weight: 423.9369

Ref: IN-DA006SA1

Urapidil Hydrochloride

CAS: 64887-14-5

Urapidil Hydrochloride

Formula: C₂₀H₃₀ClN₅O₃

Purity: 99%

Molecular weight: 423.94

Ref: 54-OR1025559

Urapidil hydrochloride

CAS: 64887-14-5

Urapidil hydrochloride

Formula: C₂₀H₂₉N₅O₃·HCl

Purity: ≥98%

Molecular weight: 423.94

Ref: 54-BUP16941

Urapidil HCl

CAS: 64887-14-5

Formula: C₂₀H₂₉N₅O₃·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 387.48 36.46

Ref: 4Z-U-071

Urapidil hydrochloride

CAS: 64887-14-5

Formula: C₂₀H₂₉N₅O₃·HCl

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 423.94

Ref: 7W-GP1109

Urapidil Hydrochloride

CAS: 64887-14-5

Applications α1-Adrenergic antagonist; derivative of Uracil (U801000). Antihypertensive.
References Eltze, M., et al.: Eur. J. Pharmacol., 59, 1 (1979), Barankay, A., et al.: Arzneim.-Forsch., 31, 849 (1981), Belz, G.G., et al.: Clin. Pharmacol. Ther., 37, 48 (1985),

Formula: C₂₀H₂₉N₅O₃·ClH

Color and Shape: Neat

Molecular weight: 423.94

Ref: TR-U815400

Urapidil hydrochloride

CAS: 64887-14-5

Purity: 99%

Molecular weight: 423.94

Ref: 10-F979484

Urapidil Hydrochloride

CAS: 64887-14-5

Formula: C₂₀H₂₉N₅O₃HCl

Molecular weight: 387.48 : 36.46

Ref: ST-EA-CP-U2017