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CAS 65-29-2

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Gallamine triethiodide

Description:
Gallamine triethiodide is a quaternary ammonium compound primarily used as a neuromuscular blocking agent in anesthesia. It is characterized by its ability to induce muscle relaxation during surgical procedures by blocking the transmission of nerve impulses to skeletal muscles. The compound is typically presented as a white to off-white crystalline powder, soluble in water, which facilitates its administration in clinical settings. Gallamine triethiodide acts by competing with acetylcholine at the neuromuscular junction, leading to paralysis of voluntary muscles. Its pharmacological effects can be reversed with anticholinesterase agents, which increase the availability of acetylcholine. The compound has a relatively long duration of action compared to other neuromuscular blockers, making it suitable for certain surgical applications. However, it may also have side effects, including cardiovascular effects and potential allergic reactions. As with all neuromuscular blockers, careful monitoring of respiratory function is essential during its use.
Formula:C30H60N3O3·3I
InChI:InChI=1S/C30H60N3O3.3HI/c1-10-31(11-2,12-3)22-25-34-28-20-19-21-29(35-26-23-32(13-4,14-5)15-6)30(28)36-27-24-33(16-7,17-8)18-9;;;/h19-21H,10-18,22-27H2,1-9H3;3*1H/q+3;;;/p-3
InChI key:InChIKey=REEUVFCVXKWOFE-UHFFFAOYSA-K
SMILES:O(CC[N+](CC)(CC)CC)C1=C(OCC[N+](CC)(CC)CC)C=CC=C1OCC[N+](CC)(CC)CC.[I-]
Synonyms:
  • 1, 2, 3-Tris (2'-(triethylammonium) ethoxy) benzenetriiodide
  • 1,2,3-Tri(β-diethylaminoethoxy)benzene triethiodide
  • 1,2,3-Tris(2-diethylaminoethoxy)benzene triethiodide
  • 1,2,3-Tris(2-diethylaminoethoxy)benzene tris(ethyliodide)
  • 1,2,3-Tris(2-triethylammonium ethoxy)benzene triiodide
  • 1,2,3-Tris(diethylaminoethoxy)benzene triethiodide
  • 3697 Rp
  • Ammonium, [v-phenenyltris(oxyethylene)]tris[triethyl-, triiodide
  • Benzcurine iodide
  • Ethanaminium, 2,2',2''-[1,2,3-benzenetriyltris(oxy)]tris[N,N,N-triethyl-, iodide (1:3)
  • See more synonyms
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