CAS 65002-17-7

bucillamine

Description:

Bucillamine is a synthetic compound primarily used as a disease-modifying antirheumatic drug (DMARD) in the treatment of rheumatoid arthritis. It is classified as a thiol-containing compound, which contributes to its mechanism of action by modulating immune responses and exhibiting anti-inflammatory properties. Bucillamine is known for its ability to reduce joint inflammation and damage associated with autoimmune conditions. The substance has a relatively low molecular weight and is soluble in water, which facilitates its absorption and bioavailability in the body. Its chemical structure includes a dithiol moiety, which is significant for its reactivity and therapeutic effects. Bucillamine is generally well-tolerated, but like any medication, it may have side effects, including gastrointestinal disturbances and potential liver toxicity. Monitoring is essential during treatment to manage any adverse reactions. Overall, bucillamine represents an important option in the pharmacological management of chronic inflammatory diseases.

Formula: C₇H₁₃NO₃S₂

InChI: InChI=1/C7H13NO3S2/c1-7(2,13)6(11)8-4(3-12)5(9)10/h4,12-13H,3H2,1-2H3,(H,8,11)(H,9,10)/t4-/m0/s1

InChI key: InChIKey=VUAFHZCUKUDDBC-BYPYZUCNSA-N

SMILES: [C@@H](NC(C(C)(C)S)=O)(C(O)=O)CS

Synonyms:

• (2R)-2-(2-Methyl-2-sulfanylpropanamido)-3-sulfanylpropanoic acid
• (R)-3-Mercapto-2-(2-mercapto-2-methylpropanamido)propanoic acid
• <span class="text-smallcaps">L</span>-Cysteine, N-(2-mercapto-2-methyl-1-oxopropyl)-
• De 019
• N-(2-Mercapto-2-methyl-1-oxopropyl)-<span class="text-smallcaps">L</span>-cysteine
• N-(2-Mercapto-2-methylpropanoyl)-<span class="text-smallcaps">L</span>-cysteine
• N-(2-Mercapto-2-methylpropionyl)-<span class="text-smallcaps">L</span>-cysteine
• N-(2-Mercaptoisobutyryl)cysteine
• N-(2-methyl-2-sulfanylpropanoyl)-L-cysteine
• N-(2-methyl-2-sulfanylpropanoyl)cysteine
• Rimatil
• Sa 96
• Thiobutarit
• Tiobutarit
• L-Cysteine, N-(2-mercapto-2-methyl-1-oxopropyl)-
• N-(2-Mercapto-2-methylpropionyl)-L-cysteine
• N-(2-Mercapto-2-methylpropanoyl)-L-cysteine
• N-(2-Mercapto-2-methyl-1-oxopropyl)-L-cysteine
• sa96
• BUCILLAMINE
• n-(2-mercapto-2-methyl-1-oxopropyl)-l-cystein

(2R)-2-(2-methyl-2-sulfanylpropanamido)-3-sulfanylpropanoic acid

CAS: 65002-17-7

Formula: C₇H₁₃NO₃S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 223.3130

Ref: IN-DA00EAFM

Bucillamine

CAS: 65002-17-7

Bucillamine

Purity: ≥98%

Molecular weight: 223.31g/mol

Ref: 54-BUP11814

Bucillamine-d6

CAS: 65002-17-7

Formula: C₇H₇D₆NO₃S₂

Color and Shape: White To Off-White Solid

Molecular weight: 229.34

Ref: 4Z-B-067002

Bucillamine

CAS: 65002-17-7

Formula: C₇H₁₃NO₃S₂

Purity: ≥ 95.0%

Color and Shape: White to off-white or pale yellow powder

Molecular weight: 223.31

Ref: 7W-GP6149

(R)-3-Mercapto-2-(2-Mercapto-2-Methylpropanamido)Propanoic Acid

CAS: 65002-17-7

(R)-3-Mercapto-2-(2-Mercapto-2-Methylpropanamido)Propanoic Acid

Purity: 98%

Molecular weight: 223.31g/mol

Ref: 54-OR1008508

Bucillamine

CAS: 65002-17-7

Formula: C₇H₁₃NO₃S₂

Molecular weight: 223.31

Ref: 4Z-B-067001

Bucillamine

Controlled Product

CAS: 65002-17-7

Stability Unstable in Solution, Air Sensitive
Applications An antirheumatic agent.
References Masutani, K., et al.: Clin. Nephrol., 70, 464 (2008), Kobata, Y., et al.: Modern Rheumatol., 19, 629 (2009), Oki, K., et al.: Inflam. Res., 58, 571 (2009),

Formula: C₇H₁₃NO₃S₂

Color and Shape: Neat

Molecular weight: 223.31

Ref: TR-B689375

Bucillamine

CAS: 65002-17-7

Potential treatment for gout and rheumatoid arthritis

Formula: C₇H₁₃NO₃S₂

Purity: Min. 95 Area-%

Color and Shape: White Slightly Yellow Powder

Molecular weight: 223.32 g/mol

Ref: 3D-FB19345

Bucillamine

CAS: 65002-17-7

Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.

Formula: C₇H₁₃NO₃S₂

Purity: 99.47%

Color and Shape: Solid

Molecular weight: 223.31

Ref: TM-T21334