CAS 65646-68-6
:Fenretinide
Description:
Fenretinide, also known as N-(4-hydroxyphenyl)retinamide, is a synthetic retinoid that is primarily studied for its potential therapeutic effects in cancer treatment and prevention. It is characterized by its ability to modulate gene expression and influence cellular differentiation and apoptosis, making it a subject of interest in oncology research. Fenretinide exhibits a unique mechanism of action, distinct from other retinoids, as it does not activate retinoic acid receptors in the same manner. Instead, it is thought to exert its effects through the induction of oxidative stress and the modulation of various signaling pathways. The compound is typically administered in a non-toxic dosage form, and its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are crucial for its efficacy. Fenretinide has shown promise in clinical trials for certain types of cancer, particularly breast cancer, and is being investigated for its potential use in other malignancies. Its safety profile and side effects are also important considerations in ongoing research.
Formula:C26H33NO2
InChI:InChI=1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
InChI key:InChIKey=AKJHMTWEGVYYSE-FXILSDISSA-N
SMILES:C(=C/C(=C/C=C/C(=C/C(NC1=CC=C(O)C=C1)=O)/C)/C)\C=2C(C)(C)CCCC2C
Synonyms:- (4-Hydroxyphenyl)retinamide
- 15-[(4-Hydroxyphenyl)Amino]Retinal
- 4-Hpr
- Fenretinide
- Mk 4016
- N-(4-hydroxyphenyl)all-trans retinamide
- RII retinamide
- Retinamide, N-(4-hydroxyphenyl)-
- Retinoic acid p-hydroxyanilide
- Retinoic acid p-hydroxyphenylamide
- Ro 22-4667
- all-trans-4′-Hydroxyretinanilide
- all-trans-N-(4-hydroxyphenyl)retinamide
- See more synonyms
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Found 12 products.
all-trans-N-(4-Hydroxyphenyl)retinamide
CAS:Formula:C26H33NO2Purity:>98.0%(HPLC)Color and Shape:White to Yellow to Orange powder to crystalMolecular weight:391.56N-(4-Hydroxyphenyl)retinamide
CAS:Formula:C26H33NO2Purity:98%Color and Shape:SolidMolecular weight:391.5457Ref: 54-BUP10695
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire200mgTo inquireFenretinide
CAS:FenretinideFormula:C26H33NO2Purity:>99%Color and Shape: yellow solidMolecular weight:391.55g/molFenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Formula:C26H33NO2Purity:98% - 99.68%Color and Shape:Yellow PowderMolecular weight:391.55Fenretinide
CAS:Formula:C26H33NO2Purity:≥ 98.0%Color and Shape:Yellow to yellow-orange powderMolecular weight:391.55Fenretinide
CAS:Controlled Product<p>Stability Light Sensitive - Protect from Light Exposure<br>Applications Fenretinide (4-HPR) is a synthetic retinoid deriverative. 4-HBR is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.A synthetic analog of Vitamin A.<br>References Marth, C., et al.:J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)<br></p>Formula:C26H33NO2Color and Shape:NeatMolecular weight:391.55Fenretinide
CAS:<p>Modulator of RBP protein; activator of sphingomyelinase; pro-apoptotic</p>Formula:C26H33NO2Purity:Min. 95%Color and Shape:Yellow SolidMolecular weight:391.55 g/molFenretinide-d4
CAS:Controlled Product<p>Applications Fenretinide-d4, is the labeled analogue of Fenretinide (F250000), which is a synthetic analog of Vitamin A.<br>References Marth, C., et al.: J. Nat. Cancer Inst., 75, 871 (1985), Delia, D., et al.: Cancer Res., 53, 6036 (1993), Costa., A., et al.: Cancer Res., 54, Suppl., 2032s (1994), Decensi., A., et al.: Eur. J. Cancer Prev., 3, 377 (1994)<br></p>Formula:C26D4H29NO2Color and Shape:NeatMolecular weight:395.57
