CAS 657408-07-6

2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl

Description:

2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl is a phosphine ligand commonly used in organometallic chemistry and catalysis, particularly in transition metal complexes. This compound features a biphenyl backbone with methoxy substituents at the 2 and 6 positions, enhancing its solubility and steric properties. The dicyclohexylphosphino group provides strong donor characteristics, making it effective in stabilizing metal centers in catalytic reactions. The presence of bulky cyclohexyl groups contributes to its steric hindrance, which can influence the selectivity and reactivity of metal complexes. This ligand is often employed in cross-coupling reactions, such as Suzuki or Heck reactions, due to its ability to facilitate the formation of carbon-carbon bonds. Additionally, its unique structural features allow for the tuning of electronic properties, making it a valuable tool in the development of new catalytic systems. Overall, 2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl is recognized for its effectiveness in promoting various chemical transformations in synthetic organic chemistry.

Formula: C₂₆H₃₅O₂P

InChI: InChI=1S/C26H35O2P/c1-27-23-17-11-18-24(28-2)26(23)22-16-9-10-19-25(22)29(20-12-5-3-6-13-20)21-14-7-4-8-15-21/h9-11,16-21H,3-8,12-15H2,1-2H3

InChI key: InChIKey=VNFWTIYUKDMAOP-UHFFFAOYSA-N

SMILES: P(C1=C(C=CC=C1)C2=C(OC)C=CC=C2OC)(C3CCCCC3)C4CCCCC4

Synonyms:

• (2,6-Dimethoxy-1,1′-biphenyl-2-yl)dicyclohexylphosphine
• 2-(Dicyclohexylphosphino)-2′,6′-dimethoxy-1,1′-biphenyl
• 2-Dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl
• 2-Dicyclohexylphosphino-2',6'-dimethoxybipheny
• 2-Dicyclohexylphosphino-2′,6′-dimethoxybiphenyl
• Dicyclohexyl(2',6'-Dimethoxybiphenyl-2-Yl)Phosphane
• Dicyclohexyl(2′,6′-dimethoxy[1,1′-biphenyl]-2-yl)phosphine
• Dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine
• Dicyclohexyl({2-[(2,6-Dimethoxyphenyl)Methyl]Phenyl}Methyl)Phosphane
• Phosphine, dicyclohexyl(2′,6′-dimethoxy[1,1′-biphenyl]-2-yl)-
• S-Phos
• SPhos 97%
• 2-Dicyclohexylphosphino-2',6'-diMethoxy-1,1'-biphenyl,98% Sphos
• 2-DicyclohexylphosphiNA-2',6'-diMethoxybiphenyl
• Dicyclohexyl(2',6'-dimethoxybiphenyl-2-yl)phosphine
• 2-Dicyclohexylphosphino-2&acute
• REF DUPL: S-PHOS
• 2 - dicyclohexyl phosphine - 2 ', 6 '- diMethoxy - 1, 1' - two PCB
• S-Phos, ChemDose(R) tablets
• S-Phos impregnated tablets, ChemDose(R), S-Phos tablets, 2-Dicyclohexylphosphino-2μ,6μ-dimethoxybiphenyl impregnated tablets
• 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
• 6&acute
• 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl, min. 98%
• 98% SPhos
• 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl, 98+%
• 2-Dicyclohexylphosphino-2’,6’-dimethoxy-1,1’-biphenyl (S-Phos)
• S-PHOS, 2-Dicyclohexylphosphino-2,6-di-Methyloxy-1,1-biphenyl
• Phosphine,dicyclohexyl(2',6'-dimethoxy[1,1'-biphenyl]-2-yl)-
• 2-Dicyclohexylphosphino-2', 6-diMethoxybihenyl
• 2-DICYCLOHEXYLPHOSPHINO-2',6'-DIMETHOXY-1,1'-BIPHENYL, MIN. 98% S-PHOS
• 2-Dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl, min. 98%
• 2-(Dicyclohexylphosphanyl)-2',6'-dimethoxybiphenyl
• 2-Dicyclohexylphosphino-2',6'-diMethoxybiphenyl, 6'-diMethoxybiphenyl
• SPhos, >=98%
• 2-Dicyclohexylphosphino-2',6'-
• S-Phos, ChemDose? tablets
• -diMethoxybiphenyl
• Dicyclohexyl-[2-(2,6-dimethoxyphenyl)phenyl]phosphane
• Dicyclohexyl(2',6'-diMethoxy-[1,1'-biphenyl]-2-yl)phosphine

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

CAS: 657408-07-6

Formula: C₂₆H₃₅O₂P

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 410.54

Ref: 3B-D5036

2-Dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl, min. 98% SPhos

CAS: 657408-07-6

2-Dicyclohexylphosphino-2',6'-dimethoxy-1,1'-biphenyl, min. 98% SPhos

Formula: C₂₆H₃₅O₂P

Purity: min. 98%

Color and Shape: white xtl.

Molecular weight: 410.53

Ref: 08-15-1143

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

CAS: 657408-07-6

Formula: C₂₆H₃₅O₂P

Purity: 98%

Color and Shape: Solid

Molecular weight: 410.5287

Ref: IN-DA0033A9

2-(Dicyclohexylphosphanyl)-2',6'-dimethoxybiphenyl

CAS: 657408-07-6

2-(Dicyclohexylphosphanyl)-2',6'-dimethoxybiphenyl

Formula: C₂₆H₃₅O₂P

Purity: 98%

Color and Shape: white crystalline powder

Molecular weight: 410.53g/mol

Ref: 54-OR40584

2-Dicyclohexylphosphino-2'',6''-dimethoxybiphenyl

CAS: 657408-07-6

Formula: C₂₆H₃₅O₂P

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 410.54

Ref: 7W-GK5403

Dicyclohexyl(2′,6′-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine

CAS: 657408-07-6

Formula: C₂₆H₃₅O₂P

Purity: 98.0%

Color and Shape: Solid, Powder or Crysalline Powder or Solid or Chunks

Molecular weight: 410.538

Ref: 10-F078390

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl

CAS: 657408-07-6

2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl is a fluorescent chemical that has been used to study interactions of fatty acids and halides. It is also used in the synthesis of palladium complexes, which have been shown to be effective for hydrogenation reactions. 2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl can be synthesized from 2,6-dichlorobenzaldehyde and dicyclohexylphosphine by the addition of trifluoroacetic acid. The synthesis proceeds via a substitution reaction with methoxy groups on the aromatic ring. This product fluoresces under ultraviolet light at 351 nm.

Formula: C₂₆H₃₅O₂P

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 410.53 g/mol

Ref: 3D-FD31495

S-Phos

Controlled Product

CAS: 657408-07-6

Applications S-Phos is a catalyst that is used in the preparation of thiadiazoles as DGAT1 inhibitors with potential in metabolic diseases treatment.
References Mougenot, P., et la.: Bioorg. Med. Chem. Lett., 22, 2497 (2012);

Formula: C₂₆H₃₅O₂P

Color and Shape: Neat

Molecular weight: 410.53

Ref: TR-S681720

S-Phos (2-Dicyclohexylphosphino-2,6-Dimethoxybiphenyl) extrapure, 98%

CAS: 657408-07-6

Formula: C₂₆H₃₅O₂P

Purity: min.98%

Color and Shape: White, Crystalline powder

Molecular weight: 410.53

Ref: SR-77061