CAS 658084-64-1

(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide

Description:

The chemical substance known as (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide, with the CAS number 658084-64-1, is a synthetic organic compound characterized by its complex structure, which includes a propenamide backbone, a piperidine ring, and a pyridine moiety. This compound typically exhibits properties associated with amides, such as moderate solubility in polar solvents and potential biological activity due to its structural features. The presence of the benzoyl group suggests potential interactions with biological targets, making it of interest in medicinal chemistry. Its specific stereochemistry, indicated by the (2E) configuration, may influence its pharmacological properties and interactions with receptors or enzymes. As a result, this compound may be investigated for its therapeutic potential, particularly in areas related to neurological or psychiatric disorders, given the piperidine and pyridine components. However, detailed studies would be necessary to fully elucidate its properties, mechanisms of action, and potential applications in drug development.

Formula: C₂₄H₂₉N₃O₂

InChI: InChI=1S/C24H29N3O2/c28-23(12-11-21-8-6-15-25-19-21)26-16-5-4-7-20-13-17-27(18-14-20)24(29)22-9-2-1-3-10-22/h1-3,6,8-12,15,19-20H,4-5,7,13-14,16-18H2,(H,26,28)/b12-11+

InChI key: InChIKey=KPBNHDGDUADAGP-VAWYXSNFSA-N

SMILES: C(=O)(N1CCC(CCCCNC(/C=C/C=2C=CC=NC2)=O)CC1)C3=CC=CC=C3

Synonyms:

• (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide
• 2-Propenamide, N-[4-(1-benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-, (2E)-
• Apo 866
• Apo866
• Fk 866
• Fk866
• K 22.175

(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide

CAS: 658084-64-1

Formula: C₂₄H₂₉N₃O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 391.5060

Ref: IN-DA0036WT

(E)-Daporinad

CAS: 658084-64-1

(E)-Daporinad

Purity: ≥98%

Molecular weight: 391.51g/mol

Ref: 54-BUP13121

FK866

CAS: 658084-64-1

FK866

Molecular weight: 391.51g/mol

Ref: 54-BISN0147

FK866

CAS: 658084-64-1

Formula: C₂₄H₂₉N₃O₂

Molecular weight: 391.52

Ref: 4Z-L-182003

(E)-Daporinad

CAS: 658084-64-1

(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT） .Cost-effective and quality-assured.

Formula: C₂₄H₂₉N₃O₂

Purity: 98.44% - >99.99%

Color and Shape: Solid

Molecular weight: 391.51

Ref: TM-T2644

FK-866

CAS: 658084-64-1

Formula: C₂₄H₂₉N₃O₂

Purity: ≥ 98%

Color and Shape: White to yellow solid or powder (may liquefy easily)

Molecular weight: 391.5

Ref: 7W-GL7680

FK866

CAS: 658084-64-1

Applications FK866 is a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), that induces tumor cell apoptosis, and thus is a potential anticancer drug.
References Hasmann, M., Schemainda, I.: Cancer Res., 63, 7436 (2003); Khan, J., et a.: Nat. Struct. Mol. Biol., 13, 582 (2006);

Formula: C₂₄H₂₉N₃O₂

Color and Shape: Neat

Molecular weight: 391.51

Ref: TR-F370030

(E)-N-(4-(1-BENZOYLPIPERIDIN-4-YL)BUTYL)-3-(PYRIDIN-3-YL)ACRYLAMIDE

CAS: 658084-64-1

Purity: 95.0%

Molecular weight: 391.5150146484375

Ref: 10-F390257

(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide

CAS: 658084-64-1

(2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide is a drug that inhibits the growth of cancer cells by binding to the ATP binding site of the tyrosine kinase domain. The drug has been shown to inhibit cellular respiration and induce cell death in these cells. In addition, (2E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide has been shown to bind to monoclonal antibodies that are specific for mesenchymal markers, which may make it a potential biomarker for cancer.

Formula: C₂₄H₂₉N₃O₂

Purity: Min. 95%

Molecular weight: 391.51 g/mol

Ref: 3D-FE111880