CAS 66-97-7

Psoralen

Description:

Psoralen is a naturally occurring compound found in various plants, particularly in the seeds of the Psoralea genus. It belongs to the class of furanocoumarins and is characterized by its ability to absorb ultraviolet (UV) light, which allows it to form covalent bonds with DNA. This property makes psoralen useful in phototherapy, particularly for treating skin conditions such as psoriasis and vitiligo, as it enhances the effects of UV light on affected skin. Chemically, psoralen has a molecular formula that includes carbon, hydrogen, and oxygen, and it typically appears as a colorless to pale yellow crystalline solid. It is soluble in organic solvents but has limited solubility in water. Psoralen can also exhibit mutagenic properties due to its interaction with DNA, necessitating careful handling and consideration of its effects in therapeutic applications. Additionally, it has been studied for its potential roles in cancer research and as a photosensitizer in various photochemical reactions.

Formula: C₁₁H₆O₃

InChI: InChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H

InChI key: InChIKey=ZCCUUQDIBDJBTK-UHFFFAOYSA-N

SMILES: O=C1OC2=C(C=C3C(=C2)OC=C3)C=C1

Synonyms:

• 2-Propenoic acid, 3-(6-hydroxy-5-benzofuranyl)-, δ-lactone
• 6,7-Furanocoumarin
• 7H-Furo[3,2-g][1]benzopyran-7-on
• 7H-furo[3,2-g][1]benzopirano-7-ona
• 7H-furo[3,2-g][1]benzopyran-7-one
• 7H-furo[3,2-g][1]benzopyranne-7-one
• 7H-furo[3,2-g]chromen-7-one
• Ficusin
• Furo[2',3':7,6]coumarin
• Furo[2′,3′:7,6]coumarin
• Furo[4',5':6,7]coumarin
• Furo[4′,5′:6,7]coumarin
• Furocoumarin
• Nsc 404562
• Prosuler
• Psoralen 90%
• Psoralene

Psoralen

CAS: 66-97-7

Formula: C₁₁H₆O₃

Purity: >99.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 186.17

Ref: 3B-P2077

Psoralen, 97%

CAS: 66-97-7

Intercalates into DNA; photochemical reagent for the investigation of nucleic acid structure

Formula: C₁₁H₆O₃

Purity: 97%

Molecular weight: 186.16

Ref: 02-J60042

Psoralen

CAS: 66-97-7

Lactones nesoi

Formula: C₁₁H₆O₃

Color and Shape: White Powder

Molecular weight: 186.03169

Ref: 45-1581672

Psoralen

CAS: 66-97-7

Psoralen

Formula: C₁₁H₆NO₃

Purity: 99%

Molecular weight: 186.16

Ref: 54-OR1025503

Psoralen

CAS: 66-97-7

Psoralen

Formula: C₁₁H₆O₃

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 186.16

Ref: 54-BUP00079

Psoralen

CAS: 66-97-7

Formula: C₁₁H₆O₃

Color and Shape: Neat

Molecular weight: 186.16

Ref: 86-MM3915.00

7H-Furo[3,2-g][1]benzopyran-7-one

CAS: 66-97-7

Formula: C₁₁H₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 186.1635

Ref: IN-DA006MZT

Psoralen

CAS: 66-97-7

Psoralen crosslinking between human immunodeficiency virus type 1 RNA and primer tRNA3(Lys).

Formula: C₁₁H₆O₃

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 186.166

Ref: BP-BP1173

Psoralen

CAS: 66-97-7

Psoralen analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₁H₆O₃

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 186.17

Ref: 11-0553S

Psoralen

Controlled Product

CAS: 66-97-7

Applications Psoralens are phytoalexins; they are used by plants in a defensive response to attacks by fungi and insects. They have also shown photosensitizing and phototoxic effects in animals and humans and have been used in photochemotherapy for management of vitiligo, psoriasis, and mycosis fungoides. Used as photochemical probe in biological systems.
References Parsons, B.J., et al.: Photochem. Photobiol., 32, 813 (1980),

Formula: C₁₁H₆O₃

Color and Shape: Neat

Molecular weight: 186.16

Ref: TR-P839800

Psoralen

CAS: 66-97-7

Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.

Formula: C₁₁H₆O₃

Purity: 99.3% - 99.87%

Color and Shape: Crystals From Ether Crystalline Solid

Molecular weight: 186.1635

Ref: TM-T2942

Psoralen

CAS: 66-97-7

Formula: C₁₁H₆O₃

Purity: ≥ 98.0%

Color and Shape: White to light-yellow powder

Molecular weight: 186.16

Ref: 7W-GL6155

Psoralen

CAS: 66-97-7

7H-Furo[3,2-g]chromen-7-one

Formula: C₁₁H₆O₃

Purity: 98+%

Molecular weight: 186.16

Ref: IN-DG34569

Psoralen

CAS: 66-97-7

Lactone

Formula: C₁₁H₆O₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 186.17

Ref: 5G-89770

Psoralen

CAS: 66-97-7

Psoralen is a naturally occurring furocoumarin compound, which is derived from various plants, including those in the Apiaceae family, such as parsley and celery. Its mode of action involves intercalating into DNA and forming covalent cross-links when activated by ultraviolet A (UVA) light. This photoreactivity enables it to modify the biological activity of nucleic acids, making it a valuable tool in both therapeutic and experimental settings.

Formula: C₁₁H₆O₃

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 186.16 g/mol

Ref: 3D-FP15273

Psoralen

CAS: 66-97-7

Formula: C₁₁H₆O₃

Color and Shape: Solid

Molecular weight: 186.16

Ref: BE-BePure-25300

Psoralen

CAS: 66-97-7

Formula: C₁₁H₆O₃

Color and Shape: Solid

Molecular weight: 186.16

Ref: BE-RMT10690

7H-Furo[3,2-g]chromen-7-one

CAS: 66-97-7

Formula: C₁₁H₆O₃

Purity: 98+%

Molecular weight: 186.166

Ref: 10-F235532