CAS 6602-32-0

2-Bromo-3-pyridinol

Description:

2-Bromo-3-pyridinol is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of a bromine atom at the second position and a hydroxyl group (-OH) at the third position of the pyridine ring defines its structure and reactivity. This compound is typically a solid at room temperature and is soluble in polar solvents due to the hydroxyl group, which can engage in hydrogen bonding. 2-Bromo-3-pyridinol is known for its potential applications in medicinal chemistry, particularly as a building block in the synthesis of various pharmaceuticals and agrochemicals. Its reactivity is influenced by the electron-withdrawing nature of the bromine atom, which can enhance nucleophilic substitution reactions. Additionally, the compound may exhibit biological activity, making it of interest in research related to drug development. Safety precautions should be taken when handling this substance, as it may pose health risks if ingested or inhaled.

Formula: C₅H₄BrNO

InChI: InChI=1S/C5H4BrNO/c6-5-4(8)2-1-3-7-5/h1-3,8H

InChI key: InChIKey=YKHQFTANTNMYPP-UHFFFAOYSA-N

SMILES: OC1=C(Br)N=CC=C1

Synonyms:

• 2-Bromo-3-hydroxypyridine
• 2-Bromopyridin-3-Ol
• 3-Pyridinol, 2-bromo-
• Skf 75250
• 2-Bromo-3-pyridinol

2-Bromo-3-hydroxypyridine

CAS: 6602-32-0

Formula: C₅H₄BrNO

Purity: >98.0%(T)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 174.00

Ref: 3B-B1478

2-Bromo-3-hydroxypyridine, 99%

CAS: 6602-32-0

2-Bromo-3-hydroxypyridine is used to produce 2-bromo-4,6-diiodo-3-pyridinol. It is also used in azo dyes and in the synthesis of pterocellin A by reacting with kojic acid and in synthesis of orelline. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product port

Formula: C₅H₄BrNO

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream

Molecular weight: 174.00

Ref: 02-A12687

2-Bromo-3-Hydroxypyridine

CAS: 6602-32-0

Formula: C₅H₄BrNO

Purity: 98%

Color and Shape: Solid

Molecular weight: 173.9954

Ref: IN-DA003352

2-Bromo-3-hydroxypyridine

CAS: 6602-32-0

2-Bromo-3-hydroxypyridine

Formula: C₅H₄BrNO

Purity: 95%

Color and Shape: faint brown powder

Molecular weight: 174.00g/mol

Ref: 54-OR62149

2-Bromo-3-hydroxypyridine

CAS: 6602-32-0

2-Bromo-3-hydroxypyridine

Formula: C₅H₄BrNO

Purity: 98%

Color and Shape: light beige/light brown crystalline solid

Molecular weight: 174.00g/mol

Ref: 54-OR6410

2-Bromo-3-hydroxypyridine (2-Bromo-3-pyridinol)

CAS: 6602-32-0

Formula: C₅H₄BrNO

Molecular weight: 174.00

Ref: 7W-GK6081

2-Bromo-3-hydroxypyridine

CAS: 6602-32-0

Formula: C₅H₄BrNO

Purity: 98%

Color and Shape: Solid, Light brown powder

Molecular weight: 173.997

Ref: 10-F045186

2-Bromo-3-pyridinol

CAS: 6602-32-0

2-Bromo-3-pyridinol is a nicotinic acetylcholine receptor antagonist that has anti-influenza activity. It was synthesized as an analogue of the natural product pyridostigmine, which inhibited influenza in mice. 2-Bromo-3-pyridinol binds to the nicotinic acetylcholine receptor at the same site as nicotine and prevents it from being activated by acetylcholine. This drug also inhibits tumor growth and proliferation in vitro and in vivo, showing potent cytotoxicity against carcinoma cells by inhibiting protein synthesis and cell division. 2-Bromo-3-pyridinol has been shown to inhibit Alzheimer's disease in a mouse model of this disorder. The drug inhibits amyloid plaque formation and toxicity in cultured cells, suggesting its potential for treating this disease.

Formula: C₅H₄BrNO

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Molecular weight: 174 g/mol

Ref: 3D-FB34400