CAS 6631-94-3

2-Acetylphenothiazine

Description:

2-Acetylphenothiazine is an organic compound belonging to the phenothiazine family, characterized by a phenothiazine core with an acetyl group at the second position. This compound typically appears as a solid, often with a yellow to brown color, and is known for its aromatic properties due to the presence of the phenothiazine structure. It is moderately soluble in organic solvents such as ethanol and acetone but has limited solubility in water. 2-Acetylphenothiazine exhibits interesting chemical reactivity, including the ability to undergo oxidation and reduction reactions, making it useful in various synthetic applications. It is also studied for its potential biological activities, including antimicrobial and antitumor properties. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if ingested or inhaled. Overall, 2-acetylphenothiazine is a compound of interest in both synthetic organic chemistry and medicinal chemistry research.

Formula: C₁₄H₁₁NOS

InChI: InChI=1S/C14H11NOS/c1-9(16)10-6-7-14-12(8-10)15-11-4-2-3-5-13(11)17-14/h2-8,15H,1H3

InChI key: InChIKey=JWGBOHJGWOPYCL-UHFFFAOYSA-N

SMILES: C(C)(=O)C=1C=C2C(SC=3C(N2)=CC=CC3)=CC1

Synonyms:

• 1-(10H-Phenothiazin-2-yl)ethan-1-one
• 1-(10H-phenothiazin-2-yl)ethanone
• 2-Acetyl-10H-phenothiazine
• 2-Acetylphenothiazine
• Ethanone, 1-(10H-phenothiazin-2-yl)-
• Ketone, methyl phenothiazin-2-yl
• Labotest-Bb Lt00012652
• Methyl Phenothiazin-2-Yl Ketone
• NSC 169669
• NSC 57951
• 2-Acetyl-phenothiazine

2-Acetylphenothiazine

CAS: 6631-94-3

Formula: C₁₄H₁₁NOS

Purity: >98.0%(GC)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 241.31

Ref: 3B-A2815

1-(10H-Phenothiazin-2-yl)ethanone

CAS: 6631-94-3

Formula: C₁₄H₁₁NOS

Purity: 97%

Molecular weight: 241.31

Ref: 10-F216562

2-Acetyl-10H-phenothiazine

CAS: 6631-94-3

2-Acetyl-10H-phenothiazine

Formula: C₁₄H₁₁NOS

Purity: 98%

Color and Shape: Solid

Molecular weight: 241.30824

Ref: 54-OR10951

ML171

CAS: 6631-94-3

ML171 ,with CAS No. 6631-94-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. ML171 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Formula: C₁₄H₁₁NOS

Color and Shape: Mustard-Colored Powder

Molecular weight: 241.308

Ref: TM-PDK0326

1-(10H-Phenothiazin-2-Yl)Ethanone

CAS: 6631-94-3

Formula: C₁₄H₁₁NOS

Purity: 97%

Color and Shape: Solid

Molecular weight: 241.3082

Ref: IN-DA006NGV

2-Acetyl Phenothiazine

Controlled Product

CAS: 6631-94-3

Applications 2-Acetylphenothiazine is a potent and selective NADPH oxidase 1 (NOX1) inhibitor that blocks NOX1-dependent ROS generation. 2-Acetylphenothiazine has been shown to inhibit SrcYF-induced invadopodia formation in human DLD1 colon cancer cells.
References Gianni, D. et al.: ACS Chem. Biol., 5, 981 (2010); Azuine, M.A. et al.: Pharmacol. Res., 49, 161 (2004);

Formula: C₁₄H₁₁NOS

Color and Shape: Neat

Molecular weight: 241.31

Ref: TR-A187570

ML171

CAS: 6631-94-3

1-(10H-Phenothiazin-2-yl)ethanone

Formula: C₁₄H₁₁NOS

Purity: 98%

Molecular weight: 241.31

Ref: IN-DG15235

Promethazine Impurity 7

CAS: 6631-94-3

Formula: C₁₄H₁₁NOS

Molecular weight: 241.31

Ref: ST-EA-CP-P86023