CAS 66376-36-1
:Alendronic acid
Description:
Alendronic acid, with the CAS number 66376-36-1, is a bisphosphonate compound primarily used in the treatment of osteoporosis and other bone-related disorders. It functions by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density and reducing the risk of fractures. Alendronic acid is characterized by its ability to bind to hydroxyapatite in bone, which enhances its therapeutic efficacy. The compound is typically administered orally and is known for its relatively low bioavailability, necessitating specific dosing instructions, such as taking it on an empty stomach with a full glass of water and remaining upright for a period afterward to minimize gastrointestinal irritation. Alendronic acid is generally well-tolerated, but potential side effects may include gastrointestinal discomfort, musculoskeletal pain, and, in rare cases, osteonecrosis of the jaw. Its chemical structure includes a phosphonate group, which is crucial for its biological activity, and it is classified as a synthetic organic compound.
Formula:C4H13NO7P2
InChI:InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12)
InChI key:InChIKey=OGSPWJRAVKPPFI-UHFFFAOYSA-N
SMILES:C(P(=O)(O)O)(P(=O)(O)O)(CCCN)O
Synonyms:- (4-Amino-1-hydroxy-1-phosphonobutyl) phosphonic acid
- (4-Amino-1-hydroxybutylidene)bisphosphonic acid
- 4-Amino-1-hydroxybutane-1,1-bisphosphonic acid
- 4-Amino-1-hydroxybutane-1,1-diphosphonate
- 4-Amino-1-hydroxybutane-1,1-diphosphonic acid
- 4-Amino-1-hydroxybutane-1,1-diyldiphosphonic acid
- 4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
- A-Hydroxy-D-Aminobutylidenediphosphonic Acid
- Abdp
- Bph 1
- Marvil
- P,P′-(4-Amino-1-hydroxybutylidene)bis[phosphonic acid]
- Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-
- Phosphonic acid, P,P′-(4-amino-1-hydroxybutylidene)bis-
- See more synonyms
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Found 12 products.
Alendronic Acid
CAS:Formula:C4H13NO7P2Purity:>98.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:249.10(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid
CAS:Formula:C4H13NO7P2Purity:98%Color and Shape:SolidMolecular weight:249.0960Alendronic Acid
CAS:Formula:C4H13NO7P2Color and Shape:White To Off-White SolidMolecular weight:249.10Alendronate Sodium Trihydrate
CAS:Formula:C4H12NNaO7P2·3H2OPurity:>97.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:325.13(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid
CAS:Purity:95.0%Color and Shape:Solid, White to slightly pale yellow powderMolecular weight:249.0959930419922Alendronate Acid
CAS:<p>Applications Alendronate acid is an inhibitor of FDPS.<br></p>Formula:C4H13NO7P2Color and Shape:White To BeigeMolecular weight:249.1Alendronic acid
CAS:<p>Alendronic acid is a drug that is used for the treatment of postmenopausal osteoporosis. It belongs to the class of drugs called bisphosphonates and inhibits bone resorption by inhibiting the activity of osteoclasts, which are cells that break down bone tissue. Alendronic acid has been shown to decrease bone loss in women who are treated with this drug. A two-way crossover study was conducted on postmenopausal women to evaluate the efficacy of alendronate sodium (alendronic acid) in reducing the risk of fracture. Results showed that alendronate significantly increased bone mineral density and decreased fracture rates. An analytical method was developed to determine the concentration of alendronate in biological samples using electrochemical impedance spectroscopy.</p>Formula:C4H13NO7P2Purity:Min. 95%Color and Shape:White PowderMolecular weight:249.1 g/molAlendronic Acid
CAS:<p>Alendronic Acid (alendronate) is a nonhormonal medication used for osteoporosis, osteogenesis imperfecta, and several other bone diseases.</p>Formula:C4H13NO7P2Purity:99.89% - ≥95%Color and Shape:White Crystalline PowderMolecular weight:249.1
