CAS 664334-36-5
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Found 5 products.
BKT140
CAS:As described by Peled and coworkers, BKT140 (4F-benzoyl-TN14003) is a biostable, high-affinity chemokine receptor CXCR4 antagonist, which binds CXCR4 with a greater affinity than plerixafor. When combined with G-CSF (granulocyte colony-stimulating factor), BKT140 is a safe and efficient stem cell mobilizer that enabled the collection of a high number of CD34⁺ cells in 1 and 2 aphaeresis procedures, resulting in successful engraftment.Formula:C97H144FN33O19S2Purity:99.1%Color and Shape:White LyophilisateMolecular weight:2159.55Motixafortide
CAS:Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).Formula:C97H144FN33O19S2Purity:98%Color and Shape:SolidMolecular weight:2159.52BKT140
CAS:<p>BKT140 is a potent and selective inhibitor of the CXCR4 receptor. It blocks binding of the chemokine stromal cell-derived factor-1α (SDF-1α) to its receptor, inhibiting cellular proliferation and inducing apoptosis in human cancer cells. BKT140 also inhibits the activity of cyclin-dependent kinases, which are enzymes that regulate the progress of cells through the cell cycle.</p>Formula:C97H144FN33O19S2Purity:Min. 95%Molecular weight:2,159.53 g/molBKT140
CAS:<p>BKT140 is a bacterial strain that has shown efficacy in the treatment of eye disorders such as dry eye syndrome and ocular rosacea. BKT140 was isolated from the blood of a patient with chronic myeloid leukemia, who had an M2 phenotype and high levels of chemokines. The bacterial strain has been shown to inhibit tumor growth by reducing mitochondrial membrane potential and inducing apoptosis in prostate cancer cells. BKT140 also inhibits microenvironment-induced inflammation in bowel disease and autoimmune diseases such as inflammatory bowel disease (IBD) and multiple sclerosis.</p>Formula:C97H144FN33O19S2Purity:Min. 95%Molecular weight:2,159.52 g/mol
