CAS 66611-37-8

3-Pyridinecarboximidamide, N-[2-hydroxy-3-(1-piperidinyl)propoxy]-,dihydrochloride

Description:

3-Pyridinecarboximidamide, N-[2-hydroxy-3-(1-piperidinyl)propoxy]-, dihydrochloride, with CAS number 66611-37-8, is a chemical compound characterized by its complex structure, which includes a pyridine ring, an imidamide functional group, and a piperidine moiety. This compound typically appears as a white to off-white solid and is soluble in water due to the presence of the dihydrochloride salt form, which enhances its solubility and stability. The presence of the hydroxyl group contributes to its potential as a pharmacological agent, possibly influencing its interaction with biological systems. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of therapeutic agents. The compound's properties, such as melting point, boiling point, and specific reactivity, would be influenced by its functional groups and overall molecular configuration. As with many chemical substances, safety data sheets should be consulted for handling and toxicity information, ensuring proper safety protocols are followed in laboratory settings.

Formula: C₁₄H₂₂N₄O₂・2ClH

InChI: InChI=1S/C14H22N4O2.2ClH/c15-14(12-5-4-6-16-9-12)17-20-11-13(19)10-18-7-2-1-3-8-18;;/h4-6,9,13,19H,1-3,7-8,10-11H2,(H2,15,17);2*1H

InChI key: ISGGVCWFTPTHIX-UHFFFAOYSA-N

SMILES: C1CCN(CC1)CC(CO/N=C(/C2=CN=CC=C2)\N)O.Cl.Cl

BGP-15 Hydrochloride

CAS: 459809-32-6, 66611-37-8

Formula: C₁₄H₂₂N₄O₂·xHCl

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Ref: 3B-B6160

BGP-15

CAS: 66611-37-8

BGP-15

Formula: C₁₄H₂₄Cl₂N₄O₂

Purity: 99.5%

Molecular weight: 351.27

Ref: 54-BUP10656

BGP-15

CAS: 66611-37-8

Formula: C₁₄H₂₄Cl₂N₄O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 351.2720

Ref: IN-DA006JN0

BGP-15

CAS: 66611-37-8

N-(2-Hydroxy-3-(piperidin-1-yl)propoxy)nicotinimidamide dihydrochloride

Formula: C₁₄H₂₄Cl₂N₄O₂

Purity: 95%

Molecular weight: 351.27

Ref: IN-DG217132

BGP-15

CAS: 66611-37-8

BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.

Formula: C₁₄H₂₄Cl₂N₄O₂

Purity: 98.17% - 99.99%

Color and Shape: Yellow Solid

Molecular weight: 351.272

Ref: TM-T3649

N-(2-Hydroxy-3-(piperidin-1-yl)propoxy)nicotinimidamide dihydrochloride

CAS: 66611-37-8

Formula: C₁₄H₂₄Cl₂N₄O₂

Purity: 95%

Molecular weight: 351.27

Ref: 10-F235309

BGP 15

Controlled Product

CAS: 66611-37-8

Applications BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.
References (1) Berkovich, L., et al.: Anticancer Drugs. 21, 609 (2010) (2) Szabados, E., et al. Biochem Pharmacol. 59, 937 (2000)

Formula: C₁₄H₂₂N₄O₂·2HCl

Color and Shape: Neat

Molecular weight: 351.27

Ref: TR-B411990

BGP-15

CAS: 66611-37-8

BGP-15 is a mitochondria-targeted pharmacological agent that has been shown to improve cardiac function and reduce oxidative stress. BGP-15 is a peptide with reactive properties, which inhibits the production of reactive oxygen species (ROS) and increases mitochondrial membrane potential. These effects are mediated by activation of the cytochrome c oxidase pathway in the mitochondria, leading to increased energy metabolism and ATP production. BGP-15 has also been shown to reduce cardiomyocyte apoptosis and inhibit myocardial hypertrophy in vivo. The therapeutic potential of BGP-15 has been demonstrated in various models, including murine hepatoma cells, where it promotes caspase-independent cell death (apoptosis). This drug may have beneficial effects against infectious diseases such as tuberculosis or malaria, as well as autoimmune diseases such as rheumatoid arthritis.

Formula: C₁₄H₂₄Cl₂N₄O₂

Purity: Min. 95%

Molecular weight: 351.27 g/mol

Ref: 3D-RCA61137