CAS 66644-81-3

Veralipride

Description:

Veralipride is a chemical compound classified as a benzamide derivative, primarily recognized for its use as an atypical antipsychotic and antidepressant. It acts as a selective dopamine D2 receptor antagonist, which contributes to its therapeutic effects in treating various psychiatric disorders. The compound is characterized by its ability to modulate neurotransmitter activity, particularly in the dopaminergic pathways, which can help alleviate symptoms of anxiety and depression. Veralipride is typically administered in oral form and has been studied for its efficacy in managing conditions such as premenstrual syndrome and other mood disorders. Its pharmacological profile includes a relatively favorable side effect profile compared to traditional antipsychotics, although it may still present risks such as extrapyramidal symptoms in some patients. As with any medication, the use of Veralipride should be closely monitored by healthcare professionals to ensure safety and effectiveness.

Formula: C₁₇H₂₅N₃O₅S

InChI: InChI=1/C17H25N3O5S/c1-4-7-20-8-5-6-12(20)11-19-17(21)14-9-13(26(18,22)23)10-15(24-2)16(14)25-3/h4,9-10,12H,1,5-8,11H2,2-3H3,(H,19,21)(H2,18,22,23)

InChI key: InChIKey=RYJXBGGBZJGVQF-UHFFFAOYSA-N

SMILES: C(NCC1N(CC=C)CCC1)(=O)C2=C(OC)C(OC)=CC(S(N)(=O)=O)=C2

Synonyms:

• 2,3-dimethoxy-N-{[1-(prop-2-en-1-yl)pyrrolidin-2-yl]methyl}-5-sulfamoylbenzamide
• 266-435-5
• 5-(Aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]benzamide
• Agreal
• Benzamide, 5-(aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-
• Lir 1660
• N-(1-Allyl-2-pyrrolidinyl)methyl-2,3-dimethoxy-5-sulfamoylbenzamide
• N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-veratramide
• N-[(1-Allylpyrrolidin-2-yl)methyl]-2,3-dimethoxy-5-sulfamoylbenzamide
• N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(aminosulfonyl)-2,3-dimethoxybenzamide
• benzamide, 5-(aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]-
• Veralipride
• N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-sulphamoyl-2-veratramide
• Velaripride

Benzamide,5-(aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-

CAS: 66644-81-3

Formula: C₁₇H₂₅N₃O₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 383.4625

Ref: IN-DA01CCPN

Veralipride

CAS: 66644-81-3

Veralipride

Purity: ≥98%

Molecular weight: 383.46g/mol

Ref: 54-BUP12228

Veralipride

CAS: 66644-81-3

Formula: C₁₇H₂₅N₃O₅S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 383.46

Ref: 3B-V0163

Veralipride

CAS: 66644-81-3

Veralipride ((±)-Veralipride) is an antagonist of D2 receptor.

Formula: C₁₇H₂₅N₃O₅S

Purity: 99.65%

Color and Shape: Solid

Molecular weight: 383.46

Ref: TM-T7632

Veralipride

Controlled Product

CAS: 66644-81-3

Dopamine (D2) receptor antagonist

Formula: C₁₇H₂₅N₃O₅S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 383.46 g/mol

Ref: 3D-BV162329

VERALIPRIDE

CAS: 66644-81-3

Purity: 95%

Molecular weight: 383.4599915

Ref: 10-F844541

Veralipride

Controlled Product

CAS: 66644-81-3

Applications Veralipride, a synthetic benzamide derivative with antidopaminergic action, is effective in reducing the frequency and severity of hot flashes associated with menopausal hypoestrogenism, gaining interest as a non-hormonal treatment for climacteric flushing.
References Casper, R., et al.: Clin. Endocrinol., 22, 293 (1985), Melis, G., et al.: J. Clin. Endocrinol. Metab., 66, 964 (1988), Stearns, V., et al.: Lancet, 360, 1851 (2002),

Formula: C₁₇H₂₅N₃O₅S

Color and Shape: Neat

Molecular weight: 383.46

Ref: TR-V122500