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CAS 67035-22-7

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Dehydronifedipine

Description:
Dehydronifedipine is a chemical compound that belongs to the class of dihydropyridine calcium channel blockers, primarily used in the treatment of hypertension and angina. It is a derivative of nifedipine, characterized by the absence of a hydrogen atom at a specific position in its molecular structure, which influences its pharmacological properties. The compound typically exhibits a lipophilic nature, allowing for good membrane permeability, which is essential for its action on vascular smooth muscle cells. Dehydronifedipine functions by inhibiting calcium influx through voltage-gated calcium channels, leading to vasodilation and a subsequent decrease in blood pressure. Its pharmacokinetics may include a relatively rapid onset of action, with a duration that can vary based on formulation. Additionally, like other dihydropyridines, it may have side effects such as peripheral edema, flushing, and palpitations. As with any medication, its use should be guided by a healthcare professional, considering potential interactions and contraindications.
Formula:C17H16N2O6
InChI:InChI=1S/C17H16N2O6/c1-9-13(16(20)24-3)15(14(10(2)18-9)17(21)25-4)11-7-5-6-8-12(11)19(22)23/h5-8H,1-4H3
InChI key:InChIKey=UMQHJQGNGLQJPF-UHFFFAOYSA-N
SMILES:C(OC)(=O)C=1C(=C(C(OC)=O)C(C)=NC1C)C2=C(N(=O)=O)C=CC=C2
Synonyms:
  • 3,5-Pyridinedicarboxylic Acid, 2,6-Dimethyl-4-(2-Nitrophenyl)-, Dimethyl Ester
  • 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-, 3,5-dimethyl ester
  • B 4759
  • BAY-b 4759
  • Dehydronifedipine
  • Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylate
  • Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate
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Found 18 products.