CAS 67483-13-0

disodium 2,2'-(E)-ethene-1,2-diylbis(5-isothiocyanatobenzenesulfonate)

Description:

Disodium 2,2'-(E)-ethene-1,2-diylbis(5-isothiocyanatobenzenesulfonate), commonly referred to by its CAS number 67483-13-0, is a synthetic chemical compound characterized by its unique structure that includes two sulfonate groups and isothiocyanate functionalities. This compound is typically used in biochemical applications, particularly in the field of molecular biology and biochemistry, as a labeling agent or in the synthesis of various derivatives. Its isothiocyanate groups are reactive, allowing for conjugation with biomolecules, which is useful in the development of assays and probes. The presence of sulfonate groups enhances its solubility in aqueous solutions, making it suitable for biological applications. Additionally, the compound's stability and reactivity can be influenced by environmental factors such as pH and temperature. Overall, this compound serves as a valuable tool in research and diagnostic applications, particularly in the study of proteins and nucleic acids.

Formula: C₁₆H₈N₂Na₂O₆S₄

InChI: InChI=1/C16H10N2O6S4.2Na/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24;;/h1-8H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2/b2-1+;;

SMILES: C(=Cc1ccc(cc1S(=O)(=O)O)N=C=S)c1ccc(cc1S(=O)(=O)O)N=C=S.[Na].[Na]

Disodium 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonate

CAS: 207233-90-7, 67483-13-0

Formula: C₁₆H₈N₂Na₂O₆S₄

Purity: >90.0%(HPLC)(N)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 498.47

Ref: 3B-D2475

4,4′-Diisothiocyanato-2.2′-stilbenedisulfonic acid disodium salt

CAS: 67483-13-0

Formula: C₁₆H₈N₂Na₂O₆S₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 498.4841

Ref: IN-DA003PEM

DIDS sodium salt

CAS: 67483-13-0

DIDS sodium salt

Purity: ≥95%

Molecular weight: 498.5g/mol

Ref: 54-BUP11482

Disodium 4,4'-DIIsothiocyanato -2,2'-Stilbenedisulfonate Hydrate

CAS: 67483-13-0

Disodium 4,4'-DIIsothiocyanato -2,2'-Stilbenedisulfonate Hydrate

Purity: 90%

Molecular weight: 498.47g/mol

Ref: 54-OR1025283

DIDS sodium salt

CAS: 67483-13-0

DIDS sodium salt (MDL101114ZA) is a dual inhibitor of ABCA1 and VDAC1.

Formula: C₁₆H₈N₂Na₂O₆S₄

Purity: 95.74% - 99.34%

Color and Shape: Yellow Powder

Molecular weight: 498.5

Ref: TM-T18975

4,4'-Diisothiocyano-2,2'-stilbenedisulfonic Acid, Disodium Salt

Controlled Product

CAS: 67483-13-0

Stability Recommend Desiccate and Storage at -20°C
Applications Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle.Fluorescence: max. Abs. l = 341, max. Em. l = 415 (in water)
References Horie, S., et al.: Res. Comm. Chem. Pathol. Pharmacol., 79, 117 (1993) Mayinger, P. & Meyer, D.I.: EMBO J., 12, 659 (1993); Am. J. Physiol. 262, C803 (1992); J. Biol. Chem. 266, 13355 (1991).

Formula: C₁₆H₈N₂O₆S₄·2Na

Color and Shape: Neat

Molecular weight: 498.48

Ref: TR-D460600

4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt

CAS: 67483-13-0

Formula: C₁₆H₈N₂Na₂O₆S₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 498.47

Ref: 10-F050210