CAS 67763-87-5

Bleomycin, hydrochloride

Description:

Bleomycin hydrochloride is a glycopeptide antibiotic derived from the bacterium Streptomyces verticillus. It is primarily used as an antineoplastic agent in cancer treatment, particularly for germ cell tumors, squamous cell carcinomas, and lymphomas. The compound exhibits a unique mechanism of action by inducing DNA strand breaks through the formation of free radicals, which ultimately leads to cell death. Bleomycin is characterized by its ability to bind to DNA and its relatively low myelosuppressive effects compared to other chemotherapeutic agents, making it a valuable option in combination therapies. The hydrochloride form enhances its solubility in water, facilitating its administration via injection. However, its use is associated with potential side effects, including pulmonary toxicity, skin reactions, and fever. Due to these risks, careful monitoring is essential during treatment. Overall, Bleomycin hydrochloride remains an important tool in oncology, particularly for specific types of tumors where its unique properties can be effectively utilized.

Formula: Unspecified

InChI: InChI=1S/C55H83N17O21S3.ClH/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);1H/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-;/m0./s1

InChI key: BODDZCXQPQPRES-OYALTWQYSA-O

SMILES: CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.Cl

Synonyms:

• Bleomycin chlorhydrate
• Bleomycin hydrochloride [Bleomycins]
• Unii-7Z9O46Ja4A
• Bleomycin, hydrochloride

Bleomycin hydrochloride

CAS: 67763-87-5

Formula: C₆₄H₁₁₃ClN₂₀O₂₁S₃

Purity: 98%

Molecular weight: 1630.3514

Ref: IN-DA00FB6L

Bleomycin hydrochloride

CAS: 67763-87-5

Bleomycin hydrochloride is a glycopeptide antibiotic and a DNA synthesis inhibitor. Bleomycin Sulfate has anti-tumor activity. High-Quality, Low-Cost!

Formula: C₅₅H₈₄ClN₁₇O₂₁S₃

Purity: 98% - 99.95%

Color and Shape: White Solid

Molecular weight: 1451.005

Ref: TM-T6116L

Bleomycin HCl

CAS: 67763-87-5

Inducer of DNA strand breaks; glycopeptide antibiotic, anti-neoplastic

Formula: C₅₀H₇₁N₁₆O₂₁S₂R•(HCl)x

Purity: Min. 95%

Color and Shape: White To Off-White Solid

Ref: 3D-AB16398