CAS 67776-06-1

S-Nitroso-N-acetyl-DL-penicillamine

Description:

S-Nitroso-N-acetyl-DL-penicillamine is a chemical compound that belongs to the class of S-nitrosothiols, which are known for their role in biological signaling and potential therapeutic applications. This compound is characterized by the presence of a nitroso group (–NO) attached to the sulfur atom of penicillamine, an amino acid derivative. It exhibits properties such as being a nitric oxide donor, which can influence various physiological processes, including vasodilation and modulation of cellular signaling pathways. The compound is typically soluble in water and organic solvents, making it versatile for various experimental conditions. Its stability can be affected by factors such as light and temperature, which are important considerations for storage and handling. S-Nitroso-N-acetyl-DL-penicillamine has been studied for its potential applications in cardiovascular health and as a therapeutic agent in conditions where nitric oxide signaling is disrupted. However, further research is necessary to fully understand its mechanisms of action and therapeutic potential.

Formula: C₇H₁₂N₂O₄S

InChI: InChI=1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)

InChI key: InChIKey=ZIIQCSMRQKCOCT-UHFFFAOYSA-N

SMILES: C(C(SN=O)(C)C)(NC(C)=O)C(O)=O

Synonyms:

• N-Acetyl-S-nitroso-DL-penicillamine
• S-Nitroso-N-acetyl-DL-penicillamine
• Valine, N-acetyl-3-(nitrosothio)-
• DL-Valine, N-acetyl-3-(nitrosothio)-
• N-Acetyl-3-(nitrosothio)valine

S-Nitroso-N-acetyl-DL-penicillamine

CAS: 67776-06-1

S-Nitroso-N-acetyl-DL-penicillamine (SNAP) acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and .

Formula: C₇H₁₂N₂O₄S

Purity: 97.42% - >99.99%

Color and Shape: Green Crystalline Solid

Molecular weight: 220.25

Ref: TM-T12808

Valine,N-acetyl-3-(nitrosothio)-

CAS: 67776-06-1

Formula: C₇H₁₂N₂O₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 220.2462

Ref: IN-DA0063E3

S-Nitroso-N-Acetyl-D,L-Penicillamine

CAS: 67776-06-1

S-Nitroso-N-Acetyl-D,L-Penicillamine

Purity: 97%

Molecular weight: 220.25g/mol

Ref: 54-OR1014922

S-Nitroso-N-acetyl-DL-penicillamine

CAS: 67776-06-1

S-Nitroso-N-acetyl-DL-penicillamine

Purity: ≥95%

Molecular weight: 220.25g/mol

Ref: 54-BUP11351

S-Nitroso-N-acetyl-DL-penicillamine

CAS: 67776-06-1

Formula: C₇H₁₂N₂O₄S

Molecular weight: 220.25

Ref: 7W-GL8931

2-acetamido-3-methyl-3-(nitrososulfanyl)butanoic acid

CAS: 67776-06-1

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 220.24000549316406

Ref: 10-F516837

S-Nitroso-N-acetyl-D,L-penicillamine

Controlled Product

CAS: 67776-06-1

Applications Produced concentration-related relaxations of mouse anococcygeus, in a range similar to that already found for NO and other nitrovasodilators. A potent relaxant of non-vascular smooth muscle. Serves as an NO donor.
References Bauer & Fung: J. Pharmacol. Exp. Ther., 256, 249 (1991), Gibson, A., et al.: Brit. J. Pharm., 107, 715 (1992), Shaffer, et al.: J. Pharm. Exper. Ther., 260, 286 (1992), Jansen, A., et al.: J. Pharmacol. Exp. Ther., 261, 154 (1992), Lander, H.M. et al.: J. Immunol., 150, 1509 (1993)

Formula: C₇H₁₂N₂O₄S

Color and Shape: Green Solid

Molecular weight: 220.25

Ref: TR-N522500

SNAP

CAS: 67776-06-1

SNAP is a cyclase inhibitor that binds to the DNA-dependent RNA polymerase, preventing transcription and replication. It has been shown to have potent antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus, Streptococcus pneumoniae, and Enterococcus faecalis. SNAP also has antioxidant properties in vitro, which may be due to its ability to increase mitochondrial membrane potential and inhibit the production of reactive oxygen species. In addition, SNAP has been shown to have a protective effect on neuronal cells in culture by inhibiting the death of neurons induced by glutamate or oxidant stress. However, SNAP is not active against Gram-negative bacteria or fungi. The effects of SNAP were studied in a pharmacological treatment study on rats with cerebral malaria. Results showed that SNAP was able to significantly reduce mortality rates and neurological deficits caused by cerebral malaria when administered at physiological levels (1mg/kg). Additionally, this drug was found to have low potency as an

Formula: C₇H₁₂N₂O₄S

Purity: Min. 95%

Molecular weight: 220.25 g/mol

Ref: 3D-FS46817

S-Nitroso-N-acetyl-D,L-penicillamine

CAS: 67776-06-1

Formula: C₇H₁₂N₂O₄S

Molecular weight: 220.24

Ref: ST-EA-CP-P45004