CAS 68-22-4

Norethindrone

Description:

Norethindrone is a synthetic progestin, primarily used in hormonal contraceptives and hormone replacement therapy. It is characterized by its ability to mimic the natural hormone progesterone, thereby regulating various reproductive functions. Norethindrone is typically presented as a white to off-white crystalline powder, with a molecular formula of C20H26O2 and a molecular weight of approximately 298.43 g/mol. It is relatively stable under normal conditions but should be stored in a cool, dry place away from light to maintain its efficacy. The substance is lipophilic, allowing it to be absorbed well in the body, and it has a moderate solubility in organic solvents. Norethindrone acts by inhibiting ovulation, altering the menstrual cycle, and thickening cervical mucus to prevent sperm penetration. Its pharmacological effects can lead to various side effects, including changes in menstrual patterns, weight gain, and mood alterations. Due to its hormonal activity, it is contraindicated in certain conditions, such as hormone-sensitive cancers and severe liver disease.

Formula: C₂₀H₂₆O₂

InChI: InChI=1/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16?,17?,18?,19-,20-/m0/s1

InChI key: InChIKey=VIKNJXKGJWUCNN-XGXHKTLJSA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)([C@@]4(C(CC3)=CC(=O)CC4)[H])[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• (17Beta)-17-Ethynyl-17-Hydroxyestr-4-En-3-One
• (17α)-17-Hydroxy-19-Norpregn-4-en-20-yn-3-one
• (8Xi,9Xi,14Xi,17Beta)-17-Ethynyl-17-Hydroxyestr-4-En-3-One
• 17-Alpha-Ethynyl-17-Beta-Hydroxyoestr-4-En-3-One
• 17-Ethynyl-17-Hydroxyestr-4-En-3-One
• 17-Hydroxy-19-nor-17α-pregn-4-en-20 yn-3-one
• 17α-Ethinyl-17β-hydroxy-Δ4-estren-3-one
• 17α-Ethinyl-17β-hydroxy-Δ⁴-estren-3-one
• 17α-Ethinyl-19-nortestosterone
• 17α-Ethinylestr-4-en-17β-ol-3-one
• 17α-Ethynyl-17-hydroxy-4-estrene-3-one
• 17α-Ethynyl-17-hydroxyest-4-en-3-one
• 17α-Ethynyl-17-hydroxyestr-4-en-3-one
• 17α-Ethynyl-17β-hydroxy-19-norandrost-4-en-3-one
• 17α-Ethynyl-17β-hydroxyestr-4-en-3-one
• 17α-Ethynyl-19-nor-androst-4-en-17β-ol-3-one
• 17α-Ethynyl-19-nortestosterone
• 17α-Ethynyl-3-oxo-4-estren-17β-ol
• 17β-Hydroxy-17α-ethynylestr-4-en-3-one
• 19-Nor-17α-ethynyl-17β-hydroxy-4-androsten-3-one
• 19-Nor-17α-ethynyl-4-androsten-17β-ol-3-one
• 19-Nor-17α-ethynylandrosten-17β-ol-3-one
• 19-Nor-17α-ethynyltestosterone
• 19-Nor-17α-pregn-4-en-20-yn-3-one, 17-hydroxy-
• 19-Norandrost-4-en-3-one, 17α-ethynyl-17β-hydroxy-
• 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17α)-
• 19-Nortestosterone, 17-ethynyl-
• Anovule
• Conludaf
• Conludag
• Estr-4-ene-17α-ethynyl-17β-ol-3-one
• Ethinylnortestosterone
• Ethynylnortestosterone
• Gestest
• Menzol
• Micronett
• Micronor
• Micronovum
• Mini-Pe
• Mini-pill
• Nor-QD
• Noralutin
• Norcolut
• Norethisteron
• Norethisterone
• Norethisterone,98%
• Norethynodrone
• Noretisterona
• Noretisterone Dak
• Norfor
• Norgestin
• Norluten
• Norlutin
• Norluton
• Normapause
• Norpregneninolone
• Nsc 9564
• Primolut N
• Proluteasi
• Sc 4640
• Triella
• Utovlan
• NORETHINDRONE
• 19-NOR-17ALPHA-ETHYNYLTESTOSTERONE
• 19-NOR-4-ETHISTERONE
• 19-NOR-17ALPHA-ETHYNYL-4-ANDROSTEN-17BETA-OL-3-ONE
• 17-HYDROXY-19-NOR-17ALPHA-4-PREGNEN-20-YN-3-ONE
• 17ALPHA-ETHYNYL-17BETA-HYDROXY-19-NOR-4-ANDROSTEN-3-ONE
• 19-NOR-4-ANDROSTEN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE
• 19-NORETHINDRONE
• 19-NORETHISTERONE
• 4-ESTREN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE
• 17ALPHA-ETHYNYL-19-NORTESTOSTERONE
• (17-alpha)-17-Hydroxy-19-norpregn-4-en-20-yn-3-one
• (17alpha)-19-norpregn-4-en-20-yn-3-on
• 17-alpha-ethinyl-17-beta-hydroxy-delta(sup:4)-estren-3-one
• 17-alpha-19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-

Norethisterone

CAS: 68-22-4

Formula: C₂₀H₂₆O₂

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 298.43

Ref: 3B-N0449

NORETHISTERONE RS

CAS: 68-22-4

NORETHISTERONE RS

Formula: C₂₀H₂₆O₂

Molecular weight: 298.4192

Ref: 41-ICRS0366

NORETHISTERONE CRS

CAS: 68-22-4

NORETHISTERONE CRS

Formula: C₂₀H₂₆O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 298.4192

Ref: 41-N1200000

Norethisterone

CAS: 68-22-4

Norethisterone

Formula: C₂₀H₂₆O₂

Purity: 98.4%

Color and Shape: White To Off-White

Molecular weight: 298.19328

Ref: 47-266

NORETHISTERONE FOR SYSTEM SUITABILITY CRS

CAS: 68-22-4

NORETHISTERONE FOR SYSTEM SUITABILITY CRS

Formula: C₂₀H₂₆O₂

Molecular weight: 298.4192

Ref: 41-Y0000522

Norethindrone

CAS: 68-22-4

Estrogens and progestins

Formula: C₂₀H₂₆O₂

Color and Shape: White Powder

Molecular weight: 298.43 g/mol

Ref: 45-1469005

Norethindrone

CAS: 68-22-4

Norethindrone is a potent synthetic hormone used for amenorrhea, uterine bleeding, endometriosis, and contraception.

Formula: C₂₀H₂₆O₂

Purity: 99.33% - 99.82%

Color and Shape: White Crystalline Powder Solid

Molecular weight: 298.42

Ref: TM-T1514

Norethindrone-d6

CAS: 68-22-4

Formula: C₂₀H₂₀D₆O₂

Color and Shape: Off-White Solid

Molecular weight: 304.46

Ref: 4Z-N-293

Norethindrone

CAS: 68-22-4

Norethindrone

Purity: 98%

Molecular weight: 298.42g/mol

Ref: 54-OR1029303

Norethindrone

CAS: 68-22-4

Formula: C₂₀H₂₆O₂

Purity: ≥ 97.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 298.42

Ref: 7W-GP2176

Norethindrone

CAS: 68-22-4

Norethindrone

Purity: ≥98%

Molecular weight: 298.42g/mol

Ref: 54-BUP14913

Norethindrone (Norethisterone Acetate EP Impurity A, Levonorgestrel EP Impurity U)

CAS: 68-22-4

Formula: C₂₀H₂₆O₂

Color and Shape: White To Off-White Solid

Molecular weight: 298.43

Ref: 4Z-N-294

Norethisterone 100 µg/mL in Acetonitrile

CAS: 68-22-4

Formula: C₂₀H₂₆O₂

Color and Shape: Single Solution

Molecular weight: 298.42

Ref: 04-A15644950AL-100

Norethisterone

Controlled Product

CAS: 68-22-4

Formula: C₂₀H₂₆O₂

Color and Shape: Neat

Molecular weight: 298.42

Ref: 86-MM0218.00

Norethisterone

Controlled Product

CAS: 68-22-4

Formula: C₂₀H₂₆O₂

Color and Shape: Neat

Molecular weight: 298.42

Ref: 04-C15644950

Norethindrone Acetate Dimer

CAS: 68-22-4

Formula: C₄₂H₅₄O₆

Color and Shape: White To Off-White Solid

Molecular weight: 654.89

Ref: 4Z-N-2941

Norethindrone

Controlled Product

CAS: 68-22-4

Applications Norethindrone is a progesterone in combination with acetate used as an oral contraceptive (1,2). It is reasonably anticipated to be a human carcinogen. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. This compound is a contaminant of emerging concern (CECs).
References 1. Shroff, A. et al.: Anal. Profiles Drug Subst. 1975 ; 4;268-2932. Singh, H. et al.: Am. J .Obstet. Gynecol. 1979 Oct 1;135(3):409-14

Formula: C₂₀H₂₆O₂

Color and Shape: White To Off-White

Molecular weight: 298.42

Ref: TR-N676000

Norethindrone-d7 (Major)

Controlled Product

CAS: 68-22-4

Formula: C₂₀H₁₉D₇O₂

Color and Shape: Neat

Molecular weight: 305.46

Ref: TR-N676004

Norethindrone

Controlled Product

CAS: 68-22-4

Norethindrone is a synthetic progestin that is used in oral contraceptives. Norethindrone has been shown to significantly up-regulate the expression of polymerase chain reaction (PCR) products from a response element in human endometrial cells, suggesting that it may be involved in disease activity. In addition, norethindrone has been shown to inhibit the growth of various infectious microorganisms, including those responsible for diseases such as endometriosis and pelvic inflammatory disease. The drug has also been shown to have receptor activity on cells that are responsive to progesterone and testosterone.

Formula: C₂₀H₂₆O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 298.42 g/mol

Ref: 3D-FN26442

Levonorgestrel EP Impurity U

CAS: 68-22-4

Formula: C₂₀H₂₆O₂

Molecular weight: 298.43

Ref: ST-EA-CP-L19021