CAS 68401-81-0

Ceftizoxime

Description:

Ceftizoxime is a broad-spectrum cephalosporin antibiotic that is primarily used to treat bacterial infections. It is characterized by its ability to inhibit bacterial cell wall synthesis, which is crucial for the growth and reproduction of bacteria. Ceftizoxime is effective against a variety of Gram-positive and Gram-negative bacteria, making it a valuable option in clinical settings. The compound is typically administered via injection and is known for its stability against certain beta-lactamases, enzymes produced by some bacteria that can confer resistance to antibiotics. Its pharmacokinetic properties include good tissue penetration and a relatively short half-life, necessitating multiple doses for effective treatment. Ceftizoxime is generally well-tolerated, but like all antibiotics, it may cause side effects, including allergic reactions or gastrointestinal disturbances. It is important to use this antibiotic judiciously to minimize the risk of developing antibiotic resistance. As with any medication, its use should be guided by susceptibility testing and clinical judgment.

Formula: C₁₃H₁₃N₅O₅S₂

InChI: InChI=1S/C13H13N5O5S2/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22)/b17-7-/t8-,11-/m1/s1

InChI key: InChIKey=NNULBSISHYWZJU-LLKWHZGFSA-N

SMILES: O=C1N2[C@@]([C@@H]1NC(/C(=N\OC)/C3=CSC(N)=N3)=O)(SCC=C2C(O)=O)[H]

Synonyms:

• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-8-oxo-, (6R,7R)-
• 7-[[(2Z)-2-(2-azaniumylidene-3H-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• Ceftisomin
• Ceftizoxime acid
• Epocelin
• Ceftizoxime

Ceftizoxime

CAS: 68401-81-0

Formula: C₁₃H₁₃N₅O₅S₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 383.40

Ref: 3B-C2622

Ceftizoxime

CAS: 68401-81-0

Antibiotics nesoi

Formula: C₁₃H₁₃N₅O₅S₂

Color and Shape: White Pale Yellow Crystalline Powder

Molecular weight: 383.03581

Ref: 45-1098173

Ceftizoxime

CAS: 68401-81-0

Ceftizoxime

Formula: C₁₃H₁₃N₅O₅S₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 383.4

Ref: 54-OR1030134

Ceftizoxime

CAS: 68401-81-0

Formula: C₁₃H₁₃N₅O₅S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 383.4028

Ref: IN-DA003OQG

Ceftizoxime

CAS: 68401-81-0

Formula: C₁₃H₁₃N₅O₅S₂

Molecular weight: 383.41

Ref: 4Z-C-901

Ceftizoxime

CAS: 68401-81-0

Ceftizoxime

Formula: C₁₃H₁₃N₅O₅S₂

Purity: ≥98%

Molecular weight: 383.4

Ref: 54-BUP11726

Ceftizoxime

CAS: 68401-81-0

Formula: C₁₃H₁₃N₅O₅S₂

Purity: ≤ 1.0%

Color and Shape: White to off-white powder or light-yellow powder

Molecular weight: 383.40

Ref: 7W-GA1367

Ceftizoxime (Standard)

CAS: 68401-81-0

Ceftizoxime (Standard) is a reference standard for research and analysis in studies involving Ceftizoxime. Ceftizoxime (Epocelin) is a cephalosporin-based, potent antibacterial agent which can be administered intravenously or by suppository. It is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms.

Formula: C₁₃H₁₃N₅O₅S₂

Color and Shape: Solid

Molecular weight: 383.40

Ref: TM-TMSM-3599

Ceftizoxime

CAS: 68401-81-0

Ceftizoxime (Epocelin), a broad-spectrum cephalosporin antibiotic, resists beta-lactamases, effective IV/suppository.

Formula: C₁₃H₁₃N₅O₅S₂

Purity: 99.72% - 99.91%

Color and Shape: White Solid

Molecular weight: 383.40

Ref: TM-T4501

Ceftizoxime

Controlled Product

CAS: 68401-81-0

Stability Hygroscopic
Applications Ceftizoxime is a cephalosporin based, potent antibacterial agent.
References Zhang, J. et al.: Chem. Res. Toxicol., 26, 1168 (2013); Ekinci, D. et al.: J. Enz. Inhib. Med. Chem., 28, 824 (2013);

Formula: C₁₃H₁₃N₅O₅S₂

Color and Shape: Neat

Molecular weight: 383.4

Ref: TR-C244760

CEFTIZOXIME

CAS: 68401-81-0

Purity: 97%

Molecular weight: 383.3999939

Ref: 10-F819026

Ceftizoxime-d3

Controlled Product

CAS: 68401-81-0

Formula: C₁₃D₃H₁₀N₅O₅S₂

Color and Shape: Neat

Molecular weight: 386.421

Ref: TR-C244762

Ceftizoxime

CAS: 68401-81-0

Ceftizoxime is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating respiratory tract infections, urinary tract infections, and gonorrhea.

Formula: C₁₃H₁₃N₅O₅S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 383.41 g/mol

Ref: 3D-FC40907