CAS 6846-03-3

Bradykinin, acetate salt

Description:

Bradykinin, acetate salt, is a peptide that functions as a potent vasodilator and plays a significant role in various physiological processes, including inflammation and pain signaling. It is composed of a sequence of amino acids and is classified as a nonapeptide, specifically derived from the kinin family. The acetate salt form indicates that the bradykinin molecule is associated with acetic acid, which can enhance its solubility and stability in solution. This compound is known for its ability to induce smooth muscle contraction and increase vascular permeability, contributing to its role in the inflammatory response. Bradykinin acts through specific receptors, primarily the B2 receptor, leading to various biological effects such as hypotension and increased blood flow. Its therapeutic potential is being explored in various medical conditions, including cardiovascular diseases and pain management. However, due to its rapid degradation in the body, its clinical applications often require careful formulation and delivery methods to ensure efficacy.

Formula: C₅₀H₇₃N₁₅O₁₁.xC₂H₄O₂

InChI: InChI=1S/C50H73N15O11.C2H4O2/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55;1-2(3)4/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57);1H3,(H,3,4)/t32-,33-,34-,35-,36-,37-,38-,39-;/m0./s1

InChI key: VIGBULRGBBKXHS-MIEKKPBHSA-N

SMILES: CC(=O)O.C1C[C@H](N(C1)C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCN=C(N)N)N)C(=O)NCC(=O)N[C@@H](CC3=CC=CC=C3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@@H](CC5=CC=CC=C5)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

Bradykinin Acetate Salt

CAS: 6846-03-3

For cellular and molecular biology applications

Color and Shape: White to off-white, Powder

Ref: 02-J60345

Bradykinin

CAS: 6846-03-3

The pharmacological properties of bradykinin include smooth muscle contraction, vasodilation and hypotension. Bradykinin increases capillary permeability together with edema formation and induction of pain. Bradykinin induces bronchoconstriction in asthmatic subjects and symptoms of rhinitis in nasal provocation. CAS Number (net): 58-82-2.

Formula: C₅₀H₇₃N₁₅O₁₁

Purity: 98.9%

Color and Shape: White

Molecular weight: 1060.22

Ref: 01-4002961

Bradykinin (acetate)

CAS: 6846-03-3

Bradykinin (acetate)

Formula: C₅₂H₇₇N₁₅O₁₃

Purity: 99.5%

Molecular weight: 1120.26

Ref: 54-BUP00627

Bradykinin acetate salt

CAS: 6846-03-3

Bradykinin acetate salt

Formula: C₅₀H₇₃N₁₅O₁₁·CH₃CO₂H

Color and Shape: White Solid-Powder

Molecular weight: 1120.26048

Ref: 54-BIB8001

Bradykinin xacetate salt

CAS: 6846-03-3

Formula: C₅₂H₇₇N₁₅O₁₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 1120.2605

Ref: IN-DA00FEL8

Bradykinin (acetate)

CAS: 6846-03-3

Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system.

Formula: C₅₂H₇₇N₁₅O₁₃

Purity: 99.68% - >99.99%

Color and Shape: White Viscous

Molecular weight: 1120.26

Ref: TM-T21610

Bradykinin Acetate

Controlled Product

CAS: 6846-03-3

Applications Bradykinin Acetate elicits vasoconstriction, a systemic blood pressure reflex, a stimulation of respiration, and contraction of the nictitating membrane.
References Wiegershausen, B., Klausch, B.: Experientia, 23, 29 (1967)

Formula: C₅₀H₇₃N₁₅O₁₁·C₂H₄O₂

Color and Shape: Neat

Molecular weight: 1120.26

Ref: TR-B676680

Bradykinin acetate

Controlled Product

CAS: 6846-03-3

Bradykinin acetate is a synthetic form of Bradykinin that is used as a nutritional supplement for people with chronic bronchitis. It is a solid-phase synthesis of bradykinin and has been shown to have the same effects on blood pressure as bradykinin b2. Bradykinin acetate has also been shown to cause vasodilation, which may be due to its ability to bind to the ryanodine receptor and activate calcium release from intracellular stores. This drug can be detected in test samples using laser ablation waveform analysis.

Formula: C₅₀H₇₃N₁₅O₁₁·xC₂H₄O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1120.26

Ref: 3D-FA49254