CAS 68617-64-1

3-(2-Pyridyldithio)propanoic Acid

Description:

3-(2-Pyridyldithio)propanoic acid is an organosulfur compound characterized by the presence of a pyridine ring and a dithiocarboxylic acid functional group. This compound features a propanoic acid backbone, which is substituted at one end with a 2-pyridyldithio group. The presence of the pyridine ring imparts unique electronic properties, making it a potential ligand in coordination chemistry. The dithio group contributes to its reactivity, particularly in redox reactions and metal ion chelation. This compound is typically soluble in polar organic solvents and may exhibit moderate solubility in water due to the carboxylic acid group. Its chemical behavior can be influenced by pH, as the carboxylic acid can ionize, affecting its interactions in biological and chemical systems. Additionally, 3-(2-Pyridyldithio)propanoic acid may have applications in materials science, biochemistry, and as a building block in the synthesis of more complex molecules. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₈H₉NO₂S₂

InChI: InChI=1S/C8H9NO2S2/c10-8(11)4-6-12-13-7-3-1-2-5-9-7/h1-3,5H,4,6H2,(H,10,11)

InChI key: DJBRKGZFUXKLKO-UHFFFAOYSA-N

SMILES: C1=CC=NC(=C1)SSCCC(=O)O

Synonyms:

• 3-(2-Pyridyldithio)propionic acid-HCl (PDPA-HCl)
• 3-(2-Pyridinyldithio)propanoic Acid
• 3-(PYRIDIN-2-YLDITHIO)PROPANOIC ACID
• 3-(Pyridin-2-yldisulfanyl)propanoic acid
• 3-(2-Pyridyldithio)propanoic Acid
• 2-Carboxyethyl 2-Pyridyl Disulfide
• 3-(2-Pyridyldithio)propionic acid

3-(2-Pyridyldithio)propionic Acid

CAS: 68617-64-1

Formula: C₈H₉NO₂S₂

Purity: >97.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 215.29

Ref: 3B-P2668

3-(2-Pyridyldithio)propanoic Acid

CAS: 68617-64-1

Formula: C₈H₉NO₂S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 215.2926

Ref: IN-DA005P8U

3-(2-pyridyldithio)propionic acid

CAS: 68617-64-1

3-(2-pyridyldithio)propionic acid

Formula: C₈H₉NO₂S₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 215.296

Ref: 54-OR97191

3-(2-Pyridyldithio)propanoic Acid

CAS: 68617-64-1

3-(2-Pyridyldithio)propanoic Acid is a heterobifunctional PROTAC linker with a disulfide for thiol reactions and a carboxyl for conjugation.

Formula: C₈H₉NO₂S₂

Purity: 99.04%

Color and Shape: Solid

Molecular weight: 215.29

Ref: TM-T14023

3-(2-Pyridyldithio)propanoic Acid

CAS: 68617-64-1

3-(Pyridin-2-yldisulfanyl)propanoic acid

Formula: C₈H₉NO₂S₂

Purity: 97%

Molecular weight: 215.29

Ref: IN-DG447548

SPDP acid

CAS: 68617-64-1

SPDP acid is a linker that forms reversible disulfide bonds with thiols on drugs or proteins. The cleavage occurs under intracellular reducing conditions. Its heterobifunctionality permits the formation of new disulfide bonds by reacting with free thiol groups on proteins (like cysteines) and also with amines.

Formula: C₈H₉NO₂S₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 215.29 g/mol

Ref: 3D-FP27337

3-(2-Pyridyldithio)propanoic acid

CAS: 68617-64-1

Formula: C₈H₉NO₂S₂

Purity: 95%

Color and Shape: Liquid

Molecular weight: 215.007

Ref: 10-F513564

3-(2-Pyridyldithio)propanoic Acid

Controlled Product

CAS: 68617-64-1

Applications Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes on polymeric carriers. Targeted delivery of a triplex-forming oligonucleotide to hepatic stellate cells by complexes with phosphated bovine serum albumin for treatment of liver fibrosis.
References Mahato, R., et al.: Biochem. Pharmacol., 53, 887 (1997), Weiner, J., et al.: J. Biol. Chem., 273, 15913 (1998), Ye, Z., et al.: Biochem., 44, 4466 (2005).

Formula: C₈H₉NO₂S₂

Color and Shape: Neat

Molecular weight: 215.29

Ref: TR-P993030