CAS 68745-38-0
:5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
Description:
5,7-Dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one, also known as a flavonoid compound, exhibits several notable characteristics. This substance features a chromone backbone, which is a fused benzopyran structure, and is substituted with hydroxyl groups at the 5 and 7 positions, contributing to its potential antioxidant properties. The presence of the phenyl group at the 2 position enhances its biological activity and solubility in organic solvents. This compound is often studied for its pharmacological effects, including anti-inflammatory, antimicrobial, and anticancer activities, attributed to its ability to scavenge free radicals and modulate various biochemical pathways. Its structural features also suggest potential interactions with biological macromolecules, making it a candidate for further research in medicinal chemistry. Additionally, the compound's stability and reactivity can be influenced by the hydroxyl groups, which may participate in hydrogen bonding and affect its solubility in different solvents. Overall, 5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one represents a significant area of interest in the study of natural products and their therapeutic applications.
Formula:C15H12O4
InChI:InChI=1/C15H12O4/c16-10-6-12(17)11-8-13(18)15(19-14(11)7-10)9-4-2-1-3-5-9/h1-7,15-17H,8H2
SMILES:c1ccc(cc1)C1C(=O)Cc2c(cc(cc2O1)O)O
Synonyms:- 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-
- 5,7-Dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-on
- 5,7-Dihydroxy-2-Phenyl-Chroman-3-One
- Pinocembrin
- 5,7-Dihydroxy-2-phényl-2,3-dihydro-4H-chromén-4-one
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.
(+/-)-Pinocembrin
CAS:(+/-)-Pinocembrin analytical standard provided with w/w absolute assay, to be used for quantitative titration.Formula:C15H12O4Purity:(HPLC) ≥98%Color and Shape:PowderMolecular weight:256.26(+/-)-Pinocembrin
CAS:(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.Formula:C15H12O4Purity:99.69%Color and Shape:SolidMolecular weight:256.25(±)-Pinocembrin
CAS:5,7-Dihydroxy-2-phenylchroman-4-oneFormula:C15H12O4Purity:97%Molecular weight:256.25Pinocembrin
CAS:Oxygen-heterocyclic compoundFormula:C15H12O4Purity:≥ 98.0 % (HPLC)Color and Shape:PowderMolecular weight:256.26rac-Pinocembrin
CAS:Controlled ProductApplications Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c.
References Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008); Liu, R. et al.: Brain Res., 1216, 104 (2008); Gao, M. et al.: Eur. J. Pharmacol., 591, 73 (2008);Formula:C15H12O4Color and Shape:NeatMolecular weight:256.25Pinocembrin
CAS:Pinocembrin is a flavonoid compound, which is a type of polyphenolic molecule, extracted primarily from honey, propolis, and various plants. It is characterized by its unique structure allowing it to function effectively as an antioxidant. The mode of action of Pinocembrin involves scavenging free radicals and reducing oxidative stress, which contributes to its protective effects on cells and tissues.Formula:C15H12O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:256.25 g/mol
