CAS 68858-20-8

FMOC-L-valine

Description:

FMOC-L-valine, with the CAS number 68858-20-8, is a derivative of the amino acid valine, modified with a 9-fluorenylmethoxycarbonyl (FMOC) protecting group. This compound is commonly used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), due to its ability to protect the amino group of the amino acid during the coupling reactions. FMOC-L-valine is typically a white to off-white solid, and it is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. The FMOC group can be removed under mild basic conditions, allowing for the subsequent coupling of the amino acid to other peptide fragments. The presence of the branched-chain aliphatic side chain characteristic of valine contributes to the hydrophobic properties of the resulting peptides. Overall, FMOC-L-valine is an important building block in the field of peptide chemistry, facilitating the synthesis of various biologically active peptides and proteins.

Formula: C₂₀H₂₁NO₄

InChI: InChI=1S/C20H21NO4/c1-12(2)18(19(22)23)21-20(24)25-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17-18H,11H2,1-2H3,(H,21,24)(H,22,23)/t18-/m0/s1

InChI key: InChIKey=UGNIYGNGCNXHTR-SFHVURJKSA-N

SMILES: C(OC(N[C@@H](C(C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• (2S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-3-methylbutanoic acid
• (9-Fluorenylmethoxycarbonyl)valine
• (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoic acid
• (S)-N-Fmoc-valine
• 125: PN: WO2004099237 PAGE: 36 claimed protein
• 221: PN: US20070042401 PAGE: 29 claimed protein
• 912: PN: WO2006135786 PAGE: 59 claimed protein
• <span class="text-smallcaps">L</span>-Valine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-<span class="text-smallcaps">L</span>-valine
• FMOC-L-valine
• Fmoc-L-Val-OH
• Fmoc-valine
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-valine
• N-(9-Fluorenylmethoxycarbonyl)-L-valine
• N-(9-Fluorenylmethoxycarbonyl)valine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-valine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valin
• N-[(9H-fluoren-9-ilmetoxi)carbonil]-L-valina
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valine
• N-[(9H-fluorene-9-ylmethoxy)carbonyl]-L-valine
• Nsc 334304

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-valine

CAS: 68858-20-8

Formula: C₂₀H₂₁NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 339.39

Ref: 3B-F0299

N-Fmoc-L-valine, 98%

CAS: 68858-20-8

It is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Fmoc-valine (in addition to the other amino acids) is commonly used to synthesize 4-thiazolidinones (e.g. (E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one [E925745]) and 4-metathiazanones as well. This

Formula: C₂₀H₂₁NO₄

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 339.39

Ref: 02-B21030

Fmoc-Val-OH

CAS: 68858-20-8

M03378 - Fmoc-Val-OH

Formula: C₂₀H₂₁NO₄

Purity: 98%

Color and Shape: Solid, Crystalline or Powder

Molecular weight: 339.391

Ref: 10-M03378

Fmoc-L-valine

CAS: 68858-20-8

Formula: C₂₀H₂₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 339.3850

Ref: IN-DA0036PX

Fmoc-Val-OH

CAS: 68858-20-8

Formula: C₂₀H₂₁NO₄

Purity: ≥ 99.0%

Color and Shape: White powder

Molecular weight: 339.39

Ref: 7W-GM1305

L-Valine, N-FMOC protected

CAS: 68858-20-8

L-Valine, N-FMOC protected

Formula: C₂₀H₂₁NO₄

Purity: 98%

Color and Shape: white powder

Molecular weight: 339.39g/mol

Ref: 54-OR0495

Fmoc-Val-OH

CAS: 68858-20-8

Fmoc-Val-OH is an amino acid that is synthesized in a solid phase synthesis and purified by column chromatography. It has a molecular weight of 168.0 and chemical formula C6H8O2N2S2. Fmoc-Val-OH has been shown to inhibit the enzyme activity of protein phosphatase 1, which is involved in cancer cell proliferation, tumor growth and metastasis. Fmoc-Val-OH is also used as a substrate for peptide synthesis and amide bond formation with various reagents such as trifluoroacetic acid and dicyclohexylcarbodiimide (DCC).

Formula: C₂₀H₂₁NO₄

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 339.39 g/mol

Ref: 3D-FF15880

Fmoc-Val-OH

CAS: 68858-20-8

Please enquire for more information about Fmoc-Val-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₀H₂₁NO₄

Purity: Min. 98.0 Area-%

Molecular weight: 339.39 g/mol

Ref: 3D-FLV-1739-PI

FMOC-L-Valine extrapure, 99%

CAS: 68858-20-8

Formula: C₂₀H₂₁NO₄

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 339.40

Ref: SR-47834

Fmoc-valine

Controlled Product

CAS: 68858-20-8

Applications Fmoc-valine is a sterically hindered, Fmoc protected amino acid and is a derivative of L-Valine (V094205). Fmoc-valine (in addition to the other amino acids) is commonly used to synthesize 4-thiazolidinones (e.g. (E)-5-(4-Ethylbenzylidene)-2-thioxothiazolidin-4-one [E925745]) and 4-metathiazanones as well.
References Bernatowicz, M., et al.: Tetrahed. Lett., 30, 4645 (1989); Holmes, C., et al.: J. Org. Chem., 60, 7328 (1995)

Formula: C₂₀H₂₁NO₄

Color and Shape: Neat

Molecular weight: 339.39

Ref: TR-F680000

Fmoc-Val-OH

CAS: 68858-20-8

Formula: C₂₀H₂₁NO₄

Molecular weight: 339.4

Ref: ST-EA-CP-L28027

Fmoc-Val-OH

CAS: 68858-20-8

Bachem ID: 4093145.

Formula: C₂₀H₂₁NO₄

Purity: 99.9%

Color and Shape: White

Molecular weight: 339.39

Ref: 01-4093145