CAS 68982-90-1

N-(3-Carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-L-phenylalaninamide

Description:

N-(3-Carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-L-phenylalaninamide, with the CAS number 68982-90-1, is a synthetic compound that belongs to the class of peptides and amides. This substance features a complex structure characterized by the presence of multiple functional groups, including carboxylic acid, amide, and nitro groups, which contribute to its chemical reactivity and potential biological activity. The compound is likely to exhibit solubility in polar solvents due to its ionic and polar functional groups. Its structure suggests potential applications in medicinal chemistry, particularly in drug design, where modifications to peptide sequences can enhance biological activity or specificity. The presence of the nitrophenyl group may also impart unique optical properties, making it useful in various analytical applications. Overall, this compound's intricate structure and functional diversity make it a subject of interest in both research and pharmaceutical development.

Formula: C₂₃H₂₅N₅O₈

InChI: InChI=1S/C23H25N5O8/c29-19(10-11-22(32)33)24-13-20(30)25-14-21(31)27-18(12-15-4-2-1-3-5-15)23(34)26-16-6-8-17(9-7-16)28(35)36/h1-9,18H,10-14H2,(H,24,29)(H,25,30)(H,26,34)(H,27,31)(H,32,33)/t18-/m0/s1

InChI key: InChIKey=CFYIUBWVKZQDOG-SFHVURJKSA-N

SMILES: [C@H](CC1=CC=CC=C1)(C(NC2=CC=C(N(=O)=O)C=C2)=O)NC(CNC(CNC(CCC(O)=O)=O)=O)=O

Synonyms:

• (S)-4-((2-((2-((1-((4-Nitrophenyl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-2-oxoethyl)amino)-2-oxoethyl)amino)-4-oxobutanoic acid
• 4-[[2-[[2-[[(1S)-1-benzyl-2-[(4-nitrophenyl)amino]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-2-oxo-ethyl]amino]-4-oxo-butanoic acid
• 42: PN: CN101457218 PAGE: 2 claimed protein
• <span class="text-smallcaps">L</span>-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-
• Chymotrypsin Substrate I, Colorimetric
• L-Phenylalaninamide, N-(3-carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-
• N-(3-Carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-<span class="text-smallcaps">L</span>-phenylalaninamide
• N-Succinylglycyl-phenylalanine-4-nitroanilide
• Suc-Gly-Gly-Phe-Pna
• N-(3-Carboxypropionyl)glycylglycyl-N-(p-nitrophenyl)-3-phenyl-L-alaninamide
• N-(3-Carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-L-phenylalaninamide
• SUC-GGF-PNA
• 3-carboxypropanoylglycyl-glycyl-phenylalanine p-nitroanilide

Suc-Gly-Gly-Phe-pNA

CAS: 68982-90-1

Suc-GGF-pNA was used to determine the activity of chymotrypsin and of Streptomyces griseus protease B.

Formula: C₂₃H₂₅N₅O₈

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 499.48

Ref: 01-4002298

N-(3-Carboxy-1-oxopropyl)glycylglycyl-N-(4-nitrophenyl)-L-phenylalaninamide

Controlled Product

CAS: 68982-90-1

Applications Chymotrypsin Substrate I, Colorimetric is a substrate for the assay of chymotrypsin activity and for S. griseus protease B. Contains 90 mg D-mannitol and 10 mg substrate.
References Achstetter, T., et al. 1981. Arch. Biochem. Biophys. 207: 445-454; Shinar, S. and Gertler, A. 1979. Int. J. Pept. Protein Res. 13: 218-222

Formula: C₂₃H₂₅N₅O₈

Color and Shape: Neat

Molecular weight: 499.47

Ref: TR-C432860

Suc-Gly-Gly-Phe-pNA

CAS: 68982-90-1

Suc-Gly-Gly-Phe-pNA is a colorimetric substrate for Chymotrypsin and Streptomyces griseus protease B. Activity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm.

Formula: C₂₃H₂₅N₅O₈

Purity: Min. 95%

Molecular weight: 499.47 g/mol

Ref: 3D-FS110740