CAS 6902-91-6

Germacrone

Description:

Germacrone, with the CAS number 6902-91-6, is a naturally occurring sesquiterpene compound primarily found in various essential oils, particularly those derived from plants in the Asteraceae family. It is characterized by its bicyclic structure, which contributes to its unique chemical properties. Germacrone exhibits a pleasant, aromatic scent, making it valuable in the fragrance and flavor industries. Additionally, it has been studied for its potential biological activities, including anti-inflammatory, antimicrobial, and antioxidant properties. The compound is typically a colorless to pale yellow liquid at room temperature and is soluble in organic solvents. Its stability and reactivity can be influenced by environmental factors such as temperature and light. Germacrone's applications extend beyond perfumery; it is also explored in traditional medicine and as a potential lead compound in pharmaceutical research. Overall, germacrone represents a significant interest in both natural product chemistry and applied sciences due to its diverse properties and potential uses.

Formula: C₁₅H₂₂O

InChI: InChI=1/C15H22O/c1-11(2)14-9-8-12(3)6-5-7-13(4)10-15(14)16/h7-8H,5-6,9-10H2,1-4H3/b12-8+,13-7+

InChI key: InChIKey=CAULGCQHVOVVRN-SWZPTJTJSA-N

SMILES: C(C)(C)=C1C(=O)C\C(\C)=C\CC\C(\C)=C\C1

Synonyms:

• (3E,7E)-3,7-Dimethyl-10-(1-methylethylidene)-3,7-cyclodecadien-1-one
• (3E,7E)-3,7-dimethyl-10-(1-methylethylidene)cyclodeca-3,7-dien-1-one
• (3Z,7E)-3,7-dimethyl-10-(1-methylethylidene)cyclodeca-3,7-dien-1-one
• (3Z,7Z)-3,7-Dimethyl-10-Propan-2-Ylidene-Cyclodeca-3,7-Dien-1-One
• (E,E)-Germacra-3,7(11),9-trien-6-one
• (E,E)-Germacrone
• 3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (3E,7E)-
• 3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-, (E,E)-
• Germacra-3,7(11),9-trien-6-one, (E,E)-
• Germacron
• Germacrone
• Germacrone, 98%, from Curcuma zedoaria (Christm.) Rosc
• (3E,7E)-3,7-Dimethyl-10-isopropylidene-3,7-cyclodecadien-1-one
• (3E,7E)-3,7-DiMethyl-10-(propan-2-ylidene)cyclodeca-3,7-dienone
• trans,trans-3,7-Dimethyl-10-isopropylidene-3,7-cyclodecadien-1-one
• 3,7-Dimethyl-10-(1-methylethylidene)-3,7-cyclodecadien-1-one
• (E,E)-3,7-Dimethyl-10-(1-methylethylidene)-3,7-cyclodecadien-1-one
• GERMACRONE(RG)
• (3E,7E)-10-Isopropylidene-3,7-diMethyl-3,7-cyclodecadien-1-one
• (3E,7E)-3,7-dimethyl-10-propan-2-ylidenecyclodeca-3,7-dien-1-one

Germacrone

CAS: 6902-91-6

Formula: C₁₅H₂₂O

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 218.34

Ref: 3B-G0519

3,7-Cyclodecadien-1-one, 3,7-dimethyl-10-(1-methylethylidene)-,(3E,7E)-

CAS: 6902-91-6

Formula: C₁₅H₂₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 218.3346

Ref: IN-DA00IBW5

Germacrone

CAS: 6902-91-6

Germacrone

Purity: ≥98%

Molecular weight: 218.33g/mol

Ref: 54-BUP13321

Germacrone

CAS: 6902-91-6

Formula: C₁₅H₂₂O

Molecular weight: 218.34

Ref: 7W-GY4015

Germacrone

CAS: 6902-91-6

Germacrone

Purity: 98%

Molecular weight: 218.339g/mol

Ref: 54-OR1026322

Germacrone

CAS: 6902-91-6

Germacrone, a natural product isolated from Rhizoma curcuma, can inhibit the proliferation of breast cancer cell lines by inducing cell cycle arrest and apoptosis through mitochondria-mediated caspase pathway.

Formula: C₁₅H₂₂O

Purity: 95%~99%

Color and Shape: Cryst.

Molecular weight: 218.34

Ref: BP-BP0641

Germacrone

CAS: 6902-91-6

Formula: C₁₅H₂₂O

Molecular weight: 218.34

Ref: 4Z-S-178014

Germacrone

CAS: 6902-91-6

Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities.

Formula: C₁₅H₂₂O

Purity: 98.81% - 99.95%

Color and Shape: Solid

Molecular weight: 218.33

Ref: TM-T2945

Germacrone

CAS: 6902-91-6

Alicyclic ketone

Formula: C₁₅H₂₂O

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 218.34

Ref: 5G-89677

Germacrone (>90%)

Controlled Product

CAS: 6902-91-6

Stability Light Sensitive
Applications Germacrone is an antiviral isolate of Geranium macrorrhizum which inhibits and prevents early stage influenza virus infection. It also inhibits the proliferation of glioma cells by promoting apoptosis.
References Liao, Q. et al.: Antiviral. Res., 100, 578 (2013); Liu, B. et al.: Mol. Med. Reports., 10, 1046 (2014);

Formula: C₁₅H₂₂O

Purity: >90%

Color and Shape: Neat

Molecular weight: 218.33

Ref: TR-G367755

Germacrone

CAS: 6902-91-6

Germacrone is a bioactive sesquiterpene compound, which is primarily derived from the essential oils of plants belonging to the genus *Curcuma*, such as *Curcuma zedoaria*. It is known for its diverse pharmacological activities. The mode of action of Germacrone involves the modulation of various signaling pathways, including anti-inflammatory and apoptotic pathways. It exhibits effects by inhibiting NF-κB activity, inducing apoptosis, and exerting anti-tumor properties.

Formula: C₁₅H₂₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 218.33 g/mol

Ref: 3D-FG41654