CAS 69024-84-6

Glycinamide,N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-

Description:

Glycinamide, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]- is a complex organic compound characterized by its multi-functional structure, which includes amino acid components and a naphthalene derivative. This compound features a sulfonamide group, which enhances its solubility and reactivity, making it potentially useful in pharmaceutical applications. The presence of dimethylamino and chloroacetyl groups suggests that it may exhibit biological activity, possibly as an inhibitor or modulator in biochemical pathways. Its structure indicates that it could interact with various biological targets, including enzymes or receptors, due to the presence of multiple functional groups. The compound's molecular weight, solubility, and stability would depend on its specific structural features and the conditions under which it is studied. As with many complex organic molecules, its synthesis and characterization would require careful analytical techniques to confirm purity and structural integrity.

Formula: C₂₆H₃₆ClN₇O₇S

Synonyms:

• Glycinamide,N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-(9CI)
• Glycinamide, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-,(S)-
• Dansylglutamyl-Glycyl-Arginine Chloromethyl Ketone
• Glycinamide, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-α-glutamyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-
• Dansyl-Glu-Gly-Arg-CMK
• Dansyl-Glu-Gly-Arg-chloromethylketone

Dansyl-Glu-Gly-Arg-chloromethylketone

CAS: 69024-84-6

Irreversible inhibitor of plasminogen activator, Factor Xa and urokinase. Dns-EGR-CMK allows direct monitoring of interactions of labeled enzyme.

Formula: C₂₆H₃₆ClN₇O₇S

Purity: 94.1%

Color and Shape: Yellow

Molecular weight: 626.13

Ref: 01-4050449

Dansyl-Glu-Gly-Arg-Chloromethylketone

CAS: 69024-84-6

Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activated

Formula: C₂₆H₃₆ClN₇O₇S

Color and Shape: Solid

Molecular weight: 626.12

Ref: TM-T80094

Dansyl-Glu-Gly-Arg-chloromethylketone

CAS: 69024-84-6

Dansyl-Glu-Gly-Arg-chloromethylketone is a fluorescent substrate for epidermal growth factor (EGF). It has been shown to inhibit the proteolytic activity of EGF. This inhibition is due to the binding of Dansyl-Glu-Gly-Arg-chloromethylketone to calcium and its inhibitory properties on EGF. The flow system used in this experiment was activated with a monoclonal antibody, which binds to the cytosolic calcium and activates the enzyme. The kinetic data obtained from this experiment showed that the rate of EGF hydrolysis by Dansyl-Glu-Gly-Arg-chloromethylketone was proportional to the concentration of calcium in the cytosol.

Formula: C₂₆H₃₆ClN₇O₇S

Purity: Min. 95%

Molecular weight: 626.13 g/mol

Ref: 3D-FD111116