CAS 692737-80-7

Formula: C24H27FN6O4

InChI: InChI=1S/C21H21FN6O.C3H6O3/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29;1-2(4)3(5)6/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29);2,4H,1H3,(H,5,6)

InChI key: ZRHDKBOBHHFLBW-UHFFFAOYSA-N

SMILES: CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N

4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate

CAS: 692737-80-7

Formula: C₂₄H₂₇FN₆O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 482.5074

Ref: IN-DA006NEX

Dovitinib lactate

CAS: 692737-80-7

Dovitinib lactate

Formula: C₂₄H₂₇FN₆O₄

Purity: ≥98%

Molecular weight: 482.51

Ref: 54-BUP15512

Dovitinib lactate

CAS: 692737-80-7

Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).

Formula: C₂₄H₂₇FN₆O₄

Purity: 99.54% - 99.77%

Color and Shape: Solid

Molecular weight: 482.51

Ref: TM-T7104

Dovitinib Lactate Salt

CAS: 692737-80-7

Dovitinib Lactate Salt

Formula: C₂₁H₂₁FN₆O·C₃H₆O₃

Purity: 99.98% (Typical Value in Batch COA)

Color and Shape: Tan Solid-Crystals

Molecular weight: 482.50738

Ref: 54-BIFK0016

Dovitinib lactate

CAS: 692737-80-7

4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate

Formula: C₂₄H₂₇FN₆O₄

Purity: 99%

Molecular weight: 482.51

Ref: IN-DG216013

Dovitinib Lactate Salt

CAS: 692737-80-7

Dovitinib is a tyrosine kinase inhibitor that is used for the treatment of non-small cell lung cancer, renal cell carcinoma and other cancers. Dovitinib inhibits tumor growth by blocking the cell factor (c-KIT) and the stem cell factor receptor (c-MET). It also inhibits tumor angiogenesis through its inhibition of the colony-stimulating factor 1 receptor (CSF1R), which is involved in regulating hematopoietic stem cells. Dovitinib has been shown to inhibit tumor growth by blocking antiapoptotic genes, such as Bcl2, BclxL, Bfl-1 and Mcl-1. This drug has a terminal half-life of 15 hours.

Formula: C₂₄H₂₇FN₆O₄

Purity: Min. 95%

Molecular weight: 482.51 g/mol

Ref: 3D-SCB73780

Dovitinib Lactate

Controlled Product

CAS: 692737-80-7

Applications Dovitinib is used in treating melanoma.
References Renhowe, P., et al.: J. Med. Chem., 52, 278 (2009),

Formula: C₂₁H₂₁FN₆O·C₃H₆O₃

Color and Shape: Neat

Molecular weight: 482.5

Ref: TR-D537000