CAS 69388-79-0

Sulbactam pivoxil

Description:

Sulbactam pivoxil is a synthetic beta-lactamase inhibitor that is primarily used in combination with beta-lactam antibiotics to enhance their efficacy against resistant bacterial strains. It is a prodrug of sulbactam, which means it is converted into its active form in the body. The compound is characterized by its ability to inhibit a wide range of beta-lactamases, enzymes produced by bacteria that confer resistance to penicillins and cephalosporins. Sulbactam pivoxil is typically administered orally and is known for its favorable pharmacokinetic properties, including good absorption and distribution in the body. The substance is generally well-tolerated, with a safety profile similar to that of other beta-lactam antibiotics. Its chemical structure includes a beta-lactam ring, which is essential for its mechanism of action, and it is often used in clinical settings to treat infections caused by susceptible organisms, particularly in cases where resistance is a concern.

Formula: C₁₄H₂₁NO₇S

InChI: InChI=1S/C14H21NO7S/c1-13(2,3)12(18)22-7-21-11(17)10-14(4,5)23(19,20)9-6-8(16)15(9)10/h9-10H,6-7H2,1-5H3/t9-,10+/m1/s1

InChI key: InChIKey=OHPVYKXTRACOSQ-ZJUUUORDSA-N

SMILES: C(OCOC(C(C)(C)C)=O)(=O)[C@@H]1N2[C@](S(=O)(=O)C1(C)C)(CC2=O)[H]

Synonyms:

• (Pivaloyloxy)methyl penicillanate S,S-dioxide
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, 4,4-dioxide, (2S,5R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, 4,4-dioxide, (2S-cis)-
• Cp 47904
• Sulbactam Pivoxil
• Unasyn Oral
• [(2,2-Dimethylpropanoyl)Oxy]Methyl 3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate 4,4-Dioxide
• [(2,2-dimethylpropanoyl)oxy]methyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester,4,4-dioxide, (2S,5R)-

CAS: 69388-79-0

Formula: C₁₄H₂₁NO₇S

Purity: 98%

Color and Shape: Solid

Molecular weight: 347.3840

Ref: IN-DA00IBXM

Sulbactam Pivoxil

CAS: 69388-79-0

Formula: C₁₄H₂₁NO₇S

Color and Shape: White To Off-White Solid

Molecular weight: 347.38

Ref: 4Z-S-468

(2S,5R)-(Pivaloyloxy)Methyl 3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate 4,4-Dioxide

CAS: 69388-79-0

(2S,5R)-(Pivaloyloxy)Methyl 3,3-Dimethyl-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptane-2-Carboxylate 4,4-Dioxide

Purity: 98%

Molecular weight: 347.38g/mol

Ref: 54-OR1030487

Sulbactam pivoxil

CAS: 69388-79-0

Sulbactam pivoxil is a prodrug of sulbactam, exhibiting oral bioavailability and superior absorption. Sulbactam functions as a β-lactamase inhibitor.

Formula: C₁₄H₂₁NO₇S

Purity: 99.68%

Color and Shape: Solid

Molecular weight: 347.38

Ref: TM-T1631L

Sulbactam Pivoxil

CAS: 69388-79-0

Formula: C₁₄H₂₁NO₇S

Molecular weight: 347.38

Ref: ST-EA-CP-S63008

Sulbactam Pivoxil

CAS: 69388-79-0

Applications Sulbactam Pivoxil is a prodrug of the semi-synthetic β-lactamase inhibitor Sulbactam (S699195).
References Foulds, G. et al.: Curr. Chemother. Infect. Dis., Proc. Int. Congr. Chemother., 11, 353 (1980); Pei, Q. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 879, 2000 (2011);

Formula: C₁₄H₂₁NO₇S

Color and Shape: Off-White

Molecular weight: 347.38

Ref: TR-S699190

Sulbactam pivoxil

CAS: 69388-79-0

Purity: 98%(LC-MS);RG

Molecular weight: 347.3800049

Ref: 10-F601277

Sulbactam pivoxyl

CAS: 69388-79-0

**Sulbactam pivoxyl** is a prodrug, which is a chemically modified form of sulbactam intended to improve its pharmacokinetic properties. Sulbactam itself is a beta-lactamase inhibitor of synthetic origin, specifically designed to combat antibiotic resistance by inhibiting the beta-lactamase enzymes produced by certain bacteria. These enzymes typically break down beta-lactam antibiotics, rendering them ineffective.

Formula: C₁₄H₂₁NO₇S

Purity: Min. 95%

Molecular weight: 347.38 g/mol

Ref: 3D-UCA38879