CAS 70-18-8

Glutathione

Description:

Glutathione, with the CAS number 70-18-8, is a tripeptide composed of three amino acids: glutamine, cysteine, and glycine. It is a crucial antioxidant found in nearly all living cells, playing a vital role in protecting cells from oxidative stress and maintaining the redox state. Glutathione exists in two forms: reduced (GSH) and oxidized (GSSG), with the reduced form being the active antioxidant. It is involved in various biochemical processes, including detoxification, protein synthesis, and the regulation of cellular functions. Glutathione is soluble in water and has a relatively low molecular weight. Its antioxidant properties are attributed to the thiol group in cysteine, which can donate electrons to neutralize free radicals. Additionally, glutathione is important in the metabolism of drugs and toxins, facilitating their excretion from the body. Deficiencies in glutathione levels have been linked to various health issues, including neurodegenerative diseases and immune dysfunction, highlighting its significance in human health and disease prevention.

Formula: C₂₀H₃₂N₆O₁₂S₂

InChI: InChI=1/C10H17N3O6S/c11-5(1-2-7(14)15)9(18)13-6(4-20)10(19)12-3-8(16)17/h5-6,20H,1-4,11H2,(H,12,19)(H,13,18)(H,14,15)(H,16,17)

InChI key: InChIKey=RWSXRVCMGQZWBV-WDSKDSINSA-N

SMILES: [C@H](C(NCC(O)=O)=O)(NC(CC[C@@H](C(O)=O)N)=O)CS

Synonyms:

• 5-L-Glutamyl-L-Cysteinylglycine
• <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-cysteinylglycine
• <span class="text-smallcaps">L</span>-Glutathione
• Agifutol S
• Antisense compounds
• Atomolan
• Bakezyme RX
• Copren
• Deltathione
• GSH
• Gamma-Glutamylcysteinylglycine
• Glutathion
• Glutathione reduced
• Glutathione, Reduced, Free Acid
• Glutathione-SH
• Glutation
• Glutide
• Glutinal
• Glycine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl-
• Glycine, L-γ-glutamyl-L-cysteinyl-
• Glycine, N-(N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl)-
• Glycine, N-(N-L-γ-glutamyl-L-cysteinyl)-
• High Thione Extract YH 15
• Isethion
• L-Glutathione
• L-Glutathione (Reduced Form)
• L-Glutathione Reduced
• L-gamma-glutamyl-3-sulfido-L-alanylglycine
• L-gamma-glutamyl-L-cysteinylglycine
• N-(N-<span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-cysteinyl)glycine
• N-(N-L-γ-Glutamyl-L-cysteinyl)glycine
• N⁵-((R)-1-((Carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)-<span class="text-smallcaps">L</span>-glutamine
• Neuthion
• ReadiSorb
• Reduced glutathione
• ReducedGlutathione
• Tad 600
• Tathion
• Tathione
• Triptide
• gamma-L-Glutamyl-L-cysteinylglycine
• {[N-(2-ammonio-4-carboxybutanoyl)cysteinyl]amino}acetate
• γ-<span class="text-smallcaps">L</smallcap>-Glutamyl-<smallcap>L</span>-cysteinylglycine
• γ-Glutamyl-cysteinyl-glycine
• γ-Glutamylcysteinylglycine
• γ-L-Glutamyl-L-cysteinylglycine
• L-γ-Glutamyl-L-cysteinylglycine
• Glutathione
• G-L-GLUTAMYL-L-CYSTEINGLYCINE
• GAMMA-L-GLUTAMYL-L-CYSTEINYL-GLYCINE
• GAMMA-L-GLUTAMYL-CYSTEINYL GLYCINE
• GSI
• GAMMA-L-GLUTAMYL-L-CYSTEINYGLYCINE
• H-GAMMA-GLU-CYS-GLY-OH
• GLUTATHIONE REDUCED FORM
• GAMMA-GLU-CYS-GLY
• GLUTATHION (REDUCED)
• GLUTAMYLCYSTEINYLGLYCINE, REDUCED

Glutathione reduced form

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: >97.0%(T)

Color and Shape: White powder to crystal

Molecular weight: 307.32

Ref: 3B-G0074

L-Glutathione, reduced, 97%

CAS: 70-18-8

L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfid

Formula: C₁₀H₁₇N₃O₆S

Purity: 97%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 307.32

Ref: 02-A18014

L-Glutathione, reduced, 98+%

CAS: 70-18-8

A tripeptide used for reductive cleavage of disulfide bonds

Formula: C₁₀H₁₇N₃O₆S

Purity: 98+%

Color and Shape: White, Crystalline powder

Molecular weight: 307.32

Ref: 02-J62166

GLUTATHIONE CRS

CAS: 70-18-8

GLUTATHIONE CRS

Formula: C₁₀H₁₇N₃O₆S

Molecular weight: 307.3235

Ref: 41-Y0000517

Glutathione

CAS: 70-18-8

Other organo-sulfur acid compounds

Formula: C₁₀H₁₇N₃O₆S

Color and Shape: White Powder

Molecular weight: 307.08381

Ref: 45-1294820

L-Glutathione reduced

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 307.3235

Ref: IN-DA006BC6

L-Glutathione reduced

CAS: 70-18-8

L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.

Formula: C₁₀H₁₇N₃O₆S

Purity: 97.37% - 99.99%

Color and Shape: Solid

Molecular weight: 307.32

Ref: TM-T1085

Glutathione

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Color and Shape: White To Off-White Solid

Molecular weight: 307.32

Ref: 4Z-PG-257

Glutathione reduced

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: ≥ 98.0%

Color and Shape: White crystalline powder

Molecular weight: 307.33

Ref: 7W-GE1520

L-Glutathione reduced

CAS: 70-18-8

L-Glutathione reduced

Purity: ≥95%

Molecular weight: 307.32g/mol

Ref: 54-BUP19622

(L)-Glutathione (reduced form)

CAS: 70-18-8

(L)-Glutathione (reduced form)

Formula: C₁₀H₁₇N₃O₆S

Purity: 97% (Typical Value in Batch COA)

Color and Shape: white solid

Molecular weight: 307.32348g/mol

Ref: 54-BIB6314

Glutathione

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Color and Shape: Neat

Molecular weight: 307.32

Ref: 04-C14035100

Glutathione

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: 95%~99%

Molecular weight: 307.321

Ref: BP-SBP03306

Glutathione

Controlled Product

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Color and Shape: Neat

Molecular weight: 307.32

Ref: 86-MM1025.00

Glutathione

Controlled Product

CAS: 70-18-8

Stability Hygroscopic
Applications Glutathione may decrease the concentrations of inflammatory cytokines (IL-6, IL-18), neutrophils in lung tissue and increase the level of serum Ca2+ and be useful for the treatment of ANP. Glutathione production is regulated via distinct pathways in stressed and non-stressed cortical neurons. This compound has neuroprotective properties.
References Misko, T., et al.: J. Biol. chem., 273, 15646 (1998), Nakamura, K., et al.: J. Biol. Chem., 276, 34402 (2001) , Burdo, J., et al.: Brain Res. 1189, 12 (2008).

Formula: C₁₀H₁₇N₃O₆S

Color and Shape: Off-White

Molecular weight: 307.32

Ref: TR-G597951

Glutathione (Glycine-13C2,15N) Trifluoroacetate

CAS: 70-18-8, 815610-65-2

Stability Hygroscopic
Applications Glutathione-glycine-13C2,15N Trifluoroacetate Salt is the labelled disodium salt derivative of Glutathione (G597951), a tripeptide thiol (composed of L-Cysteine [C995015], Glycine [G615990] and Glutamate) that is found in all cells, possesses an important role in metabolism and protects against reactive oxygen species in the body.
References Cooper, A. & Kristal, B.: Biol. Chem., 378, 793 (1997); Meister, A.: Science, 220, 472 (1983);

Formula: C₈₁₃C₂H₁₇N₂₁₅NO₆S•C₂HF₃O₂

Color and Shape: Neat

Molecular weight: 310.3011402

Ref: TR-G597954

L-Glutathione, reduced

CAS: 70-18-8

Glutathione is a tripeptide cysteine-glycine-glutamic acid which exists in cells in the reduced form (this product) or oxidised form. Reduced glutathione (GSH) is an antioxidant protecting cell components from endogenous and exogeneous reactive oxygen and nitrogen species. Reduced glutathione has also been intensely used in the affinity purification of proteins with glutathione S-transferase (GST) tag. In the protein purification process, glutathione is used for the elution of GST-fused recombinant proteins from a glutathione-immobilised resins. In the elution buffers, reduced glutathione is typically used in the 10 – 40 mM concentration range.

Formula: C₁₀H₁₇N₃O₆S

Purity: Min. 98.0 Area-%

Molecular weight: 307.32 g/mol

Ref: 3D-G-3980

L-Glutathione, reduced

CAS: 70-18-8

Glutathione is a tripeptide cysteine-glycine-glutamic acid which exists in cells in the reduced form (this product) or oxidised form. Reduced glutathione (GSH) is an antioxidant protecting cell components from endogenous and exogeneous reactive oxygen and nitrogen species. Reduced glutathione has also been intensely used in the affinity purification of proteins with glutathione S-transferase (GST) tag. In the protein purification process, glutathione is used for the elution of GST-fused recombinant proteins from a glutathione-immobilised resins. In the elution buffers, reduced glutathione is typically used in the 10 – 40 mM concentration range.

Formula: C₁₀H₁₇N₃O₆S

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 307.32 g/mol

Ref: 3D-FG10640

L-Glutathione, reduced, tested to USP spec

CAS: 70-18-8

Glutathione is a tripeptide cysteine-glycine-glutamic acid which exists in cells in the reduced form (this product) or oxidised form. Reduced glutathione (GSH) is an antioxidant protecting cell components from endogenous and exogeneous reactive oxygen and nitrogen species. Reduced glutathione has also been intensely used in the affinity purification of proteins with glutathione S-transferase (GST) tag. In the protein purification process, glutathione is used for the elution of GST-fused recombinant proteins from a glutathione-immobilised resins. In the elution buffers, reduced glutathione is typically used in the 10 – 40 mM concentration range.

Formula: C₁₀H₁₇N₃O₆S

Purity: (Titration) 98.0 To 101.0%

Color and Shape: White Off-White Crystalline Powder

Molecular weight: 307.32 g/mol

Ref: 3D-FG61468

Glutathione Reduced (GSH) ExiPlus, Multi-Compendial, 98%

CAS: 70-18-8

Formula: C₁₀H₁₇N₃O₆S

Purity: min. 98.0 - 101%

Color and Shape: White or almost white, Crystalline powder /Crystals, Clear, Colourless

Molecular weight: 307.32

Ref: SR-77285