CAS 700-06-1

Indole-3-carbinol

Description:

Indole-3-carbinol (I3C) is a naturally occurring compound derived from the breakdown of glucobrassicin, a glucosinolate found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. It is characterized by its indole structure, which consists of a fused benzene and pyrrole ring. I3C is known for its potential health benefits, particularly in cancer prevention, as it may influence estrogen metabolism and exhibit anti-inflammatory properties. The compound is also recognized for its role as a phytonutrient, contributing to the health-promoting effects of cruciferous vegetables. In terms of physical properties, I3C is typically a white to pale yellow crystalline solid with low solubility in water but higher solubility in organic solvents. Its chemical formula is C9H9N, and it has a molecular weight of approximately 145.17 g/mol. I3C is also studied for its potential effects on various biological pathways, including apoptosis and cell cycle regulation, making it a subject of interest in nutritional and pharmaceutical research.

Formula: C₉H₉NO

InChI: InChI=1S/C9H9NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-5,10-11H,6H2

InChI key: InChIKey=IVYPNXXAYMYVSP-UHFFFAOYSA-N

SMILES: C(O)C=1C=2C(NC1)=CC=CC2

Synonyms:

• (1H-Indol-3-yl)methanol
• 1H-Indol-3-ylmethanol
• 1H-Indole-3-methanol
• 3-(Hydroxymethyl)indole
• 3-Indole methanol
• 3-Indolemethanol
• 3-Indolylcarbinol
• 3-Indolylmethanol
• Akos Ncg1-0099
• I3C
• Indinol
• Indo-3-Carbinol
• Indole-3-methanol
• Indolemethanol
• NSC 525801

3-Indolemethanol

CAS: 700-06-1

Formula: C₉H₉NO

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 147.18

Ref: 3B-I0496

3-Indolemethanol, 97%

CAS: 700-06-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₉NO

Purity: 97%

Color and Shape: White to dark cream to cream to orange to pale brown, Crystals or powder or crystalline powder or flakes

Molecular weight: 147.18

Ref: 02-L15762

Indole-3-carbinol

CAS: 700-06-1

Indole-3-carbinol

Formula: C₉H₉NO

Purity: ≥95%

Molecular weight: 147.17

Ref: 54-BUP18987

Indole-3-methanol

CAS: 700-06-1

Formula: C₉H₉NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 147.1739

Ref: IN-DA003R07

Indole-3-carbinol

CAS: 700-06-1

Formula: C₉H₉NO

Purity: ≥ 97.0%

Color and Shape: White to light-yellow or pale brown powder

Molecular weight: 147.18

Ref: 7W-GK5424

3-(Hydroxymethyl)-1H-indole

CAS: 700-06-1

3-(Hydroxymethyl)-1H-indole

Formula: C₉H₉NO

Purity: >98%

Color and Shape: White Solid

Molecular weight: 147.17386

Ref: 54-OR10179

Indole-3-carbinol

CAS: 700-06-1

Indole-3-carbinol (I3C), a naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, inhibits NF-κB and IκBα kinase

Formula: C₉H₉NO

Purity: 98.59% - >99.99%

Color and Shape: Solid

Molecular weight: 147.17

Ref: TM-T2947

Indole-3-carbinol

CAS: 700-06-1

Stability Unstable in solution
Applications Inhibits cancinogenesis at the initiation stage. A metabolite of 3-methylindole
References Stresser, D.M., et al.: J. Biochem. Toxicol., 10, 191 (1995), Bailey, G.S., et al.: J. Natl. Cancer Inst., 78, 931 (1987), D’Agostino et. al. Drug Metabolism and Disp. 27: 2018 (2009)

Formula: C₉H₉NO

Color and Shape: Neat

Molecular weight: 147.17

Ref: TR-I578000

Indole-3-carbinol

CAS: 700-06-1

Indole-3-carbinol is a fine chemical that has been used for research purposes as a reagent and speciality chemical. Indole-3-carbinol is also a versatile building block and reaction intermediate in organic synthesis, which has been used for the synthesis of many complex compounds. Indole-3-carbinol is also an important precursor to pharmaceuticals, including antiestrogens and anti-angiogenesis agents. Indole-3-carbinol has been shown to have antiinflammatory effects, which may be due to its ability to inhibit prostaglandin synthesis.

Formula: C₉H₉NO

Purity: Min. 99 Area-%

Molecular weight: 147.18 g/mol

Ref: 3D-I-2100

3-Indolemethanol

CAS: 700-06-1

3-Indolemethanol is a chemical compound that is used for chemiluminescent reaction. It can be used as an experimental model for studying the effects of 3-indolemethanol on murine hepatoma and human osteosarcoma cells in vitro. This compound has been shown to have oral hypoglycemic activity and to inhibit cancer cell growth. 3-Indolemethanol has also been shown to modulate signal pathways, such as the MAPK pathway, which may lead to pro-apoptotic protein activation or inhibition of physiological effects.

Formula: C₉H₉NO

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 147.18 g/mol

Ref: 3D-FI02853

Indole-3-carbinol

CAS: 700-06-1

Formula: C₉H₉NO

Purity: 97%

Color and Shape: Solid, White to off-white powder

Molecular weight: 147.177

Ref: 10-F045221

Indole-3-carbinol

CAS: 700-06-1

(1H-Indol-3-yl)methanol

Formula: C₉H₉NO

Purity: 98%

Molecular weight: 147.17

Ref: IN-DG11703