CAS 70261-82-4

4-[(4-Methylpiperazin-1-yl)methyl]aniline

Description:

4-[(4-Methylpiperazin-1-yl)methyl]aniline, with the CAS number 70261-82-4, is an organic compound characterized by its amine functional groups and piperazine moiety. This substance features a piperazine ring substituted with a methyl group, which enhances its basicity and solubility in polar solvents. The aniline component contributes to its potential as a building block in pharmaceuticals and agrochemicals, as it can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. The compound is typically a solid at room temperature and may exhibit moderate to high stability under standard conditions. Its properties, such as melting point, boiling point, and solubility, can vary based on purity and environmental factors. Additionally, due to the presence of both amine and aromatic groups, it may exhibit interesting biological activities, making it a candidate for further research in medicinal chemistry. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₁₂H₁₉N₃

InChI: InChI=1S/C12H19N3/c1-14-6-8-15(9-7-14)10-11-2-4-12(13)5-3-11/h2-5H,6-10,13H2,1H3

InChI key: InChIKey=NIXCVBFXLJWUTC-UHFFFAOYSA-N

SMILES: C(C1=CC=C(N)C=C1)N2CCN(C)CC2

Synonyms:

• 1-(4-Aminobenzyl)-4-Methylpiperazinediium
• 1-(4-Aminobenzyl)-4-methylpiperazine
• 1-Methyl-4-(4-Aminobenzyl)Piperazine
• 4-(4-Methylpiperazin-1-ylmethyl)phenylamine
• 4-[(4-Methyl-1-piperazinyl)methyl]benzenamine
• 4-[(4-Methyl-1-piperazinyl)methyl]benzeneamine
• 4-[(4-Methylpiperazin-1-yl)methyl]phenylamine
• Benzenamine, 4-[(4-methyl-1-piperazinyl)methyl]-
• 4-[(4-Methylpiperazin-1-yl)methyl]aniline
• 4-((4-methylpiperazin-1-yl)methyl)aniline

4-(4-Methylpiperazin-1-ylmethyl)phenylamine

CAS: 70261-82-4

Formula: C₁₂H₁₉N₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 205.2994

Ref: IN-DA005WLT

4-(4-Methyl-piperazin-1-ylmethyl)-phenylamine

CAS: 70261-82-4

4-(4-Methyl-piperazin-1-ylmethyl)-phenylamine

Purity: 98%

Molecular weight: 205.29936g/mol

Ref: 54-OR307771

4-(4-Methyl-piperazin-1-ylmethyl)-phenylamine

CAS: 70261-82-4

Formula: C₁₂H₁₉N₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 205.305

Ref: 10-F030753

4-(4-Methylpiperazin-1-ylmethyl)phenylamine

Controlled Product

CAS: 70261-82-4

Applications 4-(4-Methylpiperazin-1-ylmethyl)phenylamine is an intermediate used to prepare aminopyridopyrimidinones as tyrosine kinase inhibitors and anticancer agents. It is also used in the synthesis of piperazinyltrifluoromethylphenylquinolinylbenzonaphthyridinone derivatives with anticancer activities.
References Klutchko, S., et al.: J. Med. Chem., 41, 3276 (1998); Liu, Q., et al.: J. Med. Chem., 53, 7146 (2010)

Formula: C₁₂H₁₉N₃

Color and Shape: Neat

Molecular weight: 205.3

Ref: TR-M327310