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CAS 70374-39-9

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Lornoxicam

Description:
Lornoxicam is a non-steroidal anti-inflammatory drug (NSAID) belonging to the oxicam class, primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase enzymes (COX-1 and COX-2), which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. Lornoxicam exhibits a relatively rapid onset of action and is often utilized in the management of acute and chronic pain conditions, including osteoarthritis and postoperative pain. The compound is typically administered orally or via injection, and its pharmacokinetics indicate good absorption and distribution in the body. Lornoxicam is known for its favorable safety profile compared to traditional NSAIDs, although it may still pose risks such as gastrointestinal irritation and cardiovascular effects. Its chemical structure includes a pyridine ring and a thiazine moiety, contributing to its pharmacological activity. As with any medication, it is essential to use Lornoxicam under medical supervision to mitigate potential side effects and interactions with other drugs.
Formula:C13H10ClN3O4S2
InChI:InChI=1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChI key:InChIKey=WLHQHAUOOXYABV-UHFFFAOYSA-N
SMILES:OC=1C2=C(S(=O)(=O)N(C)C1C(NC3=CC=CC=N3)=O)C=C(Cl)S2
Synonyms:
  • (3E)-6-chloro-3-[hydroxy(pyridin-2-ylamino)methylidene]-2-methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]thiazin-4-one 1,1-dioxide
  • 2H-Thieno(2,3-E)-1,2-Thiazine-3-Carboxamide,6-Chloro-4-
  • 2H-Thieno[2,3-e]-1,2-thiazine-3-carboxamide, 6-chloro-4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide
  • 6-Chloro-4-Hydroxy-2-Methyl-N-2-Pyridinyl-2H-Thieno[2,3-
  • 6-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide-1,1-dioxide
  • Akos 93662
  • Chlortenoxicam
  • E]-1,2-Thiazine-3-Carboxamide 1,1-Dioxide
  • Fulactive
  • Hydroxy-2-Methyl-N-2-Py
  • See more synonyms
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