CAS 70648-26-9
:1,2,3,4,7,8-Hexachlorodibenzofuran
Description:
1,2,3,4,7,8-Hexachlorodibenzofuran (CAS 70648-26-9) is a chlorinated aromatic compound belonging to the dibenzofuran family. It is characterized by the presence of six chlorine atoms substituted on the dibenzofuran structure, which consists of two fused benzene rings connected by an oxygen atom. This compound is typically a white to off-white solid and is known for its persistence in the environment, as well as its potential for bioaccumulation in living organisms. 1,2,3,4,7,8-Hexachlorodibenzofuran is classified as a polychlorinated dibenzofuran (PCDF), which are known for their toxicological effects, including carcinogenicity and endocrine disruption. Its production and use are largely restricted due to environmental and health concerns. The compound is often monitored in environmental samples, particularly in relation to industrial processes and waste management, as it can be released as a byproduct of combustion and other chemical processes. Proper handling and disposal are crucial to mitigate its environmental impact.
Formula:C12H2Cl6O
InChI:InChI=1S/C12H2Cl6O/c13-4-1-3-6(2-5(4)14)19-12-7(3)8(15)9(16)10(17)11(12)18/h1-2H
InChI key:InChIKey=LVYBAQIVPKCOEE-UHFFFAOYSA-N
SMILES:ClC1=C2C=3C(OC2=C(Cl)C(Cl)=C1Cl)=CC(Cl)=C(Cl)C3
Synonyms:- 1,2,3,4,7,8-Hcdf
- 1,2,3,4,7,8-Hexachlorodibenzofuran
- 1,2,3,4,7,8-HxCDF
- F 118
- Pcdf 118
- Dibenzofuran, 1,2,3,4,7,8-hexachloro-
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Found 6 products.
1,2,3,4,7,8-Hexachlorodibenzofuran
CAS:1,2,3,4,7,8-Hexachlorodibenzofuran (1,2,3,4,7,8-HxCDF) enhances the expression of CYP1A1, CYP1B1, and aryl hydrocarbon receptor repressor (AhRR) genes in human peripheral blood lymphocytes (PBL). It can activate ethoxyresorufin-O-deethylase (EROD), with a BMR20TCDD within the range of 0.115-0.143 nM, corresponding to 20% of the maximum response induced by TCDD.Formula:C12H2Cl6OColor and Shape:SolidMolecular weight:374.861,2,3,4,7,8-Hexachlorodibenzofuran 50 µg/mL in Nonane
CAS:Formula:C12H2Cl6OColor and Shape:Single SolutionMolecular weight:374.861,2,3,4,7,8-Hexachlorodibenzofuran (>90%)
CAS:Applications 1,2,3,4,7,8-hexachlorodibenzofuran, is a toxic polychlorinated dibenzofurans (PCDD/F), detected in domestic meat and poultry. It can be used as purified standards for analytical, toxic, and biological studies of these environmental contaminants.
References Huwe, J., et al.: Food Addit. Contam., 21, 182 (2004), Llobet, J., et al.: Toxicol. Lett., 178, 117 (2008); Feil, V., et al.: J. Agric. Food Chem., 48, 6163 (2000); Safe, S. H., et al.: J. Agric. Food Chem., 32, 68 (1984);Formula:C12H2Cl6OPurity:>90%Color and Shape:NeatMolecular weight:374.86
