CAS 706782-28-7

Pimavanserin tartrate

Description:

Pimavanserin tartrate is a novel antipsychotic medication primarily used for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis. It functions as a selective inverse agonist of the 5-HT2A serotonin receptor, which distinguishes it from traditional antipsychotics that often target multiple neurotransmitter systems. This selectivity contributes to its unique profile, minimizing the risk of extrapyramidal side effects commonly associated with other antipsychotic drugs. Pimavanserin is typically administered in the form of its tartrate salt, enhancing its solubility and bioavailability. The compound is characterized by its relatively low affinity for dopamine receptors, which is a significant factor in its therapeutic application. Its pharmacokinetics indicate a moderate half-life, allowing for once-daily dosing. Additionally, pimavanserin has been studied for its potential effects on other neuropsychiatric conditions, although its primary indication remains within the realm of Parkinson's disease. Overall, pimavanserin tartrate represents a significant advancement in the management of psychosis in patients with Parkinson's disease, offering a targeted approach with a favorable side effect profile.

Formula: C₂₅H₃₄FN₃O₂C₄H₆O₆

InChI: InChI=1S/C25H34FN3O2.C4H6O6/c1-19(2)18-31-24-10-6-20(7-11-24)16-27-25(30)29(23-12-14-28(3)15-13-23)17-21-4-8-22(26)9-5-21;5-1(3(7)8)2(6)4(9)10/h4-11,19,23H,12-18H2,1-3H3,(H,27,30);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1

InChI key: InChIKey=XTTVNKCYECPJOF-LREBCSMRSA-N

SMILES: N(CC1=CC=C(F)C=C1)(C(NCC2=CC=C(OCC(C)C)C=C2)=O)C3CCN(C)CC3.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O

Synonyms:

• ACP 103
• Urea, N-[(4-fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N′-[[4-(2-methylpropoxy)phenyl]methyl]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
• Pimavanserin Tartrate
• Pimavanserin tartrate

Unii-na83F1sjsr

CAS: 706782-28-7

Formula: C₅₄H₇₄F₂N₆O₁₀

Purity: 99%

Color and Shape: Solid

Molecular weight: 1005.1964

Ref: IN-DA00FDRC

Pimavanserin Hemitartrate

CAS: 706779-91-1, 706782-28-7

Formula: C₂₅H₃₄FN₃O₂·5C₄H₆O₆

Color and Shape: White To Off-White Solid

Molecular weight: 427.56 0.5*150.09

Ref: 4Z-P-281002

Pimavanserin tartrate

CAS: 706782-28-7

Pimavanserin tartrate

Formula: C₅₀H₆₈F₂N₆O₄·C₄H₆O₆

Purity: ≥98%

Molecular weight: 1005.2

Ref: 54-BUP17169

Pimavanserin tartrate

CAS: 706782-28-7

Pimavanserin tartrate is a potent 5-HT 2A receptor inverse agonist used to treat Parkinson's disease-related psychosis.Cost-effective and quality-assured.

Formula: C₅₀H₆₈F₂N₆O₄·C₄H₆O₆

Purity: 99.24% - 99.98%

Color and Shape: White Solid

Molecular weight: 1005.2

Ref: TM-T6946

Pimavanserin tartrate

CAS: 706782-28-7

Serotonin receptor 5-HT2A inverse agonist

Formula: (C₂₅H₃₄FN₃O₂)₂•C₄H₆O₆

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 1,005.2 g/mol

Ref: 3D-FP104271

Pimavanserin tartrate - Bio-X ™

CAS: 706782-28-7

Pimavanserin is an atypical antipsychotic drug that is used for the treatment of symptoms associated with Parkinson’s disease. Although this drug’s mechanism of action is not fully understood, it is said to act via inverse agonist at serotonin 5-HT2A receptors to aid with the symptoms.

Formula: (C₂₅H₃₄FN₃O₂)₂•C₄H₆O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,005.2 g/mol

Ref: 3D-BP164269

Pimavanserin Tartrate

Controlled Product

CAS: 706782-28-7

Formula: C₂₅H₃₄FN₃O₂C₄H₆O₆

Color and Shape: Neat

Molecular weight: 502.595

Ref: TR-P441810

Pimavanserin Hemitartrate

CAS: 706782-28-7

Formula: C₂₅H₃₄FN₃O₂(C₄H₆O₆)

Molecular weight: 427.6 : 1/2(150.1)

Ref: ST-EA-CP-P112026